scholarly journals Effects of High Fat Feeding on Adipose Tissue Gene Expression in Diabetic Goto-Kakizaki Rats

2015 ◽  
Vol 9 ◽  
pp. GRSB.S25172 ◽  
Author(s):  
Bai Xue ◽  
Jing Nie ◽  
Xi Wang ◽  
Debra C. DuBois ◽  
William J. Jusko ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
High Fat ◽  
Adipose Tissue Gene Expression ◽  
Fat Feeding ◽  
Tissue Gene Expression

scholarly journals Eicosapentaenoic acid regulates brown adipose tissue gene expression and metabolism in high fat fed mice (1037.5)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Mandanna Pahlavani ◽  
Nishan Kalupahana ◽  
Monique LeMieux ◽  
Arwa Aljawadi ◽  
Shane Scoggin ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Eicosapentaenoic Acid ◽  
Brown Adipose Tissue ◽  
High Fat ◽  
Brown Adipose ◽  
Adipose Tissue Gene Expression ◽  
Tissue Gene Expression

TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation

2012 ◽  
Vol 123 (9) ◽  
pp. 547-555 ◽  
Author(s):  
Stella Bernardi ◽  
Giorgio Zauli ◽  
Christos Tikellis ◽  
Riccardo Candido ◽  
Bruno Fabris ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Inflammatory Cytokines ◽  
Systemic Inflammation ◽  
Tolerance Test ◽  
Metabolic Abnormalities ◽  
High Fat ◽  
Adipose Tissue Gene Expression ◽  
Tissue Gene Expression ◽  
Pro Inflammatory Cytokines

TRAIL [TNF (tumour necrosis factor)-related apoptosis-inducing ligand] has recently been shown to ameliorate the natural history of DM (diabetes mellitus). It has not been determined yet whether systemic TRAIL delivery would prevent the metabolic abnormalities due to an HFD [HF (high-fat) diet]. For this purpose, 27 male C57bl6 mice aged 8 weeks were randomly fed on a standard diet, HFD or HFD+TRAIL for 12 weeks. TRAIL was delivered weekly by intraperitoneal injection. Body composition was evaluated; indirect calorimetry studies, GTT (glucose tolerance test) and ITT (insulin tolerance test) were performed. Pro-inflammatory cytokines, together with adipose tissue gene expression and apoptosis, were measured. TRAIL treatment reduced significantly the increased adiposity associated with an HFD. Moreover, it reduced significantly hyperglycaemia and hyperinsulinaemia during a GTT and it improved significantly the peripheral response to insulin. TRAIL reversed the changes in substrate utilization induced by the HFD and ameliorated skeletal muscle non-esterified fatty acids oxidation rate. This was associated with a significant reduction of pro-inflammatory cytokines together with a modulation of adipose tissue gene expression and apoptosis. These findings shed light on the possible anti-adipogenic and anti-inflammatory effects of TRAIL and open new therapeutic possibilities against obesity, systemic inflammation and T2DM (Type 2 DM).

scholarly journals Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets

Diabetologia ◽  
2004 ◽  
Vol 48 (1) ◽  
pp. 123-131 ◽  
Author(s):  
N. Viguerie ◽  
H. Vidal ◽  
P. Arner ◽  
C. Holst ◽  
C. Verdich ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
High Fat ◽  
Low Fat ◽  
Obese Subjects ◽  
Adipose Tissue Gene Expression ◽  
Tissue Gene Expression

scholarly journals Differences in Muscle and Adipose Tissue Gene Expression and Cardio-Metabolic Risk Factors in the Members of Physical Activity Discordant Twin Pairs

PLoS ONE ◽  
2010 ◽  
Vol 5 (9) ◽  
pp. e12609 ◽  
Author(s):  
Tuija Leskinen ◽  
Rita Rinnankoski-Tuikka ◽  
Mirva Rintala ◽  
Tuulikki Seppänen-Laakso ◽  
Eija Pöllänen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Physical Activity ◽  
Risk Factors ◽  
Adipose Tissue ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Adipose Tissue Gene Expression ◽  
Tissue Gene Expression ◽  
Discordant Twin

Central injection of oxytocin reduces food intake and affects hypothalamic and adipose tissue gene expression in chickens

2019 ◽  
Vol 67 ◽  
pp. 11-20
Author(s):  
Betty R. McConn ◽  
Anna Koskinen ◽  
D. Michael Denbow ◽  
Elizabeth R. Gilbert ◽  
Paul B. Siegel ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Food Intake ◽  
Adipose Tissue Gene Expression ◽  
Tissue Gene Expression
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