scholarly journals A Challenging Picture of Cancer-and Inflammation-Related Changes

2009 ◽  
Vol 3 ◽  
pp. CMO.S2104 ◽  
Author(s):  
Carsten Nieder ◽  
Rolf E. Steen ◽  
Astrid Dalhaug

The authors describe a diagnostically challenging case where a patient with previous squamous cell carcinoma of the tonsil developed a putative second primary squamous cell carcinoma in the lung (stage IV with lung and bone metastases). During palliative chemotherapy several episodes of severe infection occurred, eventually resulting in abscess formation in the hip and brain. The dilemma of distinguishing between metastasis and abscess and the therapeutic implications are discussed.

1989 ◽  
Vol 75 (5) ◽  
pp. 489-493 ◽  
Author(s):  
Massimo Gion ◽  
Carlo Tremolada ◽  
Riccardo Mione ◽  
Paolo della Palma ◽  
Ruggero Dittadi ◽  
...  

Serum levels of several tumor markers were studied in 96 patients with untreated primary squamous cell carcinoma of the esophagus. Three markers specific for digestive tract malignancies - CEA, CA19.9 and CA50 - and two non organ specific indicators of malignancy - ferritin and TPA - were evaluated. Positivity rates of CAI9.9 and CA50 were very low (4.4 % and 8.6 % respectively); the markers were therefore considered ineffective in the disease. CEA, TPA and ferritin showed a fair positivity rate (27.1 %, 28.1 %, 33.7% respectively); CEA and TPA were directly related to clinical stage, CEA levels being significantly higher in stage IV than in stage III cases (p = 0.016). TPA preoperatory levels were also directly related to a lower survival probability (p = 0.004). CEA showed significantly lower levels in tumors of lower than in those of middle (p = 0.03) and upper esophagus (p = 0.004). TPA showed a similar behaviour with lower levels in tumors of lower than of middle esophagus (p = 0.03). These findings could be due to a bulky metabolism of tumor markers drained via portail vein in the liver. From our data the following conclusions may be drawn: 1) CEA and TPA may be useful in the staging of esophageal cancer as an ancillary tool to assess the extent of the disease; 2) tumor location is an important variable when evaluating blood levels of tumor markers in patients with esophageal cancer.


1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Lingquan Kong

Objective: To investigate the clinicopathological features and prognosis of primary squamous cell carcinoma of the breast. Methods: 2 cases of primary squamous cell carcinoma of the breast were analyzed. According to the TNM stage of breast cancer, the patients underwent hematectomy and stage IV and stage II. All the patients were treated with radiotherapy. Results: The age of onset was younger, ER / PR was negative, and 4 months after operation, no recurrence or distant metastasis was found. Conclusion: The clinical features of primary squamous cell carcinoma lack specificity, misdiagnosis, need to pay attention to differential diagnosis, standardized diagnosis and treatment strategy still need further study.


2019 ◽  
Vol 5 (3) ◽  
pp. 100103
Author(s):  
Masahiko Terauchi ◽  
Mari Shibata ◽  
Akane Wada ◽  
Yasuyuki Michi ◽  
Satoshi Yamaguchi ◽  
...  

ORL ◽  
1998 ◽  
Vol 60 (3) ◽  
pp. 170-173 ◽  
Author(s):  
Masayuki Sakamoto ◽  
Ken-ichi Nibu ◽  
Masashi Sugasawa ◽  
Takashi Nakatsuka ◽  
Kiyonori Harii ◽  
...  

Head & Neck ◽  
2014 ◽  
Vol 37 (1) ◽  
pp. 134-150 ◽  
Author(s):  
Primož Strojan ◽  
June Corry ◽  
Avraham Eisbruch ◽  
Jan B. Vermorken ◽  
William M. Mendenhall ◽  
...  

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