Prevalence of hypothyroidism and thyroid autoimmunity in polycystic ovarian syndrome patients: A North Indian study

2019 ◽  
Vol 16 (2) ◽  
pp. 55 ◽  
Author(s):  
Deepak Khandelwal ◽  
Diksha Goyal ◽  
Pooja Relia ◽  
Angela Sehra ◽  
Deep Dutta ◽  
...  
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Thyroid Autoimmunity ◽  
Indian Study ◽  
Ovarian Syndrome

scholarly journals 2021 European Thyroid Association Guideline on Thyroid Disorders prior to and during Assisted Reproduction

2020 ◽  
Vol 9 (6) ◽  
pp. 281-295
Author(s):  
Kris Poppe ◽  
Peter Bisschop ◽  
Laura Fugazzola ◽  
Gesthimani Minziori ◽  
David Unuane ◽  
...  
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Embryo Quality ◽  
Thyroid Autoimmunity ◽  
Thyroid Disorders ◽  
Menstrual Disorders ◽  
Normal Thyroid Function ◽  
Increased Risk ◽  
Meta Analyses ◽  
Ovarian Syndrome ◽  
Serum Tsh

Severe thyroid dysfunction may lead to menstrual disorders and subfertility. Fertility problems may persist even after restoring normal thyroid function, and then an assisted reproductive technology (ART) may be a solution. Prior to an ART treatment, ovarian stimulation is performed, leading to high oestradiol levels, which may lead to hypothyroidism in women with thyroid autoimmunity (TAI), necessitating levothyroxine (LT4) supplements before pregnancy. Moreover, women with the polycystic ovarian syndrome and idiopathic subfertility have a higher prevalence of TAI. Women with hypothyroidism treated with LT4 prior to ART should have a serum TSH level <2.5 mIU/L. Subfertile women with hyperthyroidism planning an ART procedure should be informed of the increased risk of maternal and foetal complications, and euthyroidism should be restored and maintained for several months prior to an ART treatment. Fertilisation rates and embryo quality may be impaired in women with TSH >4.0 mIU/L and improved with LT4 therapy. In meta-analyses that mainly included women with TSH levels >4.0 mIU/L, LT4 treatment increased live birth rates, but that was not the case in 2 recent interventional studies in euthyroid women with TAI. The importance of the increased use of intracytoplasmic sperm injection as a type of ART on pregnancy outcomes in women with TAI deserves more investigation. For all of the above reasons, women of subfertile couples should be screened routinely for the presence of thyroid disorders.

scholarly journals Polycystic ovarian syndrome and insulin resistance: a North Indian study

2015 ◽  
pp. 1321-1324 ◽  
Author(s):  
Nitin Agarwal ◽  
Sukanya Gangopadhyay ◽  
Nirensingh Koch ◽  
Akash Gupta ◽  
Aruna Batra ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Polycystic Ovarian Syndrome ◽  
Indian Study ◽  
Ovarian Syndrome

Association of VDBP and CYP2R1 gene polymorphisms with vitamin D status in women with polycystic ovarian syndrome: a north Indian study

2016 ◽  
Vol 57 (2) ◽  
pp. 703-711 ◽  
Author(s):  
Deepa Haldar ◽  
Nitin Agrawal ◽  
Seema Patel ◽  
Pankaj Ramrao Kambale ◽  
Kanchan Arora ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gene Polymorphisms ◽  
Polycystic Ovarian Syndrome ◽  
Vitamin D Status ◽  
Indian Study ◽  
Ovarian Syndrome

Characteristics of Polycystic Ovarian Syndrome in Sub-fertile Woman Attending to GOPD in ShSMCH

2019 ◽  
Vol 11 (1) ◽  
pp. 17-23
Author(s):  
Jinnat Ara Islam ◽  
Fatema Ashraf ◽  
Eva Rani Nandi
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovaries ◽  
Cross Sectional ◽  
Medical College ◽  
Appropriate Treatment ◽  
Pcos Group ◽  
Symptom Complex ◽  
Ovarian Syndrome ◽  
Selection Of ◽  
Fertile Women

Background: Polycystic ovarian syndrome (PCOS) is a condition characterized by menstrual abnormalities (oligo/amenorrhea) and clinical or biochemical features of hyperandrogenism and may manifest at any age. It is a common cause of female subfertility. All the dimensions of PCOS have not been yet completely explored. Methods: It was a cross sectional comparative study carried out at-GOPD of Shaheed Suhrawardy Medical College & Hospital from January, 2016 to December 2016 on 162 subfertile women. Among them 54 were PCOS group and 108 were non PCOS group. PCOS was diagnosed by (Rotterdam criteria 2003) (i) Oligo or anovulation (ii) hyperandrogenism (iii) Polycystic ovaries. Study was done to evaluate and compare the demographic characteristics, clinical, biochemical and ultrasoundgraphic features of sub-fertile women with and without PCOS. Results: A total of 162 sub-fertile women aged 16-36 years. Mean age was 29.5±5.4. There were significant differences between the two groups in terms of (oligo/amenorrhea), hirsutism, WHR and ovarian ultrasound features. There were no significant differences between two groups in correlations between the level of obesity with the incidence of anovulation, hyperandrogenism or with hormonal features. Conclusion: PCOS is one of the important factors causing Infertility. It is an ill-defined symptom complex needed due attention. There is a need to increase awareness regarding. The clinical features of PCOS are heterogenous thus can be investigated accordingly of selection of appropriate treatment modality. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 17-23

Impaired DHEA sulfation defines androgen excess in women with polycystic ovarian syndrome (PCOS)

2016 ◽  
Author(s):  
Punith Kempegowda ◽  
Michael W O'Reilly ◽  
Zaki Hassan-Smith ◽  
Karl-Heinz Storbeck ◽  
Angela E Taylor ◽  
...  
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Androgen Excess ◽  
Ovarian Syndrome

Visceral fat drives 5[alpha]-reductase activity independent of BMI in women with polycystic ovarian syndrome

2015 ◽  
Author(s):  
Punith Kempegowda ◽  
Michael W O'Reilly ◽  
Nicola J Crabtree ◽  
Angela E Taylor ◽  
Beverly A Hughes ◽  
...  
Keyword(s):  
Visceral Fat ◽  
Polycystic Ovarian Syndrome ◽  
Reductase Activity ◽  
Ovarian Syndrome
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