scholarly journals MicroRNA-155 and Its Role in Malignant Hematopoiesis

2015 ◽  
Vol 10 ◽  
pp. BMI.S27676 ◽  
Author(s):  
Prajnya Ranganath
Keyword(s):  
B Cell ◽  
Molecular Interactions ◽  
Therapeutic Target ◽  
Hematological Malignancies ◽  
B Cell Lymphomas ◽  
Large B Cell

MicroRNA-155 (miR-155) is a multifunctional molecule involved in both normal and malignant hematopoiesis. It has been found to be involved in the pathogenesis of many different hematological malignancies with either an oncogenic or a tumor-repressor effect, depending on the nature of the cell and the type of malignancy. In particular, it has been strongly implicated in the causation of diffuse large B-cell lymphomas. This review focuses on the molecular interactions of miR-155, its oncogenic mechanisms, and its potential as an effective therapeutic target for the associated malignancies.

Management Of Elderly Patients With Diffuse Large B-Cell Lymphomas

2013 ◽  
Vol 13 (9) ◽  
pp. 1412-1418 ◽  
Author(s):  
Rosanna Ciancia ◽  
Umberto Tirelli ◽  
Josep-Maria Ribera ◽  
Michele Spina
Keyword(s):  
Elderly Patients ◽  
B Cell ◽  
B Cell Lymphomas ◽  
Large B Cell

Lack of expression of LMO2 clone SP51 identifies MYC rearrangements in aggressive large B-cell lymphomas

2021 ◽  
Author(s):  
Ivonne Vazquez ◽  
Natalia Papaleo ◽  
Joan Lop ◽  
Anna Puiggros ◽  
Blanca Sanchez-Gonzalez ◽  
...  
Keyword(s):  
B Cell ◽  
B Cell Lymphomas ◽  
Large B Cell

scholarly journals OP0108 Aggressive lymphomas (diffuse large b cell lymphomas) are overrepresented in ra patients

2001 ◽  
Author(s):  
E Baecklund ◽  
C Sundström ◽  
A Ekbom ◽  
N Feltelius ◽  
L Klareskog
Keyword(s):  
B Cell ◽  
B Cell Lymphomas ◽  
Aggressive Lymphomas ◽  
Large B Cell

scholarly journals Among diffuse large B-cell lymphomas, T-cell-rich/histiocyte-rich BCL and CD30 + anaplastic B-cell subtypes exhibit distinct clinical features

2001 ◽  
Vol 12 (6) ◽  
pp. 853-858 ◽  
Author(s):  
B. Maes ◽  
A. Anastasopoulou ◽  
J.C. Kluin-Nelemans ◽  
I. Teodorovic ◽  
R. Achten ◽  
...  
Keyword(s):  
T Cell ◽  
B Cell ◽  
Clinical Features ◽  
B Cell Lymphomas ◽  
Large B Cell

scholarly journals CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas

Haematologica ◽  
2019 ◽  
Vol 105 (5) ◽  
pp. 1361-1368 ◽  
Author(s):  
Linfeng Chen ◽  
Jing Ouyang ◽  
Kirsty Wienand ◽  
Kamil Bojarczuk ◽  
Yansheng Hao ◽  
...  
Keyword(s):  
B Cell ◽  
Resistance Mechanism ◽  
Cell Receptor ◽  
B Cell Receptor ◽  
B Cell Lymphomas ◽  
Large B Cell

scholarly journals A Subset of CD5– Diffuse Large B-Cell Lymphomas Expresses Nuclear Cyclin D1 With Aberrations at theCCND1Locus

2008 ◽  
Vol 129 (4) ◽  
pp. 630-638 ◽  
Author(s):  
Mats Ehinger ◽  
Johan Linderoth ◽  
Birger Christensson ◽  
Birgitta Sander ◽  
Eva Cavallin-Ståhl
Keyword(s):  
B Cell ◽  
Cyclin D1 ◽  
B Cell Lymphomas ◽  
Large B Cell
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