scholarly journals Post-Mortem Echocardiography as a Guide to Cardiac Autopsy—A Worthwhile Concept?

2010 ◽  
Vol 4 ◽  
pp. CMC.S5676
Author(s):  
J. Ker ◽  
L. Du Toit-Prinsloo ◽  
WFP. Van Heerden ◽  
G Saayman

Sudden and unexpected death in the young is a common and worldwide problem. Sudden, unexpected death in infancy (SUDI), clinically unexpected death in an infant between one week and one year of age, affects around 1 in 1000 infants. Autopsy will reveal a specific cause of death in only one third of cases. This has led to various ancillary examinations in an effort to increase the diagnostic yield of the autopsy. In this case report it is suggested that another diagnostic modality, that of the post-mortem echocardiogram might be a worthwhile concept to explore.

2014 ◽  
Vol 142 (1-2) ◽  
pp. 94-98 ◽  
Author(s):  
Slobodan Nikolic ◽  
Vladimir Zivkovic

Introduction. Diseases of the gastrointestinal system, and especially diseases of esophagus, are a rare cause of sudden unexpected death in any age group. Black esophagus is an acute necrotizing inflammation of the mucosa of the lower parts of esophagus, diffusely affecting its entire circumference. This inflammation could be a source of profuse bleeding and cause sudden unexpected death. Case Outline. A case of 76-year-old male was presented herein. He has been treated for hypertension and diabetes for several years. As a consequence of stroke, which happened several months prior to death, he had been hemiplegic and immobilized. He died in hospital, suddenly and unexpectedly. The autopsy showed the acute necrotizing esophagitis, as well as the acute gastric and duodenal erosions of mucosa. These were the causes of fatal blood loss. Conclusion. Acute necrotizing esophagitis should be recognized during autopsy and related to the immediate cause of death as well as to concomitant diseases of other organs, which either potentiate or facilitate presentation of this disease.


Author(s):  
Kenan Kaya ◽  
Mete Korkut Gülmen ◽  
Ayşe Serin ◽  
Necmi Çekin ◽  
Ahmet Hilal

Background: Deaths occuring without a known disease and/or a known cause, deaths with non-lethal diseases are interpretated as sudden-unexpected-suspected deaths. Autopsy should always required to evaluate the cause of death. Some of the cases can be termed as negative autopsy since the cause of death can not be determined. This is one of the main interests of the future forensics. Molecular autopsies are one of the main practices of to reduce the negative autopsy ratios. Thus, post-mortem KCNQ1 genetic variation tests are done in sudden unexpected death cases. Material and methods: In this study 0 – 50 years old sudden-unexpected deaths autopsy cases were handled. Samples taken from cases were evaluated and “KCNQ1” genetic variation tests were done in our Department. Results: This study included 47 cases of 42 sudden unexpected death cases (0 – 50 age group) and 5 control group. 15 cases were between 40 – 50 age group and number of cases were increasing with age. 29 of cases (% 69) were male. Evaluation of body-mass index of cases were done and normal weighted cases were the most common with 21 cases (% 50). According to death locations; 17 cases had died (% 45,9) at home. Death location records of 5 cases couldn’t be found. Pathological examinations of all cases were done. We had identified fibrosis and fatty change appearances in SA node of 9 cases (% 21,4) and AV node of 13 cases (% 30,9) especially in conduction tissue examinations. As the result of KCNQ1 genetic analysis of cases, we identified sequence variations in 1638th nucleotid of exon 13 and 1986th nucleotid of exon 16. Conclusion: Cases with conduction system pathology and sequence variations of KCNQ1 genetic analysis shows that we are in need of these tests among routine practice to reduce negative autopsy ratios. Key words: KCNQ1, molecular autopsy, sudden unexpected death, conduction system, negative autopsy.


Visions ◽  
2019 ◽  
pp. 284-290
Author(s):  
Jeanne Donalty

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in people with uncontrolled seizures. This section details the lives of people who have lost a loved one to SUDEP and found meaning from their tragedies by helping others in similar situations.


2013 ◽  
Vol 37 (4) ◽  
pp. 208 ◽  
Author(s):  
Jang-Hee Kim ◽  
Min-Hyung Cho ◽  
Hantai Kim ◽  
Ryun Gil ◽  
Ga-Young Lee ◽  
...  

2005 ◽  
Vol 8 (2) ◽  
pp. 240-244 ◽  
Author(s):  
Chris Wixom ◽  
Amy E. Chadwick ◽  
Henry F. Krous

We report a case of sudden, unexpected death associated with meningioangiomatosis in a 13-year-old, previously healthy male without a history of seizures, neurologic deficits, or clinical stigmata of neurofibromatosis. There was no family history of neurofibromatosis. The postmortem examination showed a 5-cm mass involving the right posterior frontal and orbital frontal cortex that had microscopic features diagnostic of meningioangiomatosis. Because no other cause of death was found, we postulate that he likely died as a result of a seizure secondary to meningioangiomatosis.


2018 ◽  
Vol 71 (11) ◽  
pp. A484
Author(s):  
Robert E. Goldstein ◽  
Margaret L. McCarthy ◽  
Ronald J. Krone ◽  
Mark C. Haigney ◽  
Wojciech Zareba ◽  
...  

2011 ◽  
Vol 14 (1) ◽  
pp. 71-74 ◽  
Author(s):  
Johan Dempers ◽  
Shabbir Ahmed Wadee ◽  
Theonia Boyd ◽  
Colleen Wright ◽  
Hein J. Odendaal ◽  
...  

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