scholarly journals Identification of Breast Cancer-Associated Lipids in Scalp Hair

2012 ◽  
Vol 6 ◽  
pp. BCBCR.S9607 ◽  
Author(s):  
Dharmica A.H. Mistry ◽  
Joseph Haklani ◽  
Peter W. French
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Biological Samples ◽  
Molecular Mechanisms ◽  
Scalp Hair ◽  
Breast Cancer Patients ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray

A correlation between the presence of breast cancer and a change in the synchrotron-generated X-ray diffraction (XRD) pattern of hair has been reported in several publications by different groups, and on average XRD-based assays detect around 75% of breast cancer patients in blinded studies. To date, the molecular mechanisms leading to this alteration are largely unknown. We have determined that the alteration is likely to be due to the presence of one or more breast cancer-associated phospholipids. Further characterization of these lipids could be used to develop a novel, sensitive and specific screening test for breast cancer, based on hair initially, and potentially extendable to other biological samples.

Trace element abnormalities in the scalp hair of breast cancer patients

2014 ◽  
Vol 24 (01n02) ◽  
pp. 49-58 ◽  
Author(s):  
Z. Kabiri ◽  
O. Kakuee ◽  
V. Fathollahi ◽  
B. Stout
Keyword(s):  
Breast Cancer ◽  
Trace Elements ◽  
Trace Element ◽  
Cancer Patients ◽  
Scalp Hair ◽  
Healthy Controls ◽  
Meaningful Difference ◽  
Breast Cancer Patients ◽  
X Ray ◽  
Significant Difference

Development of a number of diseases like cardiovascular diseases and cancer has been related with abnormalities of certain trace elements in some tissues. The purpose of this study was to investigate the levels of trace elements in breast cancer patients in comparison with healthy controls. Particle induced X-ray emission (PIXE) technique was employed to measure the hair trace element concentrations in 30 cancer patients and 30 healthy controls. A 2.2 MeV proton beam was employed to excite the biological samples. The concentrations of Fe and Cu ([Formula: see text]) in the hair of cancer patients were found to be higher compared to those of healthy controls, while the concentration of Zn ([Formula: see text]) was found to be lower. No significant difference was observed for sulfur concentration between the two groups. Also, no meaningful difference was observed in the concentrations of K, Ca, Ti as well as ratios of Cu/Zn and Cu/Fe in the hair of the two groups ([Formula: see text]). These abnormalities could potentially be used as a means of breast cancer screening in women.

High Resolution Replication of Organoclay Surfaces

1982 ◽  
Vol 40 ◽  
pp. 576-577
Author(s):  
W. W. Barker ◽  
W. E. Rigsby ◽  
V. J. Hurst ◽  
W. J. Humphreys
Keyword(s):  
Clay Mineral ◽  
Organic Molecule ◽  
Organic Molecules ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Naturally Occurring ◽  
Silicate Layers ◽  
Mineral Identification

Experimental clay mineral-organic molecule complexes long have been known and some of them have been extensively studied by X-ray diffraction methods. The organic molecules are adsorbed onto the surfaces of the clay minerals, or intercalated between the silicate layers. Natural organo-clays also are widely recognized but generally have not been well characterized. Widely used techniques for clay mineral identification involve treatment of the sample with H2 O2 or other oxidant to destroy any associated organics. This generally simplifies and intensifies the XRD pattern of the clay residue, but helps little with the characterization of the original organoclay. Adequate techniques for the direct observation of synthetic and naturally occurring organoclays are yet to be developed.

Hydrothermal Synthesis and Characterization of BiFeO3 Polyhedral Crystallites

2012 ◽  
Vol 174-177 ◽  
pp. 508-511
Author(s):  
Lin Lin Yang ◽  
Yong Gang Wang ◽  
Yu Jiang Wang ◽  
Xiao Feng Wang
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Synthesis And Characterization ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Transmission Electron ◽  
Scanning Electron

BiFeO3 polyhedrons had been successfully synthesized via a hydrothermal method. The as-prepared products were characterized by power X-ray diffraction (XRD) pattern, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The possible mechanisms for the formation of BiFeO3 polyhedrons were discussed. Though comparison experiments, it was found that the kind of precursor played a key role on the morphology control of BiFeO3 crystals.

scholarly journals An observational study of post-operative Volumetric Modulated Arc Radiotherapy (VMAT) of breast cancer by immobilizing patients on All-in-one (AIOTM) solution Breast and Lung Board without usingthermoplastic mask: Risk of collusion of gantry with couch exists if acquisition of Cone-beam Computed Tomography (CBCT)is attempted for set-up verification.

2020 ◽  
Author(s):  
Ramaiah Vinay Kumar
Keyword(s):  
Breast Cancer ◽  
Computed Tomography ◽  
Cancer Patients ◽  
Target Volume ◽  
Cone Beam ◽  
Breast Cancer Patients ◽  
Unilateral Breast Cancer ◽  
Planar Image ◽  
X Ray ◽  
Set Up

Abstract Background: Automatic Cone-beam computed tomography (CBCT) based image matching for set-up verification is recommended as compared to 2-D match for post-operative local / loco-regional radiotherapy of breast cancer patients by Volumetric Modulated Arc Therapy (VMAT) technique. However, in supine position, off-midline peripheral body Clinical Target Volume (CTV) of unilateral breast cancer patients immobilized on Breast and Lung board of All-in-One (AIO) positioning systemmay necessitate augmented movement of couch in ‘x’ and ‘z’ axis thereby raising the risk of collusion of x-ray sources / detectors system with couch. Methods and Materials: VMAT was planned by a pair of partial arc for whole target volume for seven consecutive post-operative breast cancer patients (five post-mastectomy and two post-breast conservation patients). Tattoo based set-up by shift of treatment table in x-, y- and z-axis as determined by Treatment Planning System followed by X-rays with planar image acquisition and online 2-D imaging matching was performed for set-up verification. In-room 360°rotation of x-ray source and detector system of linear accelerator (linac) was performed before x-ray planar image acquisition. Results: Completion of 360°rotation in-room of x-ray source and detector system of linacaround the machine iso-centre was not possible in six out of seven patients due to possibility of collusion of gantry with contralateral side of the couch. Conclusion: Performing CBCT for generating 3D images for computed tomography (CT) reconstruction may not be practical for patient set-up verification of post-operative radiotherapy of unilateral breast cancer patients positioned supine on breast and lung board.

Mechanochemical Synthesis of Magnesium Doped Hydroxyapatite: Powder Characterization

2013 ◽  
Vol 372 ◽  
pp. 62-65 ◽  
Author(s):  
Sharifah Adzila ◽  
Singh Ramesh ◽  
Iis Sopyan ◽  
C.Y. Tan ◽  
Mohd. Hamdi ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Present Method ◽  
X Ray Diffraction ◽  
Mechanochemical Method ◽  
Xrd Pattern ◽  
X Ray ◽  
Hydroxyapatite Powder ◽  
Powder Properties ◽  
Mg Doped

In this study, the mechanochemical method was employed to synthesize hydroxyapatite (HA) and magnesium (Mg) doped hydroxyapatite (HA) powders. The effect of Mg2+ into the synthesized HA powder properties were investigated. Characterization of the synthesized HA and Mg doped HA at various concentrations (1% - 5% MgHA) were accomplished through X-ray diffraction (XRD) and Fourier transform infrared (FTIR) analyses. nanosize of HA and Mg doped HA powders were successfully synthesized through the present method as indicated from the different peaks intensity and adsorption bands obtained in XRD pattern and FTIR respectively.

Preparation and Characterization of Clays from Different Areas in Ban Bo Suak, Nan Province, Thailand

2015 ◽  
Vol 659 ◽  
pp. 127-131
Author(s):  
Usanee Malee ◽  
Sakdiphon Thiansem
Keyword(s):  
Clay Sample ◽  
X Ray Diffraction ◽  
Scientific Process ◽  
Quartz Content ◽  
Xrd Pattern ◽  
X Ray ◽  
Kiln Site ◽  
Before And After ◽  
Tone Color

The scientific process was used to explain characterization and physical properties of the clay sample close to the ancient Nan kiln site. These samples were obtained from JQA, FQB, PQC and NQD. X-ray diffraction (XRD) and X-ray fluorescence (XRF) technique were used to determine the chemical composition and phase transformation before and after fired at 800-1250 °C. XRF result was confirmed that all clay samples mainly contained SiO2(>80 wt. %) XRD pattern indicated that quartz was the majority of phase in the all of them. High amount of Fe2O3(>1.6 wt. %) was related to the red-brown tone color. The clay sample could be fired up to 1280 °C without wrapping behavior; it was found that FQB clay had the highest firing resistance due to the maximum quartz content.

Abstract LB-325: Characterization of triple negative breast cancer patients among Hispanics in Puerto Rico

2012 ◽  
Author(s):  
Edna M. Mora ◽  
Erick Suarez ◽  
Orquidea Frias ◽  
Carmen Gonzalez-Keelan ◽  
David Capo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Puerto Rico ◽  
Cancer Patients ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Breast Cancer Patients
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