scholarly journals Bilateral Carotid Paraganglioma: Surgery and Radiotherapy

2014 ◽  
Vol 7 ◽  
pp. CCRep.S14223 ◽  
Author(s):  
Huriye S. Kiziltan ◽  
Berke Ozucer ◽  
Ali H. Eris ◽  
Bayram Veyseller
Keyword(s):  
Carotid Bifurcation ◽  
Neck Surgery ◽  
Good Alternative ◽  
Vascular Tumors ◽  
Neck Masses ◽  
Shamblin Classification ◽  
Bilateral Carotid ◽  
Painless Mass ◽  
The Right

Background Paragangliomas are relatively rare vascular tumors that develop from the neural crest cells of carotid bifurcation. They usually present as slow-growing, painless unilateral neck masses; bilateral presentation is rare and is mostly associated with familial forms. Bilateral total resection is not always possible for high-grade bilateral tumors, and radiotherapy is a good alternative, with cure rates similar to surgery. Case Report A 35-year-old female patient was admitted with a chief complaint of a bilateral, painless mass located on her neck. Subsequent magnetic resonance imaging (MRI) and angiographic imaging revealed bilateral hypervascular masses surrounding her carotid at 360°, and they were interpreted as stage 3 carotid paragangliomas according to the Shamblin classification protocol. Surgery was carried out on the left carotid paraganglioma and the mass was totally resected. It was thought that the patient could not tolerate bilateral surgery. Primary radiotherapy was planned on the right carotid paraganglioma: 59.8 gray (Gy) conformal, Linac-based multileaf collimator radiotherapy with a 180 cGy daily dosage, and five fractions per week were planned. Results Follow-up at 3 months following the conclusion of radiotherapy revealed no significant regression. A follow-up MRI 6 months and 24 months later revealed 59% regression. Grade 2 esophagitis and minimal neck edema were the only complications noted during the course of radiotherapy and during the 24-month follow-up period. No complications or relapse were observed except for edema following neck surgery.

Fibroadenoma of Ectopic Breast Tissue in the Groin – A Rare Disease Entity

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S47-S48
Author(s):  
D Emechebe ◽  
M Alshal ◽  
T Rana ◽  
M Agaronov
Keyword(s):  
Breast Tissue ◽  
Tissue Mass ◽  
Ectopic Breast Tissue ◽  
The Common ◽  
Painless Mass ◽  
The Right ◽  
Ectopic Breast ◽  
Urogenital Anomalies ◽  
Superficial Soft Tissue

Abstract Introduction/Objective Ectopic breast tissue (EBT) is a well-documented anomaly of the breast and commonly presents along the embryonic milk line extending between the axilla and groin. Reported incidence of accessory breast is 0.4–6% in females. Pathologies developing in an EBT are reported as a rare entity in the literature. Carcinoma is reported as the common pathology followed by inflammation and fibroadenoma Methods We present a case of 43-year- old female who presented with a painless mass in her right groin for the past year which gradually increased in size. CT abdomen pelvis with contrast showed a 2.2 x 3.0 x 4.4 cm superficial soft tissue mass in the right groin which was suspected to be a lymph node. Further investigation and histopathological report of biopsy showed ectopic breast tissue with admixed chronic inflammation and reactive changes.However, excision of the mass three months later showed showed proloferation of both glandular and stromal elements. Results The tissue from the biopsy was positive for GATA 3, mammoglobin, GCDFP and CD 10 and the histological features on excision was confirmatory of fibroadenoma. Conclusion In conclusion, when tumors or nodules are found along the mammary line, the presence of breast tissue should be considered during the investigation. It is clinically wise to evaluate and screen carefully cases of supernumerary breast for any pathology and for any associated urogenital anomalies such as supernumerary kidneys, polycystic kidneys and renal cell adenocaricnoma. In our case, patient had no associated urogenital anomalies and she is on follow up.

scholarly journals Recurrent giant cell tumour of the maxillary sinus and pterygoid process treated with denosumab

2018 ◽  
pp. bcr-2018-225095
Author(s):  
Duarte Rosa ◽  
Raquel Baptista Dias ◽  
João Cunha Salvador ◽  
Alexandra Borges
Keyword(s):  
Maxillary Sinus ◽  
Giant Cell ◽  
Giant Cell Tumour ◽  
Neck Surgery ◽  
Cell Tumour ◽  
Pterygoid Process ◽  
Bone Expansion ◽  
The Right ◽  
Denosumab Treatment

We report the case of a 74-year-old man with a giant cell tumour (GCT) of the right maxilla and pterygoid process. The patient presented to the maxillofacial and head and neck surgery clinic with an ulcerated lesion of the hard palate. Initial workup with CT revealed a mass within the right maxillary sinus and pterygoid process with associated bone expansion and erosion. Biopsy showed a GCT with mucosal ulceration. Two years after surgical resection, a follow-up CT revealed tumour recurrence involving the right pterygoid process and lateral pterygoid muscle. The patient was then proposed for therapy with denosumab. Under denosumab treatment, the lesion maintained stable dimensions and became sclerotic and heavily ossified.

scholarly journals Clinical Characteristics of Nodular Fasciitis of Ear in Children

2021 ◽  
Author(s):  
Xiaoxu Wang ◽  
Wei Liu ◽  
Lejian He ◽  
Min Chen ◽  
Jianbo Shao ◽  
...  
Keyword(s):  
Surgical Resection ◽  
Clinical Characteristics ◽  
Clinical Manifestations ◽  
Neck Surgery ◽  
Final Diagnosis ◽  
Diagnosis And Treatment ◽  
Nodular Fasciitis ◽  
Gene Test ◽  
The Right

Abstract Purpose Summarized the clinical characteristics and diagnosis and treatment process of three cases of nodular fasciitis of ear, to provide a basis for clinical diagnosis and treatment. Methods Reviewed the clinical manifestations, images, pathology, treatment and postoperative follow up results of three cases of pediatric nodular fasciitis in the Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University from 2018 to 2020. Results The average age at diagnosis were 24 months, with two girls and a boy. Two lesions were found in the left ear and one in the right ear. All cases had a history of biopsy before surgery. Two of three cases showed a sign of rapid growth after biopsy and three of which were ineffective in anti-inflammatory treatment. FISH test for USP6 were performed in two of the three cases with positive results. Three lesions show a hypointensity or isointensity on T1-weighted MRI and a heterogeneous hyperintensity on T2-weighted MRI. ‘‘Fascial tail’’ sign was found on image of all three cases. All lesions underwent surgical resection. Follow-up showed no recurrence and had an intact ear appearance. Conclusion The early misdiagnosis rate of nodular fasciitis of the ear is high. Combine clinical features with imaging findings may improve the accuracy of preoperative diagnosis. Besides the appearance of pathology, USP6 gene test is also an important tool in the diagnosis. The final diagnosis should be based on comprehensive assessment. Complete surgical resection can prevent recurrence.

scholarly journals Trichilemmal cyst of the neck: case report and review of the literature

2021 ◽  
pp. 13-17
Author(s):  
Othman El Houari ◽  
Amal Hajjij ◽  
Ilias Tahiri ◽  
Mohamed Said Anajar ◽  
Loubna Taali ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Neck Surgery ◽  
Cervical Region ◽  
Malignant Degeneration ◽  
Review Of The Literature ◽  
Rare Presentation ◽  
Follicular Cyst ◽  
Trichilemmal Cyst ◽  
The Right

Introduction: Trichilemmal cysts are lesions originating in the isthmus of the hair follicle. They are more common in women and occur in 90% on the scalp. Presentation of case: A 10-year-old female patient presented with a hard, slightly painful, nonexophytic mass in the right cervical region (Ia). After surgical resection in healthy margins, the diagnosis of trichilemmal cyst was made on histopathological examination. Discussion: The age of the patient as well as the cervical location of this type of lesion is an extremely rare presentation of trichilemmal cyst. Follow-up is rigorous in search of a triad: ichthyosis, keratosis, deafness, particularly in this patient. Conclusion: Close follow-up in this clinical case is indicated because the risk of malignant degeneration and development of similar lesions is present. Keywords: Follicular cyst; KID syndrome; Trichilemmal cyst; Neck surgery; Trichilemmal carcinoma

scholarly journals FOREFOOT MYOPERICYTOMA: A CASE REPORTAND REVIEW OF THE LITERATURE

2021 ◽  
Vol 9 (4) ◽  
pp. 859-862
Author(s):  
Fahd Idarrha ◽  
Youness Aznague ◽  
Yassine Fathlkhir ◽  
Brahim Demnati ◽  
Abass Guedi Omar ◽  
...  
Keyword(s):  
Smooth Muscle Actin ◽  
Dorsal Surface ◽  
Growth Patterns ◽  
Malignant Neoplasms ◽  
Unique Case ◽  
X Ray ◽  
Painless Mass ◽  
The Right ◽  
Rare Group

Background:Myopericytoma (MPC) is term that describe a rare group of perivascular tumours of soft tissue and show a range of histological growth patterns. Only a few cases describing MPC have been reported. Aims: To document and investigate the clinical and histopathological characteristics and differential diagnosis of myopericytoma. Patients/methods: The present study reports a unique case of myopericytomas found in the 2nd and 3rd inter-toe spaces of a 54-year-old patient. Results: a 54 year old female patient, presents in our department for a painless mass on the dorsal surface of the right forefoot of progressive installation over 2 years.The mass was firm, non pulsatile and mobile, with no sign of inflammation, evolving in a context of conservation of the general state. The X-ray of the right forefoot did not reveal any notable bone abnormality. An MRI was subsequently performed, which objectified an infiltrating tumor mass of probable sarcomatous origin. The mass was excised surgically, and a pathological and immunohistochemical examination was performed afterward, the diagnosis of myopericytoma was confirmed. No recurrence was found in the follow-up of 12 months. Conclusions: MPC is a rare and mostly benign tumor that presents as spindle cells in a concentric perivascular growth model with an immunohistochemical staining positive for smooth muscle actin. Local recurrences and rarely metastases may occur in atypical and malignant neoplasms.

scholarly journals Spontaneous Hyphema from Iris Microhemangiomatosis in an Elderly Patient with Hypertensive Crisis

2020 ◽  
Vol 11 (1) ◽  
pp. 68-72
Author(s):  
Pedro J.  Nuova ◽  
Dinah Zur ◽  
Anat Loewenstein ◽  
Matias Iglicki
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Hypertensive Crisis ◽  
Anterior Segment ◽  
Rare Condition ◽  
Vascular Tumors ◽  
Recurrent Bleeding ◽  
Iris Neovascularization ◽  
The Right

Background: Iris microhemangiomatosis is a rare vascular iris tumor, with potential severe complications such as increased intraocular pressure (IOP). We aim to describe a case report of a patient presenting with hyphema secondary to iris microhemangiomatosis triggered by excessive high blood pressure. Case Presentation: A 74-year-old woman was treated for hypertensive crisis. After her high blood pressure had been controlled and stabilized, she was discharged home. However, the same day, she complained about an acute decrease in vision in her left eye. Best corrected visual acuity was 20/20 on the right eye and 20/200 on the left eye. On biomicroscopy, a hyphema was seen. Iris neovascularization was absent, IOP and fundus examination were normal. After spontaneous resolution of the hyphema, a fluorescein angiography of the anterior segment was performed, which revealed bilateral subtle early hyperfluorescence with late staining scattered at the pupillary margin. The patient was diagnosed with iris microhemangiomatosis. During the follow-up of 24 months, the blood pressure was stable and well controlled. The patient did not experience any recurrent hemorrhage. Discussion and Conclusion: Spontaneous hyphema is the most common complication of iris vascular tumors. We report the occurrence of a spontaneous hyphema triggered by uncontrolled blood pressure in a patient with a very rare condition, i.e., iris microhemangiomatosis. In order to avoid complications of microhemangiomatosis such as uncontrolled glaucoma or recurrent bleeding requiring surgery, blood pressure should be monitored closely and controlled.

scholarly journals Panoramic radiography for detection of bilateral carotid calcified atheroma: An unusual Case Report

2020 ◽  
Vol 9 (6) ◽  
pp. 511-515
Author(s):  
Maximiliano Bravo-Valenzuela ◽  
◽  
Javiera Reyes-Velásquez ◽  
Salvador Valladares-Pérez ◽  
◽  
...  
Keyword(s):  
Case Report ◽  
Carotid Arteries ◽  
Unusual Case ◽  
Panoramic Radiography ◽  
Catholic University ◽  
Atheromatous Plaques ◽  
Bilateral Carotid ◽  
Complementary Resource ◽  
The Right

Introduction: Atherosclerosis is a progressive inflammatory disease that can trigger serious medical consequences like acute myocardial infarction or stroke. Case Report: The purpose of this study is to report an unusual case of finding calcified atheromatous plaques in the carotid arteries bilaterally using a panoramic radiography (PR). A 75-year-old female with a morbid history, attends the Teaching Dental Clinic of the Pontifical Catholic University with complementary exams. PR showed well-defined radiopaque structures adjacent to C4. Using a Doppler ultrasound, the presence of calcified atheromas in the right and left carotid arteries were confirmed. The patient was informed of these findings and is currently under medical follow-up. Conclusion: PR is a useful complementary resource in the detection of atherosclerotic plaques of the upper carotid region.

scholarly journals Bilateral carotid and vertebral arterial dissection after vaccine for COVID-19: case report

2021 ◽  
Author(s):  
Gustavo Humberto Webber ◽  
Gabriel Cavalheiro Lessack ◽  
Felipe Ibiapina dos Reis
Keyword(s):  
Case Report ◽  
Internal Carotid ◽  
Arterial Dissection ◽  
Vascular Endothelial ◽  
Vertebral Arteries ◽  
Antiplatelet Aggregation ◽  
Bilateral Carotid ◽  
The Right ◽  
Sudden Headache

Context: This case report describes a patient with bilateral dissection of the carotid and vertebral arteries after being immunized by the Astrazeneca vaccine against COVID-19. Case report: AVC, female, 55 years old, health professional, without previous illness, received ChAdOx1 nCov-19 AstraZeneca vaccine and evolved after one day with flu-like symptoms, headache, odynophagia, fever, myalgia for 5 days. On the 7th day, she sought hospital service complaining of sudden headache, and numbness in the left upper limb. A non-reactive Sars-Cov-2 RT-PCR test was performed. The patient was released after clinical improvement. She returned after 8 days, being diagnosed with migraine and was treated with sintomatic drugs. After more 7 days, during the neurologist appointment, she reported daily headaches of varying intensity and episodes of unverified fever, with no findings on physical examination. Laboratory tests, brain resonance with cranial and cervical angioresonance, which showed findings of bilateral carotid dissection, involving the supra-bulbar segments of both internal carotid arteries, notably in the right internal carotid artery, as well as degrees of dissection of both vertebral arteries. On admission, antiplatelet aggregation was chosen, with the patient showing good evolution and being discharged after 4 days for outpatient follow-up. Conclusion: The patient has no evident risk factor for arterial dissection. In addition, the post-vaccine adverse reaction and the temporal gap between the application of the vaccine and the development of multiple arterial dissections drew attention. A possible link between the patient’s immune response and vascular endothelial inflammatory reaction is suggested, resulting in multiple arterial dissections.

scholarly journals Bilateral sixth nerve palsies from carotid cavernous fistulas with transient worsening following transvenous embolisation

2019 ◽  
Vol 12 (11) ◽  
pp. e232191
Author(s):  
Sivaruben Kalaichandran ◽  
Jonathan A Micieli
Keyword(s):  
Good Prognosis ◽  
Double Vision ◽  
Similar Treatment ◽  
Bilateral Carotid ◽  
History Of ◽  
The Right ◽  
Carotid Cavernous Fistulas ◽  
Onyx Embolisation ◽  
Sixth Nerve

A 59-year-old man presented with a 2-week history of binocular horizontal diplopia worse when looking to the left. He was diagnosed with a left sixth nerve palsy (6 NP) and had new bilateral findings at a 2-week follow-up with new dilated episcleral blood vessels. Bilateral carotid-cavernous fistulas (CCFs) were suspected and confirmed with CT angiography and catheter angiography. He underwent successful coil and Onyx embolisation of the left cavernous sinus and immediately noticed worsening of the double vision when looking left due to a worse left 6 NP. Three weeks later, he underwent similar treatment of the right CCF and immediately noticed worsening of the double vision when looking to the right and was found to have a worse right 6 NP. His double vision resolved 6 months later. CCFs are rare causes of bilateral 6 NPs and although there is a good prognosis, symptoms may worsen after treatment.

scholarly journals Nodular Fasciitis With Malignant Morphology and a COL6A2–USP6 Fusion: A Case Report (of a 10-Year-old Boy)

2021 ◽  
pp. 106689692199604
Author(s):  
Tess Tomassen ◽  
Cees van de Ven ◽  
Jakob Anninga ◽  
Christian Koelsche ◽  
Laura S. Hiemcke-Jiwa ◽  
...  
Keyword(s):  
Benign Lesion ◽  
Nodular Fasciitis ◽  
Mesenchymal Neoplasm ◽  
Specific Protease ◽  
History Of ◽  
Mitotic Figures ◽  
Painless Mass ◽  
The Right

Nodular fasciitis is usually a benign lesion genetically characterized by ubiquitin-specific protease 6 ( USP6) rearrangements. We present a case of a 10-year-old boy with a 1.5-week history of a painless mass on the right chest wall, which was excised. A histomorphologically malignant tumor with pronounced pleomorphism, atypical mitotic figures, and a myoid immunophenotype was observed. The methylation profile was consistent with nodular fasciitis and fluorescence in situ hybridization confirmed USP6 rearrangement. Using Archer Fusion Plex (Sarcoma Panel) and RNA sequencing, a collagen, type VI, alpha 2 ( COL6A2) –USP6 gene fusion was subsequently identified. Furthermore, DNA clustering analysis also showed a match with nodular fasciitis. During the follow-up of 22 months, no recurrence or metastasis occurred. In conclusion, we describe a clinically benign, histomorphologically malignant mesenchymal neoplasm with a myoid immunophenotype, and a genetic and epigenetic profile consistent with nodular fasciitis. In such cases, molecular analysis is a useful adjunct to avoid unnecessary overtreatment.

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