Clinicopathological Features and Outcomes of T- and NK-Cell Lymphomas in European Russia

2012 ◽  
Vol 5 ◽  
pp. CMBD.S7804
Author(s):  
Yulia E. Vinogradova ◽  
Irina B. Kaplanskaya ◽  
Rimma S. Samoilova ◽  
Ivan A. Vorobiev ◽  
Boris V. Zingerman ◽  
...  

With the introduction of the revised World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues in 2001, many patients had to be re-evaluated for the correct diagnosis of T- and NK-cell lymphomas. Because some T-cell malignancies are associated with poor outcome, it is important to identify subsets of patients that may benefit from novel or more intensive therapies. The purpose of this study was to determine, for the first time, the relative frequencies, pathological features and outcomes of patients with T- and NK-cell lymphomas in a predominantly Russian Slavic population. We identified 291 patients with a diagnosis of T- and NK-cell malignancies treated at our Center between 2000-2008. In applying the revised WHO classification, we confirmed the diagnosis and had complete clinical follow up and pathological information on 264 cases that were included in the analysis. We found some differences in frequency of several subsets as compared with previously published reports, including younger age of onset and relatively higher incidence of T-LGL in our patients. We also confirm that intensive treatment regimens of advanced stage PTCL and ALK—ALCL led to considerable improvement in response rates, but not in the overall survival.

Author(s):  
Maria Claudia Nogueira Zerbini ◽  
Fernando Augusto Soares ◽  
Elvira Deolinda Rodrigues Pereira Velloso ◽  
Maria de Lourdes l. F. Chaufaille ◽  
Roberto Pinto Paes

2011 ◽  
Vol 57 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Maria Claudia Nogueira Zerbini ◽  
Fernando Augusto Soares ◽  
Elvira Deolinda Rodrigues Pereira Velloso ◽  
Maria de Lourdes l. F. Chaufaille ◽  
Roberto Pinto Paes

Hemato ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 7-9
Author(s):  
Antonino Carbone

The World Health Organization (WHO) Classification of Tumours of the Hematopoietic and Lymphoid Tissues [...]


2019 ◽  
Vol 21 (4) ◽  
Author(s):  
Isfandari Siti ◽  
Betty Roosihermiatie

Intersectoral approach is essential to develop program for people with disability in Indonesia. Coordination across ministries are necessary to manage this issue. The planning, provision and monitoring of medical and support services as well as program for population groups with disability may require assessment. Purpose of this study is to assess disability in Indonesia. Methods: performing analysis of disability data from 2013 Indonesian Household Health Survey known as Riskesdas. Level of disability obtained from two main population groups: those with and without non communicable disease (NCD). They then divided by age. The World Health Organization Disability Assessment Schedule II (WHODASII) was used to measure disability. Results: contribution of NCD on disability is obvious among older age indicated by higher proportion of disability with NCD. While risk of disability among younger age is unclear, since disability with NCDproportion is lower than disability without NCD. Probably risk of disability among younger age is other than NCD. None of the groups had members with extreme disability on their global WHO-DASII scores. The analysis identifi es target groups for each stakeholder to develop program for people with disability to reach their maximum potential. Abstrak Penanganan penduduk dengan disabilitas membutuhkan keterlibatan lintas kementerian. Diperlukan informasi besar masalah penduduk dengan disabilitas di Indonesia. Analisa bertujuan mengetahui besaran masalah. Metode: analisa deskriptif univariat dan bivariat data disabilitas Riskesdas 2013 untuk memperoleh Informasi disabilitas seluruh penduduk. Selanjutnya dilakukan analisa besaran disabilitas pada penduduk dengan dan tanpa Penyakit Tidak Menular (PTM). Kelompok ini kemudian digolongkan menurut umur. Instrumen The World Health Organization Disability Assessment Schedule II (WHO-DASII) digunakan untuk mengukur disabilitas. Hasil: 18% penduduk Indonesia mengalami disabilitas. Informasi lebih rinci 8,2% mengalami kesulitan ringan, 6,8% kesulitan sedang dan 3% kesulitan berat. Kontribusi PTM terhadap disabilitas terlihat jelas pada kelompok usia 45 tahun atau lebih ditunjukkan dengan lebih tingginya proporsi disabilitas dengan PTM. Sedangkan risiko disabilitas pada kelompok usia sebelum 45 tahun bukan PTM, karena proporsidisabilitas dengan PTM lebih rendah.


2015 ◽  
Vol 37 (2) ◽  
pp. 89-93 ◽  
Author(s):  
D F Gluzman ◽  
L M Sklyarenko ◽  
M Zavelevich ◽  
S V Koval ◽  
T Ivanivskaya ◽  
...  

Exposure to ionizing radiation is associated with increasing risk of various types of hematological malignancies. The results of major studies on association of leukemias and radiation exposure of large populations in Japan and in Ukraine are analyzed. The patterns of different types of leukemia in 295 Chernobyl clean-up workers diagnosed according to the criteria of up-to-date World Health Organization classification within 10–25 years following Chernobyl catastrophe are summarized. In fact, a broad spectrum of radiation-related hematological malignancies has been revealed both in Life Span Study in Japan and in study of Chernobyl clean-up workers in Ukraine. The importance of the precise diagnosis of tumors of hematopoietic and lymphoid tissues according to up-to-date classifications for elucidating the role of radiation as a causative factor of leukemias is emphasized. Such studies are of high importance since according to the recent findings, radiation-associated excess risks of several types of leukemias seem to persist throughout the follow-up period up to 55 years after the radiation exposure.


Background and objective: The increase in obesity amongst adolescents is one of the most important public health concerns in many countries, including the Kingdom of Bahrain. The objective of the current study was to measure the prevalence of overweight and obesity among Bahraini adolescents. This study will aid in a better understanding of the issue and in pursuing preventive measures and campaigns to alleviate the problem. Methods: The weight, height, and body mass index of 9057 Bahraini adolescents was obtained from the Ministry of Health via the nation-wide health electronic file—I-Seha. The final sample consisted of 8463 adolescents; of which 4687 and 3776 were female and males, respectively. References standards from the World Health Organization were used to qualify the adolescents into normal weight, underweight, overweight, obese, and morbidly obese. Results: The overall prevalence of overweight and obesity was 42.3%. Among females the prevalence of overweight and obesity was 21.5% and 20.8%, respectively, whereas in males. the prevalence was 18% and 24.3%, respectively. The lowest prevalence of overweight and obesity was among males aged 15 years (36.4%) and highest among males aged 12 years (47.4%). While in females the prevalence of overweight and obesity was lowest and highest amongst 15-year-olds (38.3%) and 12-year-olds (48.5%). Conclusion: The prevalence of overweight and obesity is high in adolescents in the Kingdom of Bahrain, especially in the younger age group. This increases the urgency to undertake measures to control the problem in the younger population, in order to reduce serious outcomes.


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