scholarly journals Biochemical and Anthropometric Effects of a Weight Loss Dietary Supplement in Healthy Men and Women

2011 ◽  
Vol 5 ◽  
pp. NMI.S8566 ◽  
Author(s):  
Cameron G. McCarthy ◽  
Robert E. Canale ◽  
Rick J. Alleman ◽  
Jacob P. Reed ◽  
Richard J. Bloomer
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Weight ◽  
Dietary Supplement ◽  
Primary Outcome ◽  
Skinfold Thickness ◽  
Resting Heart Rate ◽  
Post Intervention ◽  
Men And Women ◽  
Oxyelite Pro

Background We have recently noted an acute increase in circulating free fatty acids and glycerol, as well as resting metabolic rate, when men and women ingested the dietary supplement OxyELITE Pro™ in a single dose. We have also noted a reduction in appetite when subjects were treated with this supplement for 14 consecutive days. It is possible that such findings may favor body weight and fat loss over time. Therefore, the purpose of the present study was to determine the effects of this dietary supplement on weight loss and associated markers using an eight week intervention. Methods Exercise-trained subjects were randomly assigned in double blind manner to ingest either the dietary supplement (n = 16; aged 22.8 ± 0.7) or a placebo (n = 16; 22.5 ± 0.5) every day for eight weeks. Body weight, body composition, skinfold thickness, serum lipids, and appetite were measured as the primary outcome variables. As measures of supplement safety, a complete blood count and comprehensive metabolic panel were performed, and resting heart rate and blood pressure were measured (pre and post intervention). Results No interactions or main effects were noted for our primary outcome measures ( P > 0.05). However, when comparing pre and post intervention values for the supplement, significant decreases were noted in appetite, body weight, body fat percentage, and skinfold thickness ( P < 0.05), while increases were noted for total and HDL-C, as well as for resting heart rate ( P < 0.05). No changes were noted for placebo from pre to post intervention ( P > 0.05), with the exception of an increase in HDL-C ( P < 0.05). Blood pressure and bloodborne safety variables were not differently impacted by supplement or placebo ( P > 0.05), with the exception of monocytes, for which an interaction effect was noted ( P = 0.04). Conclusion These data indicate that the dietary supplement OxyELITE Pro™ may assist in weight and body fat loss in a sample of exercise-trained men and women. The supplement does not result in any adverse effects pertaining to resting blood pressure or bloodborne markers of safety; however a small increase in resting heart rate is observed.

scholarly journals A Dietary Supplement Containing Chlorophytum Borivilianum and Velvet Bean Improves Sleep Quality in Men and Women

2012 ◽  
Vol 7 ◽  
pp. IMI.S9720 ◽  
Author(s):  
Cameron G. McCarthy ◽  
Rick J. Alleman ◽  
Zach W. Bell ◽  
Richard J. Bloomer
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Sleep Quality ◽  
Dietary Supplement ◽  
Resting Heart Rate ◽  
Active Ingredients ◽  
Velvet Bean ◽  
Men And Women ◽  
Chlorophytum Borivilianum ◽  
Impaired Sleep

Background Impaired sleep quality is commonplace within industrialized societies, as evidenced by the increasing number of prescription sleep aids available. Certain herbal preparations have been suggested to provide a natural benefit to sleep; however, limited controlled data are available documenting this benefit. In the present study we tested the effect of an experimental dietary supplement, containing the active ingredients Chlorophytum borivilianum and Velvet bean, on sleep quality using the Pittsburgh Sleep Quality Index (PSQI). Methods Eighteen healthy and active men and women, with evidence of impaired sleep quality, consumed the supplement daily for 28 days. The PSQI was administered before and after the intervention period. As indicators of safety, resting heart rate and blood pressure were measured, and a complete blood count, comprehensive metabolic panel, and lipid panel were determined. Results Sleep quality was influenced by the supplement, as evidenced by an improvement in every category of the PSQI questionnaire ( P < 0.05), with most category scores improving approximately 50% from pre to post intervention. No adverse outcomes were noted with use of the supplement, as indicated by no change in resting heart rate, blood pressure, or any bloodborne parameter. Conclusions An investigational dietary supplement containing the active ingredients Chlorophytum borivilianum and Velvet bean improves sleep quality in men and women. Additional placebo controlled trials are needed to corroborate these findings in individuals with self-reported sleeping difficulty.

scholarly journals A Finished Dietary Supplement Stimulates Lipolysis and Metabolic Rate in Young Men and Women

2011 ◽  
Vol 5 ◽  
pp. NMI.S8567 ◽  
Author(s):  
Cameron G. McCarthy ◽  
Tyler M. Farney ◽  
Robert E. Canale ◽  
Rick J. Alleman ◽  
Richard J. Bloomer
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Metabolic Rate ◽  
Dietary Supplement ◽  
Body Fat ◽  
Rate Pressure Product ◽  
Healthy Human ◽  
Men And Women ◽  
Fat Loss ◽  
Oxyelite Pro

Background Dietary supplements are often marketed to increase lipolysis and thermogenesis, with the proposed end result being weight loss and body fat reduction. It was the purpose of the present investigation to study the acute effects of a weight/fat loss supplement within a sample of healthy human subjects. Methods Twelve subjects (men 24.8 ± 4.3 yrs; women 22.8 ± 0.4 yrs) ingested a dietary supplement (OxyELITE Pro™) or a placebo, on two separate days in a double-blind, cross-over design. Blood samples were collected immediately before ingestion, and at 60 and 120 minutes post ingestion, and analyzed for plasma glycerol and free fatty acids (FFA). Breath samples were collected immediately before ingestion and at 30, 60, 90, and 120 minutes post ingestion, for a measure of kilocalorie expenditure using indirect calorimetry. Area under the curve (AUC) was calculated. Heart rate and blood pressure were recorded at all times and rate pressure product (RPP) was calculated. Results AUC was greater for supplement compared to placebo for glycerol (22.74 ± 1.98 μg · mL-1 · 2 hr-1 vs. 15.76 ± 1.36 μg · mL-1 · 2 hr-1; P = 0.001), FFA(1.62 ± 0.07 mmol · L-1 · 2 hr-1 vs. 0.78 ± 0.12 mmol · L-1 · 2 hr-1; P < 0.0001), and kilocalorie expenditure (149 ± 7 kcal · 2 hr-1 vs. 122 ± 8 kcal · 2 hr-1; P = 0.005). Heart rate ( P = 0.02), systolic blood pressure ( P < 0.0001), and RPP ( P = 0.002) were higher for supplement compared to placebo. Conclusion Ingestion of OxyELITE Pro™ resulted in an increase in blood markers of lipolysis, as well as metabolic rate, during a two-hour post ingestion time period. An increase in hemodynamic variables was also observed. These findings are in reference to a sample of healthy men and women who were naïve to treatment with the dietary supplement. Additional work is needed to determine if the acute changes observed here would persist with chronic use of the supplement and possibly lead to weight/body fat loss over time.

scholarly journals Impact of Nuun Electrolyte Tablets on Fluid Balance in Active Men and Women

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3030
Author(s):  
Jacquelyn Pence ◽  
Richard J. Bloomer
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Weight ◽  
Single Dose ◽  
Fluid Balance ◽  
Effective Means ◽  
Body Weight Loss ◽  
Men And Women ◽  
Adequate Hydration ◽  
The Impact

Background: Maintaining adequate hydration is important for overall health and has major implications for athletes involved in physically demanding tasks. While water is viewed as an effective means to rehydrate, and is inexpensive and readily available, electrolyte beverages appear to be more beneficial, in particular for athletes who routinely lose electrolytes through sweating. Nuun tablets contain a mix of electrolytes and are quickly dissolved in water to create an electrolyte-rich beverage. We determined the impact of Nuun tablets on the fluid balance of healthy, exercise-trained men and women at rest. Methods: Eight men (25.9 ± 4.5 yrs) and 10 women (28.2 ± 9.4 yrs) ingested either water only or water with Nuun electrolyte tablets, at both a single and double strength concentration, in random order, on three occasions separated by approximately one week, in a fasted and euhydrated state. A total of 1 L of fluid was ingested at each visit over a 30 min period. Urine was collected from each subject at 0, 1, 2, 3, and 4 h post-ingestion. Urine mass values were used to calculate fluid balance and the beverage hydration index (BHI; i.e., the volume of urine produced after drinking the Nuun beverages, relative to that of water only—control condition). Heart rate and blood pressure were measured throughout the four-hour period, while body weight was measured at the start and end of the experiment. Results: Neither heart rate nor blood pressure were impacted by beverage consumption. Nuun tablets resulted in a lower urine output compared to water, with fluid balances for both concentrations more favorable compared to water (p < 0.05), beginning at 2 h post-ingestion and continuing at the 3 h and 4 h times. Body weight loss was less with Nuun at the single dose (0.38 kg; p = 0.02) and double dose (0.43 kg; p = 0.08), compared to water (0.57 kg). The BHI was higher for Nuun (single dose in particular) compared to water at both 2 h (p = 0.05) and 4 h (p = 0.02). Conclusion: The addition of Nuun electrolyte tablets to water improves the fluid balance and BHI in healthy men and women. Results were similar for both concentrations, suggesting that additional electrolytes are not necessary when in a rested state. Future studies should determine the impact of various concentrations of the Nuun beverage during physical exercise—in particular, exercise in the heat, when sweat loss may be highest.

scholarly journals Impact of a Dietary Supplement Containing 1,3-Dimethylamylamine on Blood Pressure and Bloodborne Markers of Health: A 10-Week Intervention Study

2012 ◽  
Vol 5 ◽  
pp. NMI.S8885 ◽  
Author(s):  
Paul N. Whitehead ◽  
Brian K. Schilling ◽  
Tyler M. Farney ◽  
Richard J. Bloomer
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Dietary Supplement ◽  
Complete Blood Count ◽  
Density Lipoprotein ◽  
Post Intervention ◽  
Supplement Use ◽  
Lipid Panel ◽  
Resting Blood Pressure

Background 1,3-dimethylamylamine is a commonly used ingredient within dietary supplements. Our prior work with this agent indicates a transient increase in blood pressure (systolic in particular) following oral ingestion of a single dosage, but no significant increase in resting blood pressure following chronic ingestion. Moreover, intervention studies involving both two and eight weeks of treatment with finished products containing 1,3-dimethylamylamine indicate minimal or no change in bloodborne markers of health. The present study sought to extend these findings by using a 10 -week intervention trial to determine the change in selected markers of health in a sample of men. Methods 25 healthy men were randomly assigned to either a placebo (n = 13) or to a supplement containing 1,3-dimethylamylamine (n = 12) for a period of 10 weeks. Before and after the intervention, resting blood pressure and heart rate were measured, and blood samples were collected for determination of complete blood count, metabolic panel, and lipid panel. Results No significant differences were noted between conditions for blood pressure ( P > 0.05), although systolic blood pressure increased approximately 6 mmHg with the supplement (diastolic blood pressure decreased approximately 4 mmHg). A main effect for time was noted for heart rate ( P = 0.016), with values decreasing from pre to post intervention. There were significant main effects for time for creatinine (increased from pre to post intervention; P = 0.043) and alkaline phosphatase (decreased from pre to post intervention; P = 0.009), with no condition differences noted ( P > 0.05). There was a significant interaction noted for low density lipoprotein cholesterol (LDL-C) ( P = 0.043), with values decreasing in the supplement group from pre to post intervention approximately 7 mg · dL-1 ( P = 0.034). No other effects of significance were noted for bloodborne variables. Conclusion These data indicate that a dietary supplement containing 1,3-dimethylamylamine does not result in a statistically significant increase in resting heart rate or blood pressure (although systolic blood pressure is increased ~6 mmHg with supplement use). The supplement does not negatively impact bloodborne markers of health. Further study is needed involving a longer intervention period, a larger sample size, and additional measures of health and safety.

Relationship among anthropometric and hemodynamic variables in public servants of Sergipe

2020 ◽  
Vol 19 (2) ◽  
pp. 134
Author(s):  
Patrícia Morgana Ferreira Santos ◽  
Lúcio Marques Vieira Souza ◽  
Jymmys Lopes Dos Santos ◽  
Matheus Amarante Do Nascimento ◽  
Clésio Andrade Lima ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Weight ◽  
Cross Sectional Study ◽  
Physical Activities ◽  
Resting Heart Rate ◽  
Public Servants ◽  
Cross Sectional ◽  
Administrative Functions ◽  
Hemodynamic Variables

Physical activities have an important prophylactic effect against cardiovascular diseases, as they promote reduction in body weight and blood pressure levels, for example. Individuals working on administrative functions tend to be sedentary, with consequent risk of obesity. However, the relationship among anthropometric and hemodynamic variables is still inconsistent. Thus, the aim of this study was to analyze the correlation among anthropometric and hemodynamic parameters of public servants. This is an observational and cross-sectional study with a sample of 147 individuals. It was verified that normotensive men had higher body mass index than hypertensive men. In contrast, these individuals showed higher resting heart rate values. It was noted that none of the anthropometric variables were associated with systolic and diastolic blood pressure; the associations verified were among anthropometric variables (r = 0.738 - body weight and hip; and r = 0.936 - abdomen and waist circumference). Also, no associations among anthropometric variables, blood pressure indices and resting heart rate were observed. In conclusion, although anthropometric variables are good predictors of body adiposity, they are not necessarily related to hemodynamic variables. The practice of physical activities should be encouraged within work routines, at appropriate times, aiming to improve healthy habits and anthropometric indicators.Keywords: anthropometry, hemodynamics, public servants, cardiovascular risk, adiposity. 

Sex Differences in Cardiovascular Reactivity

2009 ◽  
Vol 23 (2) ◽  
pp. 77-84 ◽  
Author(s):  
Matthew C. Whited ◽  
Kevin T. Larkin
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Sex Differences ◽  
Gender Roles ◽  
Cardiovascular Reactivity ◽  
Task Type ◽  
Conflict Task ◽  
Men And Women ◽  
Conflicting Evidence ◽  
Blood Pressure Responses

Sex differences in cardiovascular reactivity to stress are well documented, with some studies showing women having greater heart rate responses than men, and men having greater blood pressure responses than women, while other studies show conflicting evidence. Few studies have attended to the gender relevance of tasks employed in these studies. This study investigated cardiovascular reactivity to two interpersonal stressors consistent with different gender roles to determine whether response differences exist between men and women. A total of 26 men and 31 women were assigned to either a traditional male-oriented task that involved interpersonal conflict (Conflict Task) or a traditional female-oriented task that involved comforting another person (Comfort Task). Results demonstrated that women exhibited greater heart rate reactions than men independent of the task type, and that men did not display a higher reactivity than women on any measure. These findings indicate that sex of participant was more important than gender relevance of the task in eliciting sex differences in cardiovascular responding.

scholarly journals Blood pressure and resting heart rate in 3-17-year-olds in Germany in 2003–2006 and 2014–2017

2021 ◽  
Author(s):  
Giselle Sarganas ◽  
Anja Schienkiewitz ◽  
Jonas D. Finger ◽  
Hannelore K. Neuhauser
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Children And Adolescents ◽  
Selection Rule ◽  
Age Groups ◽  
Resting Heart Rate ◽  
Cross Sectional ◽  
National Examination ◽  
School Aged Children ◽  
Analysis Measurement

AbstractTo track blood pressure (BP) and resting heart rate (RHR) in children and adolescents is important due to its associations with cardiovascular outcomes in the adulthood. Therefore, the aim of this study was to examine BP and RHR over a decade among children and adolescents living in Germany using national examination data. Cross-sectional data from 3- to 17-year-old national survey participants (KiGGS 2003–06, n = 14,701; KiGGS 2014–17, n = 3509) including standardized oscillometric BP and RHR were used for age- and sex-standardized analysis. Measurement protocols were identical with the exception of the cuff selection rule, which was accounted for in the analyses. Different BP and RHR trends were observed according to age-groups. In 3- to 6-year-olds adjusted mean SBP and DBP were significantly higher in 2014–2017 compared to 2003–2006 (+2.4 and +1.9 mm Hg, respectively), while RHR was statistically significantly lower by −3.8 bpm. No significant changes in BP or in RHR were observed in 7- to 10-year-olds over time. In 11- to 13-year-olds as well as in 14- to 17-year-olds lower BP has been observed (SBP −2.4 and −3.2 mm Hg, respectively, and DBP −1.8 and −1.7 mm Hg), while RHR was significantly higher (+2.7 and +3.7 bpm). BP trends did not parallel RHR trends. The downward BP trend in adolescents seemed to follow decreasing adult BP trends in middle and high-income countries. The increase in BP in younger children needs confirmation from other studies as well as further investigation. In school-aged children and adolescents, the increased RHR trend may indicate decreased physical fitness.

scholarly journals Heart rate variability and blood pressure among Japanese men and women: a community-based cross-sectional study

2014 ◽  
Vol 37 (8) ◽  
pp. 779-784 ◽  
Author(s):  
Hiromi Mori ◽  
Isao Saito ◽  
Eri Eguchi ◽  
Koutatsu Maruyama ◽  
Tadahiro Kato ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Japanese Men ◽  
Men And Women
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