scholarly journals Morphoea Profunda Presenting with Atrophic Skin Lesions in a 26 Year Old Female: A Case Report

2012 ◽  
Vol 5 ◽  
pp. CCRep.S9433
Author(s):  
Smith Giri ◽  
Upama Paudel ◽  
Abhimanyu Jha ◽  
Dipendra Gurung ◽  
Sudip Parajuli
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Rare Variant ◽  
Skin Lesions ◽  
Texture Change ◽  
Skin Induration

Morphoea Profunda is a rare variant of Morphoea that presents clinically as a solitary fibrotic plaque. Morphoea Profunda presenting with atrophic lesions has rarely been reported in literature. We report the case of a 26 year old Nepalese lady who presented to us with multiple non-inflammatory atrophic lesions on her body without significant skin induration, pigmentation and texture change. The findings on histopathology confirmed a diagnosis of Morphoea Profunda. Hence, Morphoea Profunda should be considered in the differential diagnosis of anyone presenting with asymptomatic atrophy of the skin.

scholarly journals Cutaneous Manifestations of Toxoplasmosis: a Case Report

2014 ◽  
Vol 6 (3) ◽  
pp. 113-119 ◽  
Author(s):  
Sonya Marina ◽  
Valja Broshtilova ◽  
Ivo Botev ◽  
Dimitrina Guleva ◽  
Maria Hadzhiivancheva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Toxoplasma Gondii ◽  
Complete Resolution ◽  
Skin Lesions ◽  
The Body ◽  
Chemiluminescence Immunoassay ◽  
Cutaneous Manifestations ◽  
Blood Eosinophilia ◽  
The World

Abstract Although toxoplasmosis is one of the most widely spread infections in the world, types that involve the skin are extremely rare. However, skin lesions are not specific; moreover, they are quite diverse, which makes the diagnosis of cutaneous toxoplasmosis rather difficult. Thus, differential diagnosis should include a number of other diseases. We present a case of a 43-year-old immunocompetent man with multiple livid erythematous papules and nodules with yellowish discharge that involved the skin of the body and the extremities. By using electro-chemiluminescence immunoassay, immunoglobulin G antibodies to Toxoplasma gondii were detected in the serum, confirming the diagnosis of toxoplasmosis. The treatment with pyrimethamine and trimethoprim-sulfamethoxazole led to complete resolution of skin lesions. In conclusion, although rare in the dermatological practice, cutaneous toxoplasmosis should be considered in all patients presenting with lymphadenopathy, non-specific skin eruptions, especially nodular and colliquative, blood eosinophilia and histological findigs revealing abundant eosinophilic inflitrations.

Pemphigoid Nodularis

2015 ◽  
Vol 19 (2) ◽  
pp. 153-155 ◽  
Author(s):  
Waleed Al-Salhi ◽  
Ru'aa Alharithy
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Effective Treatment ◽  
Bullous Pemphigoid ◽  
Clinical Features ◽  
Rare Variant ◽  
Early Recognition ◽  
Prurigo Nodularis ◽  
Clinical Variant ◽  
Pemphigoid Nodularis

Background Pemphigoid nodularis is a rare clinical variant of bullous pemphigoid characterized by overlapping clinical features of both prurigo nodularis lesions and bullous pemphigoid blisters. The condition appears to be more common in females and is often resistant to treatment. Objective To raise awareness of this rare variant of bullous pemphigoid. Methods Case report. Results and Conclusion Dermatologists should include this variant in differential diagnosis of prurigo nodularis because early recognition can lead to an effective treatment for the prurigo component.

scholarly journals Remission of Thymoma on Steroid Therapy in a Patient With Atypical Thymoma-Associated Multiorgan Autoimmunity: A Case Report and Literature Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Ewa Wrona ◽  
Sylwia Dębska-Szmich ◽  
Marta Pastuszka ◽  
Marcin Braun ◽  
Rafał Czyżykowski ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
Symptom Management ◽  
Partial Remission ◽  
Skin Lesions ◽  
Humoral Autoimmunity ◽  
Rare Phenomena ◽  
Tumor Remission

In up to 34% of cases, thymoma, itself a rare neoplasm, is accompanied by autoimmune disorders, two of which are thymoma-associated multiorgan autoimmunity (TAMA) and paraneoplastic autoimmune multiorgan syndrome (PAMS). Unfortunately, differential diagnosis between these two entities can be challenging since no strict PAMS definition exists and PAMS can overlap with a subgroup of TAMA patients with skin lesions as leading presentation. We present a case of a 68-year-old woman with a diagnosis of thymoma accompanied by myasthenia gravis, hypothyroidism and GvHD-like mucocutaneous lesions that initially could account to both TAMA and PAMS diagnosis. However, following the exclusion of humoral autoimmunity against components of epithelial cells junction, TAMA was finally established. Interestingly, the introduction of corticosteroid therapy for TAMA symptom management resulted in unexpected partial remission of thymoma with no impact on mucocutaneous lesions. Our case study is an example of two extremely rare phenomena accompanying thymomas: unprecedented TAMA presentation with GvHD-like mucositis, which as we postulate should be placed in the spectrum of TAMA, and tumor remission on steroids.

scholarly journals Cystic fibrohistiocytic tumour of the lung presenting with recurrent pneumothoraces: a case report

2020 ◽  
Vol 90 (3) ◽  
Author(s):  
Christos Kakos ◽  
Savvas Lampridis ◽  
Georgios Geropoulos ◽  
Reena Khiroya ◽  
Achilleas Antonopoulos ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Fibrous Histiocytoma ◽  
Skin Lesions ◽  
Natural Course ◽  
Cystic Lesions ◽  
Fibrous Histiocytomas ◽  
Pulmonary Neoplasm ◽  
History Of

Cystic fibrohistiocytic tumour of the lung is a very rare pathological entity that occurs either as a primary pulmonary neoplasm or as a metastasis from skin lesions called cellular fibrous histiocytomas. Herein, we present the case of a 19-year old man with a history of recurrent pneumothoraces who was managed surgically and was eventually diagnosed with cystic fibrohistiocytic tumour of the lung. Clinicians should include this disease in the differential diagnosis of pulmonary cystic lesions and be aware of its association with cellular fibrous histiocytoma. Reporting of more cases is warranted to further elucidate the natural course of the disease and optimise its management.

Sclerosing Epithelioid Fibrosarcoma: A Case Report

2005 ◽  
Vol 114 (2) ◽  
pp. 87-89 ◽  
Author(s):  
Andrew P. Battiata ◽  
John Casler
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Head And Neck ◽  
Rare Variant ◽  
Head And Neck Neoplasms ◽  
Low Grade ◽  
Oval Cells ◽  
Sclerosing Epithelioid Fibrosarcoma ◽  
Collagenous Tissue ◽  
Mesenchymal Neoplasm

Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of fibrosarcoma. It is a mesenchymal neoplasm composed of round to oval cells dispersed in a nestlike or cordlike distribution on a highly collagenous tissue background and is now recognized as a distinct clinical entity. In this report we discuss the presentation, diagnosis, and treatment of SEF. We focus on the unique histologic and immunohistochemical properties of this lesion. It is essential for both the surgeon and the pathologist to be aware of SEF and include it in the differential diagnosis for atypical head and neck neoplasms. Sclerosing epithelioid fibrosarcoma is a rare neoplasm that is now listed among the low-grade neoplasms that may occur in the head and neck. However, its behavior tends to be typical of more aggressive lesions. An awareness of this characteristic of SEF is essential for clinicians and pathologists alike.

scholarly journals Differential Diagnosis of Post-Procedural Skin Lesions: A Case Report

2016 ◽  
Vol 04 (01) ◽  
pp. 1-4
Author(s):  
Taruna Waghray-Penmetcha ◽  
Sam Li ◽  
Rohit Puranik ◽  
Maria L. Torres
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Skin Lesions

scholarly journals Pemphigus foliaceus as a differential diagnosis in vesicobullous lesions

2017 ◽  
Vol 15 (2) ◽  
pp. 220-222 ◽  
Author(s):  
Louise de Almeida Ferreira Fonseca ◽  
Célia Antônia Xavier de Moraes Alves ◽  
Ivan Aprahamian ◽  
Clóvis Antônio Lopes Pinto
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Clinical Diagnosis ◽  
Clinical Reasoning ◽  
Skin Lesions ◽  
Pemphigus Foliaceus ◽  
Clinical Progression ◽  
Histological Changes ◽  
Clinical Scenarios

ABSTRACT Given the challenge of clinical diagnosis of bullous skin lesions, this report aimed to discuss the histological changes, the presentation and clinical reasoning for diagnosis of these lesions. At the same time, the importance of the pathology was reviewed to identify these clinical scenarios. In this case report, we highlighted the clinical progression of a case of pemphigus foliaceus.

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