scholarly journals Article Commentary: A commentary on “Risk Factors for Renal Cell Cancer in a Japanese Population

2009 ◽  
Vol 3 ◽  
pp. CMO.S2926
Author(s):  
Esther Uña Cidon

The well-written and researched article reported in Clinical Medicine: Oncology by Dr. Washio and Dr. Mori entitled “Risk factors for renal cell cancer in a Japanese population” 1 makes evident the differences in incidence and mortality rates from renal cell carcinoma (RCC) between different populations and highlights the relevance of carrying out epidemiological studies, investigating additional risk factors which may explain the differences.

2002 ◽  
Vol 44 (11) ◽  
pp. 1028-1036 ◽  
Author(s):  
Stefano Mattioli ◽  
Davide Truffelli ◽  
Alberto Baldasseroni ◽  
Alessandro Risi ◽  
Bruno Marchesini ◽  
...  

2012 ◽  
Vol 30 (5_suppl) ◽  
pp. 371-371
Author(s):  
Eunyoung Cho ◽  
Hee-Kyung Joh ◽  
Toni K. Choueiri

371 Background: The genetic determinants of sporadic renal cell cancer (RCC) are largely unknown. Previous studies have suggested associations between the ABO blood group and risk of various cancers, however, its relationship to RCC remains unclear. Methods: We prospectively evaluated the association between the ABO blood group and risk of RCC in two large independent cohorts of women (the Nurses’ Health Study) and men (the Health Professionals Follow-up Study) from 1996 to 2008. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using Cox proportional hazards models with adjustment for other risk factors for RCC including obesity, smoking, and hypertension. All statistical tests were two-sided. Results: During 12 years of follow-up of 77 242 women and 29 548 men, 163 cases of incident RCC were documented in women and 84 cases in men. After multivariate adjustment, non-O blood group (combined group of A, AB, and B) was associated with a 1.5-fold elevated risk of RCC (95% CI 1.09–2.09) than O blood group in women. In contrast, no significant associations were observed between the ABO blood group and risk of RCC in men. The associations between the ABO blood group and RCC were consistent across strata of known risk factors including obesity, smoking status, and history of hypertension (Pinteraction≥ 0.58) in both cohorts. Conclusions: We show for the first time that non-O blood group is significantly associated with a higher risk of RCC compared with blood group O in women. Further studies that elucidate the biological mechanisms underlying this association are warranted.


1997 ◽  
Vol 145 (7) ◽  
pp. 607-613 ◽  
Author(s):  
C. W. Heath ◽  
C. A. Lally ◽  
E. E. Calle ◽  
J. K. McLaughlin ◽  
M. J Thun

2010 ◽  
Vol 34 (3) ◽  
pp. 226-231 ◽  
Author(s):  
Jalal Tarabeia ◽  
Dorit Nitzan Kaluski ◽  
Micha Barchana ◽  
Rita Dichtiar ◽  
Manfred S. Green

2004 ◽  
Vol 10 (6) ◽  
pp. 2015-2019 ◽  
Author(s):  
Masahiro Sasaki ◽  
Yuichiro Tanaka ◽  
Steven T. Okino ◽  
Mitsuharu Nomoto ◽  
Suguru Yonezawa ◽  
...  

2009 ◽  
Vol 3 ◽  
pp. CMO.S2669 ◽  
Author(s):  
Masakazu Washio ◽  
Mitsuru Mori

The incidence of renal cell cancer has been increasing worldwide. Although the incidence of renal cell cancer in Japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing. In this paper, we would like to introduce the result of our studies, which evaluate the risk factors for renal cell cancer in Japan. Hypertension, diabetes mellitus, kidney diseases, fondness for fatty food and black tea showed an increased risk of renal cell carcinoma while an intake of starchy roots such as taro, sweet potato and potato reduced the risk of renal cell carcinoma. In Japan, however, drinking black tea may be a surrogate for westernized dietary habits while eating starchy roots may be a surrogate for traditional Japanese dietary habits. Further studies may be needed to evaluate risk factors for renal cell cancer because the number of renal cancer cases was small in our studies in spite of a large population-based cohort study.


2016 ◽  
Vol 15 (5) ◽  
pp. e1189
Author(s):  
M. Markevičius ◽  
M. Kinčius ◽  
M. Jakubovskis ◽  
V. Lietuvietis ◽  
J. Auziņš ◽  
...  

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