scholarly journals Case Report of Ectopic Ovarian Pregnancy following Fresh Embryo Transfer

2016 ◽  
Vol 10 ◽  
pp. CMRH.S40593
Author(s):  
Nivin Samara ◽  
Yaakov Bentov
Keyword(s):  
Risk Factors ◽  
Embryo Transfer ◽  
Prevention Strategies ◽  
Fresh Embryo Transfer ◽  
Vitro Fertilization ◽  
Extrauterine Pregnancy ◽  
Ovarian Pregnancy ◽  
Clinical Phenomenon

Background Ovarian pregnancy is a rare and challenging clinical phenomenon. Recent studies have identified assisted reproductive treatments and infertility as risk factors. However, neither a definite mechanism nor clear risk factors were identified and therefore prevention strategies are yet unavailable. Clinical Case In this article, we present a case of ovarian pregnancy occurring following in vitro fertilization treatment and a fresh embryo transfer. The couple was diagnosed with unexplained infertility and no identifiable risk factors for extrauterine pregnancy. The diagnosis of ovarian pregnancy was made during explorative laparoscopy performed due to suspected extrauterine pregnancy. The patient had normal intra- and postoperative course. Conclusion Ovarian pregnancy is an infrequent and a challenging diagnosis. Yet, late diagnosis and lack of appropriate intervention may have long-term implications. Several mechanisms and risk factors are proposed, and their acknowledgment may improve early diagnosis and prevention of complications.

scholarly journals Ectopic ovarian pregnancy following in vitro fertilization: case report

2020 ◽  
Vol 9 (5) ◽  
pp. 2174
Author(s):  
Shrinkhla Khandelwal ◽  
Neeta Natu
Keyword(s):  
Risk Factors ◽  
In Vitro Fertilization ◽  
Ectopic Pregnancy ◽  
Transvaginal Sonography ◽  
Fresh Embryo Transfer ◽  
Pregnancy Risk ◽  
Vitro Fertilization ◽  
Ovarian Pregnancy ◽  
Clinical Phenomenon

Ovarian pregnancy is a rare form of extrauterine ectopic pregnancy. Risk factors such as reproductive treatments and infertility have been identified in recent studies. In this article, we present a case of ovarian ectopic pregnancy occurring following in vitro fertilization treatment and a fresh embryo transfer. The diagnosis of ovarian pregnancy was made during transvaginal sonography performed due to suspected ectopic pregnancy. Ovarian ectopic pregnancy is a rare clinical phenomenon. Late diagnosis and lack of appropriate intervention may have catastrophic results. Several mechanisms and risk factors are proposed, and their acknowledgment may improve early diagnosis and prevention of complications.

scholarly journals Epigenetic Effects of Assisted Reproductive Technology in Human Offspring

2019 ◽  
Author(s):  
Wei Chen ◽  
Yong Peng ◽  
Xinyi Ma ◽  
Siming Kong ◽  
Shuangyan Tang ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Assisted Reproductive Technologies ◽  
Adult Life ◽  
Reproductive Technologies ◽  
Fresh Embryo Transfer ◽  
Vitro Fertilization ◽  
Nuclear Families ◽  
Genome Wide ◽  
Parental Background

AbstractThe births of more than 8 million infants have been enabled globally through assisted reproductive technologies (ARTs), including conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with either fresh embryo transfer (ET) or frozen embryo transfer (FET). However, the potential for elevated risks of ART-related disorders persists in adult life, and the underlying epigenetic mechanisms are largely uncharacterized. Here, we recruited 100 nuclear families and profiled the DNA methylomes, genome-wide histone modifications and transcriptomes to clarify the inherent extra risks attributable to specific ART procedures. We discovered that IVF-ET seemed to introduce less disturbance into the infant epigenome than IVF-FET or ICSI-ET did. Furthermore, we noted approximately half of the DNA methylomic changes in ART-conceived offspring could be explained by parental background biases. Through removal of the parental effect, we confirmed that ART per se would introduce minor DNA methylation changes locally. More importantly, we found that ART-induced epigenomic alterations were highly enriched in the processes which might contribute to increased incidence of preeclampsia during pregnancy and metabolic syndrome in offspring. Overall, our study provides an epigenetic basis for the potential long-term health risks in ART-conceived offspring that reinforces the need to review all methods of human ART.

scholarly journals Use of a new set of key performance indicators for evaluating the performance of an in vitro fertilization laboratory in which blastocyst culture and the freeze-all strategy are the primary treatment in patients with in vitro fertilization

2021 ◽  
Vol 49 (9) ◽  
pp. 030006052110443
Author(s):  
Hui-tian Wang ◽  
Ping-ping Hong ◽  
Hai-yang Li ◽  
Wen Zhou ◽  
Tao Li
Keyword(s):  
In Vitro Fertilization ◽  
Embryo Transfer ◽  
Performance Indicators ◽  
Implantation Rate ◽  
Key Performance Indicators ◽  
Control Analysis ◽  
Fresh Embryo Transfer ◽  
Blastocyst Culture ◽  
Vitro Fertilization

Objective To evaluate the performance of an in vitro fertilization (IVF) laboratory using a new set of key performance indicators (KPIs) when the main treatment of IVF patients had been changed. Methods Patients who underwent fresh embryo transfer and the freeze-all strategy in August, September, and October 2017 were retrospectively studied to evaluate the performance of an IVF laboratory in September when implantation rate of fresh embryo transfer decreased. KPIs associated with blastocyst culture and the first frozen embryo transfer (FET) cycle in patients with the freeze-all strategy were compared over 3 months. Results Day 5 usable blastocyst and good quality blastocyst rates, and day 3 usable/good quality embryo rates were not different among the three periods. The implantation rate and KPIs associated with morphological changes in warmed blastocysts in the first FET cycle in patients with the freeze-all strategy were also not different among the periods. Conclusions KPIs associated with embryo quality, blastocyst culture, and the pregnancy outcome of the first FET cycle in patients with the freeze-all strategy suggested that performance was unaffected in our IVF laboratory in September. These KPIs might be useful for internal quality control analysis of IVF laboratories.

scholarly journals Retrospective study of multiple factors imparting effect on pregnancy outcomes in an in-vitro-fertilization centre

2020 ◽  
Vol 9 (6) ◽  
pp. 2516
Author(s):  
Preksha T. Singh ◽  
Shreyans D. Singhvi ◽  
Utkarsh Kachhia ◽  
Trishala Punjabi ◽  
Shital Punjabi ◽  
...  
Keyword(s):  
Retrospective Study ◽  
In Vitro Fertilization ◽  
Embryo Transfer ◽  
Pregnancy Outcomes ◽  
Statistical Difference ◽  
P Value ◽  
Fresh Embryo Transfer ◽  
Vitro Fertilization ◽  
Multiple Factors

Background: Assisted reproductive technology (ART) cycles include in vitro fertilization of the sperm and ovum and transferring the embryo formed into the uterus of the patients. In ART cycles, there is still a shroud of doubt regarding the pregnancy outcomes of embryo transfer on day 3 versus the embryo transfers on day 5 as well the better pregnancy outcome with fresh versus frozen embryo transfer and the number of embryos transferred. This study is aimed to evaluate these factors and study the way to optimize methods to obtain highest pregnancy outcomes.Methods: A retrospective study was performed of 87 patients who had undergone embryo transfers during the duration of the study from an IVF centre in Ahmedabad. Multiple factors were studied and the clinical outcome was tabulated. The pregnancy outcomes were compared using the values of beta- hcg (human chorionic gonadotropin). The data was compiled and analyzed using Google spreadsheets. To find the statistical difference between different factors- the statistical method of Fischer’s exact test and p-value was used.Results: No statistical difference between day 3 and day 5 embryo transfer as well as between frozen and fresh embryo transfer were both. All of them were found equally efficacious, although 3 and 5 number of embryo transfers were found efficacious.Conclusions: In conclusion authors recommend a day 5 embryo transfer with 3 or 5 embryos which are best-quality frozen or fresh embryos to achieve maximum pregnancy outcomes.

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