scholarly journals Bioremediation of Benzophenone by Glycosylation with Immobilized Marine Microalga Chrysocampanulla spinifera and Amphidinium crassum

2011 ◽  
Vol 4 ◽  
pp. BCI.S8212
Author(s):  
Kei Shimoda ◽  
Yushi Uchimura ◽  
Hiroya Imai ◽  
Megumi Kitagawa ◽  
Hirotaka Hirano ◽  
...  
Keyword(s):  
Catharanthus Roseus ◽  
Plant Cells ◽  
The Other ◽  
Endocrine Disrupting Chemical ◽  
Marine Microalga ◽  
Other Hand ◽  
Endocrine Disrupting ◽  
One Step ◽  
Immobilized Plant Cells

Reduction and glycosylation of benzophenone, which is an endocrine disrupting chemical, were investigated using immobilized marine microalga and plant cells from the viewpoint of bioremediation of benzophenone. Immobilized marine microalga of Chrysocampanulla spinifera reduced benzophenone to diphenylmethanol. Immobilized marine microalga of Amphidinium crassum glucosylated diphenylmethanol to the corresponding glucoside. The sequential biotransformation with C. spinifera and A. crassum effectively converted benzophenone into diphenylmethyl glucoside. On the other hand, immobilized plant cells of Catharanthus roseus transformed benzophenone to diphenylmethanol, diphenylmethyl glucoside, and diphenylmethyl primeveroside, which was a new compound, by one-step biotransformation.

scholarly journals Glucosylation of Taxifolin with Cultured Plant Cells

2013 ◽  
Vol 8 (7) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Kei Shimoda ◽  
Naoji Kubota ◽  
Manabu Hamada ◽  
Masahiro Sugamoto ◽  
Kohji Ishihara ◽  
...  
Keyword(s):  
Nicotiana Tabacum ◽  
Catharanthus Roseus ◽  
Cultured Cells ◽  
Plant Cells ◽  
The Other ◽  
Other Hand

Cultured plant cells of Eucalyptus perriniana glucosylated taxifolin to its 3′- and 7- O-β-D-glucosides and 3′,7- O-β-D-diglucoside. On the other hand taxifolin was converted into 3′- and 7- O-β-D-glucosides by cultured cells of Nicotiana tabacum and Catharanthus roseus.

scholarly journals Synthesis of Resveratrol Glycosides by Cultured Plant Cells

2013 ◽  
Vol 8 (7) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Kei Shimoda ◽  
Manabu Hamada ◽  
Hatsuyuki Hamada ◽  
Mai Takemoto ◽  
Hiroki Hamada
Keyword(s):  
Glycine Max ◽  
Cultured Cells ◽  
Plant Cells ◽  
The Other ◽  
Other Hand

Incubation of cultured cells of Glycine max with trans-resveratrol gave its 3-O-β-D- and 4′- O-β-D-glucosides. Cultured Gossypium hrsutum cells glycosylated trans-resveratrol to its 3-O-β-D-, 4′- O-β-D- and 3,4′- O-β-D-diglucosides. On the other hand trans-resveratrol was converted into cis-resveratrol 4′- O-β-D-glucoside together with trans-resveratrol 3- O-β-D-glucoside and trans-resveratrol 4′- O-β-D-glucoside by Eucalyptus perriniana.

scholarly journals Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants

2021 ◽  
Vol 12 ◽  
Author(s):  
Rafael Bayarri-Olmos ◽  
Ida Jarlhelt ◽  
Laust Bruun Johnsen ◽  
Cecilie Bo Hansen ◽  
Charlotte Helgstrand ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Convergent Evolution ◽  
Binding Domain ◽  
Viral Fitness ◽  
The Other ◽  
Receptor Binding Domain ◽  
Gain Of Function ◽  
Other Hand ◽  
One Step

The recent identification and rise to dominance of the P.1 and B.1.351 SARS-CoV-2 variants have brought international concern because they may confer fitness advantages. The same three positions in the receptor-binding domain (RBD) are affected in both variants, but where the 417 substitution differs, the E484K/N501Y have co-evolved by convergent evolution. Here we characterize the functional and immune evasive consequences of the P.1 and B.1.351 RBD mutations. E484K and N501Y result in gain-of-function with two different outcomes: The N501Y confers a ten-fold affinity increase towards ACE-2, but a modest antibody evasion potential of plasma from convalescent or vaccinated individuals, whereas the E484K displays a significant antibody evasion capacity without a major impact on affinity. On the other hand, the two different 417 substitutions severely impair the RBD/ACE-2 affinity, but in the combined P.1 and B.1.351 RBD variants, this effect is partly counterbalanced by the effect of the E484K and N501Y. Our results suggest that the combination of these three mutations is a two-step forward and one step back in terms of viral fitness.

Network Based Fusion of Global and Local Information in Time Series Prediction with the Use of Soft-Computing Techniques

2010 ◽  
pp. 176-196
Author(s):  
Shun-Feng Su ◽  
Sou-Horng Li
Keyword(s):  
Time Series ◽  
Time Series Prediction ◽  
The Other ◽  
Good Prediction ◽  
Model Free ◽  
Local Prediction ◽  
Other Hand ◽  
Prediction Scheme ◽  
One Step ◽  
The One

Forecasting data from a time series is to make predictions for the future from available data. Thus, such a problem can be viewed as a traditional data mining problem because it is to extract rules for prediction from available data. There are two kinds of forecasting approaches. Most traditional forecasting approaches are based on all available data including the nearest data and far away data with respect to the time. These approaches are referred to as the global prediction scheme in our study. On the other hand, there also exist some prediction approaches that only construct their prediction model based on the most recent data. Such approaches are referred to as the local prediction schemes. Those local prediction approaches seem to have good prediction ability in some cases but due to their local characteristics, they usually fail in general for long term prediction. In this chapter, the authors shall detail those ideas and use several commonly used models, especially those model free estimators, such as neural networks, fuzzy systems, grey systems, etc., to explain their effects. Another issues discussed in the chapter is about multi-step predictions. From the author’s study, it can be found that those often-used global prediction schemes can have fair performance in both one-step-ahead predictions and multi-step predictions. On the other hand, good local prediction schemes can have better performance in the one-step-ahead prediction when compared to those global prediction schemes, but usually have awful performance for multi-step predictions. In this chapter, the authors shall introduce several approaches of combining local and global prediction results to improve the prediction performance.

Quantum period finding based on the Bernstein-Vazirani algorithm

2020 ◽  
Vol 20 (1&2) ◽  
pp. 65-84
Author(s):  
Xuexuan Hao ◽  
Fengrong Zhang ◽  
Yongzhuang Wei ◽  
Yong Zhou
Keyword(s):  
Polynomial Time ◽  
Quantum Memory ◽  
The Other ◽  
Symmetric Cryptography ◽  
Grover’S Algorithm ◽  
Key Recovery ◽  
Other Hand ◽  
Vectorial Function ◽  
One Step ◽  
Key Recovery Attack

Quantum period finding algorithms have been used to analyze symmetric cryptography. For instance, the 3-round Feistel construction and the Even-Mansour construction could be broken in polynomial time by using quantum period finding algorithms. In this paper, we firstly provide a new algorithm for finding the nonzero period of a vectorial function with O(n) quantum queries, which uses the Bernstein-Vazirani algorithm as one step of the subroutine. Afterwards, we compare our algorithm with Simon's algorithm. In some scenarios, such as the Even-Mansour construction and the function satisfying Simon's promise, etc, our algorithm is more efficient than Simon's algorithm with respect to the tradeoff between quantum memory and time. On the other hand, we combine our algorithm with Grover's algorithm for the key-recovery attack on the FX construction. Compared with the Grover-Meets-Simon algorithm proposed by Leander and May at Asiacrypt 2017, the new algorithm could save the quantum memory.

Glycosylation of Quercetin with Cultured Plant Cells and Cyclodextrin Glucanotransferase

2014 ◽  
Vol 9 (5) ◽  
pp. 1934578X1400900
Author(s):  
Kei Shimoda ◽  
Naoji Kubota ◽  
Manabu Hamada ◽  
Daisuke Uesugi ◽  
Masato Tanigawa ◽  
...  
Keyword(s):  
Ipomoea Batatas ◽  
Plant Cells ◽  
The Other ◽  
Cyclodextrin Glucanotransferase ◽  
Other Hand

Quercetin was glucosylated by cultured plant cells of Ipomoea batatas to its 3- and 7- O-β-D-glucosides, and 3,7- O-β-D-diglucoside. On the other hand, further glycosylation of quercetin 3-O-β-D-glucoside by cyclodextrin glucanotransferase gave the 3-O-β-maltoside, 3-O-β-maltotrioside, and 3-O-β-maltotetraosides of quercetin.

scholarly journals Regioselective hydroxylation and dehydrogenation of capsaicin and dihydrocapsaicin by cultured cells of Phytolacca americana

2021 ◽  
Vol 85 (1) ◽  
pp. 103-107
Author(s):  
Kei Shimoda ◽  
Tsubasa Ono ◽  
Hiroki Hamada
Keyword(s):  
Cultured Cells ◽  
Plant Cells ◽  
Suspension Cultures ◽  
The Other ◽  
Phytolacca Americana ◽  
Other Hand ◽  
Regioselective Hydroxylation ◽  
First Time

Abstract The biotransformations of capsaicin and dihydrocapsaicin were investigated using cultured plant cells of Phytolacca americana as biocatalysts. Four products, ie 15-hydroxycapsaicin, dihydrocapsaicin, 15-hydroxydihydrocapsaicin, and capsaicin 4-β-glucoside, were isolated from the suspension cultures of P. americana treated with capsaicin for 3 days, showing that capsaicin was regioselectively hydroxylated, reduced, and glucosylated by cultured P. americana cells. On the other hand, dihydrocapsaicin was regioselectively dehydrogenated, hydroxylated, reduced, and glucosylated to give four products, ie capsaicin, 15-hydroxycapsaicin, 15-hydroxydihydrocapsaicin, and capsaicin 4-β-glucoside, by cultured P. americana cells. In this paper, it is reported, for the first time, that dihydrocapsaicin is converted into 15-hydroxydihydrocapsaicin by plant cultured cells.

scholarly journals Gender and Digital Public Relations: Who Gets Benefits?

2021 ◽  
Vol 13 (1) ◽  
pp. 108-122
Author(s):  
Nobertus Ribut Santoso
Keyword(s):  
Public Relations ◽  
The Other ◽  
Good Communication ◽  
Public Relations Practitioners ◽  
Digital Era ◽  
Other Hand ◽  
Organizational Activity ◽  
Managerial Roles ◽  
One Step ◽  
Massive Development

Public relations professionals have been dominated by females since they have good communication skills and abilities in persuading and engaging in the conversation and listening the stakeholders to build and harmonize relationships them. However, male public relations practitioners dominate in the top positions since they have been participated in the managerial roles while female are in the technical roles. In the organization, female public relations practitioners face inequalities in social, professional, and economic areas and they also find it difficult to achieve higher position because the traditional patriarchy is still strongly practiced. It harder for them to break this barrier. Family and children, on the other hand, become big considerations for females to climb the higher position since it will give bigger responsibilities. Moreover, the massive development of digital technologies provides more opportunities for female public relations professionals to intensively engage with the stakeholders. On the other hand, these technologies bring privilege for males since they are more digital technical skills. To compete with males in digital public relations, females should enhance their digital skills, wisely manage their time, learn to take new challenges making them one step ahead, and actively participate in every organizational activity to voice their ideas and straighten up false assumptions and misconceptions about females.  Meanwhile, males should be versatile public relations professionals in the digital era by combining masculine and feminine values to find the best public relations practices.

scholarly journals Chronic efffects of bisphenol an exposure on zebrafish (Danio rerio) at juvenile state

2019 ◽  
Vol 3 (1) ◽  
pp. 37-45
Author(s):  
Mai Thi Ngo ◽  
Phuong Thao Thi Doan ◽  
Ngoc Diem Thi Vo ◽  
Cong Thanh Nguyen ◽  
Nga Phi Le
Keyword(s):  
Natural Waters ◽  
Growth Period ◽  
The Other ◽  
Food Storage ◽  
Endocrine Disrupting Chemical ◽  
Hepatic Cells ◽  
Endocrine Disrupting ◽  
Plastic Toys ◽  
Plastic Containers ◽  
Nuclear Enlargement

Introduction: Bisphenol A (BPA) is an endocrine disrupting chemical, therefore some countries have banned the use of it in plastic containers for food storage and plastic toys for children. BPA can be found in natural waters with measured concentrations varying from ng/l to mg/l. However, in fact that the chronic ecotoxicology data obtained from aquatic animals for BPA exposure at these levels are quite few. Methods: In this study zebrafish at 30 days of age were exposed to four variants 0, 1, 10 and 100 μg/l BPA along 60 days, which is the fasted growth period in zebrafish (Juvenile stage). At the end of the experiments, all fish weight and length were measured and their fresh livers were used for histological assessment. Results: The results showed that weight and length of fish in 100 mg/l BPA group increased significantly as compared with that in the other experimental groups. Also only in this group, changes in hepatic morphology such as vacuolar number and size increasement, cytoplasmicand/or nuclear enlargement, glycogen reduction, lipid enhancement, were observed, but especially no significant inflammation. Fish in the other groups exposed to BPA concentrations <100mg/l had no change in all targeted endpoints as compared with that of the control. Conclusion: Chronic exposure of 100mg/L BPA to zebrafish along the fast-growth period (Juvenile) caused increasement of weight and length, and altered morphology of hepatic cells, that may harm to liver functions.  

scholarly journals L'abus de pouvoirs du mandataire en droit civil québécois

2005 ◽  
Vol 19 (1) ◽  
pp. 55-103
Author(s):  
Claude Fabien
Keyword(s):  
Civil Code ◽  
Third Parties ◽  
The Other ◽  
Conservative Approach ◽  
Other Hand ◽  
One Step

The purpose of this article is to study the rules governing the phenomenon of mandatories abusing their powers, under Quebec Civil Code. It also reviews the rules proposed by the Civil Code Revision Office in its 1971 and 1976 Reports on the contract of Mandate and in its 1976 Report on administration of property of others. It shows that on many issues the Office has chosen a rather conservative approach and decided to stick to time-proven rules. It also flags the areas where the Office advocates new rules, with appropriate comments. The article is divided in two parts, the first one dealing with the scope of abuse of powers, the second with its effects. Part one asks « When does a mandatory abuse his powers ? » and answers by distinguishing between the wrongful exercise of mandatory's actual powers and the exercise, right or wrong, of non-existant powers. Part two then asks « What are the effects of abuses of powers ? » and deals on one hand with the liability towards third parties of both mandators and mandatories, and on the other hand with the liability of mandatories towards their mandators. The interest of part one lies mainly with the distinction it makes between two types of abuses of powers and with the analysis of the remarkable contribution of the Report on administration of the property of others into the field of Mandate. Part two derives its interest from the study of rules aimed at protecting third parties against abuses of powers of mandatories, and from testing the relevance of distinguishing between two types of abuses of powers. One conclusion, among others, emerges from this article. Mandators are fully liable towards third parties when mandatories abuse their powers by using them wrongfully. Conversely mandators are not liable when mandatories abuse their powers by using non-existant powers, although this principle suffers exceptions numerous enough to constitute a genuine regime of protections for third parties against self-empowered mandatories. The article suggests however that Quebec Law could go one step further by improving protection of third parties under the existing notion of apparent mandate, especially for those dealing with companies.

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