scholarly journals Commonality between Diabetes and Alzheimer's Disease and a New Strategy for the Therapy

2008 ◽  
Vol 1 ◽  
pp. CPath.S667 ◽  
Author(s):  
Li Lin
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
New Strategy

Time for a New Strategy in the War on Alzheimer’s Disease

2019 ◽  
Vol 29 (4) ◽  
pp. 119-122
Author(s):  
Matt Kaeberlein
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Molecular Mechanisms ◽  
Well Being ◽  
Developed Countries ◽  
Biological Aging ◽  
Root Cause ◽  
New Strategy ◽  
New Strategies ◽  
Made In

Abstract Alzheimer’s disease is a growing threat to the economic and social well-being of developed countries around the globe, but efforts to delay, prevent, or cure this disorder have yet to yield success. I believe the lack of progress largely results from approaches that ignore the most important component of Alzheimer’s disease: biological aging. Major advances have been made in understanding the molecular mechanisms that link biological aging to disease. These mechanisms have been formalized as nine hallmarks, or pillars, of aging. Here, I discuss the barriers that have impaired progress and propose specific steps that can be taken to overcome these barriers. The time has come to adopt bold new strategies that tackle biological aging as the root cause of Alzheimer’s disease.

scholarly journals Exploring the Multi–Target Neuroprotective Chemical Space of Benzofuran Scaffolds: A New Strategy in Drug Development for Alzheimer’s Disease

2020 ◽  
Vol 10 ◽  
Author(s):  
Jaime R. Cabrera-Pardo ◽  
Jorge Fuentealba ◽  
Javiera Gavilán ◽  
Daniel Cajas ◽  
José Becerra ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Drug Development ◽  
Chemical Space ◽  
New Strategy

A proposed new strategy of immunotherapy for Alzheimer's disease

1997 ◽  
Vol 49 (4) ◽  
pp. 319-326 ◽  
Author(s):  
K. Ga̧siorowski ◽  
J. Leszek
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
New Strategy

Novel selective butyrylcholinesterase inhibitors as a new strategy for the treatment of Alzheimer's disease

2000 ◽  
Vol 21 ◽  
pp. 274
Author(s):  
Nigel H. Greig ◽  
Qian-sheng Yu ◽  
Tada Utsuki ◽  
Harold W. Halloway ◽  
Donald K. Ingram ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
New Strategy

scholarly journals Treatment for alzheimer's disease: The present and future

2021 ◽  
Vol 271 ◽  
pp. 03018
Author(s):  
Cheng Wei
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Early Stage ◽  
Health Crisis ◽  
Mutant Proteins ◽  
Stage Of Development ◽  
High Penetration ◽  
New Strategy ◽  
Delivery Platform ◽  
Shock Proteins

Alzheimer's disease (AD) is a growing global health crisis, however, there are currently very few effective treatments for it. All existent treatments serve only to ameliorate the symptoms of AD instead of curing it. With the deepening of the disease pathology in recent years, there have been many studies and clinical trials that aim to discover new disease-modifying therapies. Nanoparticle drug delivery platform is a promising path for its high penetration rate across the blood brain barrier, while heat shock proteins provide a new strategy to target the mutant proteins that cause AD. These novel therapies may help us better treat and potentially cure AD, but many of them are still in their early stage of development and their side effects are still unknown. A truly effective treatment for AD is still years ahead.

Sign in / Sign up

Export Citation Format

Share Document