Multiple Baseline Single-Case Experimental Design Using Statistical Analysis: Piloting a Mindfulness-Based Intervention for Obsessive–Compulsive Disorder

2018 ◽  
Author(s):  
Megan Wilkinson-Tough
Keyword(s):  
Statistical Analysis ◽  
Experimental Design ◽  
Obsessive Compulsive Disorder ◽  
Single Case ◽  
Multiple Baseline ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Treatment of Obsessive Compulsive Disorder and Excessive Reassurance Seeking in an Older Adult: A Single Case Quasi-Experimental Design

2017 ◽  
Vol 45 (6) ◽  
pp. 616-628 ◽  
Author(s):  
Brynjar Halldorsson ◽  
Paul M. Salkovskis
Keyword(s):  
Experimental Design ◽  
Obsessive Compulsive Disorder ◽  
Older Adult ◽  
Single Case ◽  
Obsessive Compulsive ◽  
Reassurance Seeking ◽  
Compulsive Disorder ◽  
Cognitive Behavioural ◽  
Excessive Reassurance Seeking ◽  
Quasi Experimental

Background: Cognitive behavioural interventions for excessive reassurance seeking (ERS) typically focus on encouraging individuals to refrain from seeking any reassurance and in some cases banning caregivers (e.g. family members) from providing it. However, this blanket consideration that reassurance is a bad thing that should simply be stopped may not always be appropriate or helpful. Cognitive behavioural treatment (CBT) targeting ERS by helping the sufferer to shift from seeking reassurance to seeking support may be a promising treatment intervention. Aims: This study aims to examine the targeted treatment of ERS in an older adult who has been suffering from severe obsessive compulsive disorder (OCD) for seven decades. Method: Using a single case quasi-experimental design (ABCD), the frequency of reassurance seeking, urges to seek reassurance, OCD beliefs and anxiety were measured daily for almost a year in addition to standard symptom measures. Results: At the end of treatment, visual inspection showed that reassurance seeking was no longer considered excessive and OCD severity fell from the severe to non-clinical range across the treatment sessions. All treatment gains were maintained at follow-up. Conclusions: This study illustrates how CBT can be successfully applied to treat long-standing OCD and ERS in an older adult. Engendering support as an alternative to reassurance seeking in CBT may be a particularly promising intervention for ERS.

COGNITIVE-BEHAVIOURAL TREATMENT OF A 14-YEAR-OLD TEENAGER WITH OBSESSIVE-COMPULSIVE DISORDER

2001 ◽  
Vol 29 (1) ◽  
pp. 71-84 ◽  
Author(s):  
Mark H. Freestone
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Single Case ◽  
Behavioural Intervention ◽  
Single Case Design ◽  
Unified Framework ◽  
Obsessive Compulsive ◽  
Behavioural Treatment ◽  
Compulsive Disorder ◽  
Cognitive Behavioural ◽  
Almost All

This study describes the treatment of severe obsessive-compulsive disorder in a 14-year-old male with an experimental single case design. Onset of OCD was at age 12. He had been hospitalized for 6 months the year before consulting. Almost all life spheres were affected by OCD. An initial behavioural intervention, which targeted tooth brushing, was used as a springboard to understand OCD and the process of change was framed within a cognitive account of OCD. The approach was then applied to a number of different targets within a unified framework. There was a 46% reduction in Y-BOCS score at post-treatment and 67% reduction through to 11-month follow-up. Points discussed include the involvement of other professionals, the changing role of the family as treatment progressed and as the patient started to seek more autonomy, and the choice of the initial target.

Bilateral Orbitomedial Leucotomy for Obsessive–Compulsive Disorder: A Single-Case Study Using Positron Emission Tomography

2001 ◽  
Vol 35 (5) ◽  
pp. 684-690 ◽  
Author(s):  
Perminder Sachdev ◽  
Julian Trollor ◽  
Alexandra Walker ◽  
Wei Wen ◽  
Michael Fulham ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Obsessive Compulsive Disorder ◽  
Single Case ◽  
Anterior Cingulate ◽  
Emission Tomography ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Caudate Head ◽  
Positron Emission ◽  
Medial Cortex

Objective: The objective of this report is to correlate the clinical outcome of neurosurgery for obsessive–compulsive disorder (OCD) with regional cerebral glucose metabolic changes. Clinical picture: The patient was a 37-year-old female patient with severe and intractable OCD. Treatment: The patient was treated with bilateral stereotactic lesions in the frontal white matter superior to the orbito-medial cortex. Outcome: She had a remarkable improvement in her obsessive–compulsive symptoms, which was sustained up to 3 years of follow up. A positron emission tomography (PET) scan performed 18 days after surgery demonstrated an obvious reduction of metabolism in the caudate head, anterior cingulate and orbital, medial and lateral prefrontal cortices and the thalamus. At 1 year postsurgery, metabolic rate was still reduced in the anterior cingulate gyrus, caudate and thalamus compared with preoperative baseline. The patient demonstrated no long-term cognitive effects of the surgery. Conclusions: This case supports some of the cortical-subcortical circuit dysfunction models of OCD and argues for the further evaluation of neurosurgery for the treatment of a severe and intractable disorder.

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