scholarly journals Correlation between thorax computed tomography findings and clinical and laboratory data on patients with coronavirus disease 2019

2021 ◽  
Vol 8 (1) ◽  
pp. 9
Author(s):  
Ruken Ergenc ◽  
DenizGizem Okray ◽  
Uygar Mutlu ◽  
Ahmet Tanyeri ◽  
MerveNizam Şahin
Keyword(s):  
Computed Tomography ◽  
Laboratory Data

The Prevalence of Nephrolithiasis in Patients with Primary Gout: A Cross-sectional Study Using Helical Computed Tomography

2009 ◽  
Vol 36 (9) ◽  
pp. 1958-1962 ◽  
Author(s):  
TORU SHIMIZU ◽  
HIROSHI HORI
Keyword(s):  
Computed Tomography ◽  
Confidence Interval ◽  
Laboratory Data ◽  
Helical Computed Tomography ◽  
Cross Sectional ◽  
Patients Âgés ◽  
Primary Gout ◽  
Stone Formers ◽  
Significant Difference ◽  
History Of

Objective.To investigate the prevalence of nephrolithiasis in gouty patients by computed tomography (CT) imaging and to compare it with the “prevalence” of urolithiasis calculated from histories of urinary tract calculus.Methods.The kidneys of 383 male patients with primary gout were examined using an unenhanced 2-row helical CT detector, imaging at 2 mm collimation and a helical pitch of 3. The urolithiasis history of the 383 patients was investigated by inquiry. Patients’ ages, body mass index, and laboratory data from a 1-hour clearance test were determined.Results.CT scans confirmed nephrolithiasis in 103 (26.9%, 95% confidence interval 22.5%–31.6%) of the 383 gouty patients, and history of urinary calculus was positive in 65 (17.0%, 95% confidence interval 13.4%–21.1%) of the 383. However, 64 (62%) of the 103 stone-formers identified by CT had no history of urolithiasis. There was a significant difference between the ages of the 103 stone-formers identified by CT and the 65 stone-formers identified from the history.Conclusion.The prevalence of nephrolithiasis obtained using CT was 26.9% in the 383 patients with primary gout. Our results imply that we cannot determine an accurate prevalence of urolithiasis from a patient’s history. Most of the “prevalence” reported in the past may not correspond to a statistically justifiable one, but instead to the “cumulative incidence” during the contraction period of gout. Thus, the prevalence of nephrolithiasis confirmed by a cross-sectional method and the “prevalence” of urolithiasis calculated from patients’ calculus histories should be clearly distinguished.

scholarly journals Computed tomography semi-automated lung volume quantification in SARS-CoV-2-related pneumonia

2020 ◽  
Author(s):  
Davide Ippolito ◽  
Maria Ragusi ◽  
Davide Gandola ◽  
Cesare Maino ◽  
Anna Pecorelli ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Volume ◽  
Laboratory Data ◽  
Ground Glass Opacity ◽  
Invasive Ventilation ◽  
Lung Volumes ◽  
Total Lung Volume ◽  
Reactive Protein ◽  
Absolute Volume ◽  
Patient’S Outcome

Abstract Objectives To evaluate a semi-automated segmentation and ventilated lung quantification on chest computed tomography (CT) to assess lung involvement in patients affected by SARS-CoV-2. Results were compared with clinical and functional parameters and outcomes. Methods All images underwent quantitative analyses with a dedicated workstation using a semi-automatic lung segmentation software to compute ventilated lung volume (VLV), Ground-glass opacity (GGO) volume (GGO-V), and consolidation volume (CONS-V) as absolute volume and as a percentage of total lung volume (TLV). The ratio between CONS-V, GGO-V, and VLV (CONS-V/VLV and GGO-V/VLV, respectively), TLV (CONS-V/TLV, GGO-V/TLV, and GGO-V + CONS-V/TLV respectively), and the ratio between VLV and TLV (VLV/TLV) were calculated. Results A total of 108 patients were enrolled. GGO-V/TLV significantly correlated with WBC (r = 0.369), neutrophils (r = 0.446), platelets (r = 0.182), CRP (r = 0.190), PaCO2 (r = 0.176), HCO3− (r = 0.284), and PaO2/FiO2 (P/F) values (r = − 0.344). CONS-V/TLV significantly correlated with WBC (r = 0.294), neutrophils (r = 0.300), lymphocytes (r = −0.225), CRP (r = 0.306), PaCO2 (r = 0.227), pH (r = 0.162), HCO3− (r = 0.394), and P/F (r = − 0.419) values. Statistically significant differences between CONS-V, GGO-V, GGO-V/TLV, CONS-V/TLV, GGO-V/VLV, CONS-V/VLV, GGO-V + CONS-V/TLV, VLV/TLV, CT score, and invasive ventilation by ET were found (all p < 0.05). Conclusion The use of quantitative semi-automated algorithm for lung CT elaboration effectively correlates the severity of SARS-CoV-2-related pneumonia with laboratory parameters and the need for invasive ventilation. Key Points • Pathological lung volumes, expressed both as GGO-V and as CONS-V, can be considered a useful tool in SARS-CoV-2-related pneumonia. • All lung volumes, expressed themselves and as ratio with TLV and VLV, correlate with laboratory data, in particular C-reactive protein and white blood cell count. • All lung volumes correlate with patient’s outcome, in particular concerning invasive ventilation.

scholarly journals Clinical Utility of Functional Imaging with 18F-FDOPA in Von Hippel-Lindau Syndrome

2012 ◽  
Vol 97 (4) ◽  
pp. E613-E617 ◽  
Author(s):  
Allison B. Weisbrod ◽  
Mio Kitano ◽  
Krisana Gesuwan ◽  
Corina Millo ◽  
Peter Herscovitch ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Neuroendocrine Tumors ◽  
Clinical Utility ◽  
Laboratory Data ◽  
Imaging Modalities ◽  
Metabolic Imaging ◽  
High Risk Population ◽  
Von Hippel Lindau ◽  
18F Fluorodeoxyglucose ◽  
Fluorodeoxyglucose Pet

Context: Von Hippel-Lindau (VHL) syndrome is an inherited cancer syndrome in which patients are at risk of developing multiple tumors in different organs. 6-L-18F-fluorodihydroxyphenylalanine (18F-FDOPA) positron emission tomography (PET) is a relatively new metabolic imaging tracer proposed for the use of localizing sites of neuroendocrine tumors. There are limited data on the clinical utility of using 18F-FDOPA PET for identifying neuroendocrine tumors in a high-risk population such as VHL. Objective: The aim of this prospective study was to evaluate the clinical utility of 18F-FDOPA PET in patients with VHL-related tumors. Design: Radiological findings were prospectively collected from four imaging modalities: computed tomography, magnetic resonance imaging (MRI), 18F-fluorodeoxyglucose PET, and 18F-FDOPA PET. 18F-FDOPA PET findings were compared with those from other imaging modalities, as well as with clinical and laboratory data, and pathology findings if patients underwent an operation. Results: In 52 patients with VHL, 390 lesions were identified by computed tomography (n = 139), MRI (n = 117), 18F-fluorodeoxyglucose PET (n = 94), and 18F-FDOPA PET (n = 40). 18F-FDOPA PET identified 20 pancreatic and 20 extrapancreatic tumors, including lesions in the adrenal gland (n = 11), kidney (n = 3), liver (n = 4), lung (n = 1), and cervical paraganglioma (n = 1). These tumor sites were not seen by conventional imaging studies in 9.6% of patients and 4.4% of lesions. Seven of eight patients who had an 18F-FDOPA PET-positive lesion underwent resection, and pathology showed a neuroendocrine tumor. Four of 10 patients with positive adrenal uptake had elevated catecholamine levels, and six of 10 patients had a discrete mass on axial imaging. Conclusions: 18F-FDOPA PET is a useful complementary imaging study to detect neuroendocrine tumors in patients with VHL undergoing surveillance, especially in those suspected to have adrenal pheochromocytoma or unusual ectopic locations.

scholarly journals Imaging of Cardiac Device-Related Infection

2021 ◽  
Vol 8 ◽  
Author(s):  
Jose Aguilera ◽  
Erika Hutt ◽  
Wael A. Jaber
Keyword(s):  
Computed Tomography ◽  
Tissue Characterization ◽  
Multimodality Imaging ◽  
Financial Burden ◽  
Laboratory Data ◽  
Diagnostic Tools ◽  
Prosthetic Material ◽  
International Consensus ◽  
Cardiac Device ◽  
Cardiac Devices

Cardiac devices are frequently used in different cardiovascular conditions for the purpose of morbidity or mortality prevention. These include cardiac implantable electronic devices (CIED) like permanent pacemakers and implantable cardiac defibrillators, ventricular assistance devices (VADs), left atrial appendage occlusion (LAAO) devices like the Watchman™, atrial and ventricular septal occluders like the Amplatzer™, among others. In the past years, there has been an increase in the development of these devices as a result of a rise in the number of indications for implantation, paired with the aging and more medically complex patient population. This has led to an increase in the incidence of cardiac device-related infections, one of the most feared and serious complications which is associated with significant morbidity, mortality and financial burden. Accurate diagnosis of cardiac device-related infections is essential given the management implications which often involve removal of the infected device, removal of other prosthetic material and long-term antimicrobial therapy. Clinical and laboratory data are useful diagnostic tools but multimodality imaging is often necessary. The recently published 2020 European Heart Rhythm Association International Consensus document, which is endorsed by many expert societies, has recommended the use of multimodality imaging for the diagnosis of CIED infections. (1) This allows better disease characterization by identifying abnormal fluid collections and guiding aspiration for both diagnostic and therapeutic purposes (i.e. soft tissue ultrasound and computed tomography), evaluation for local extent of disease (i.e. transesophageal echocardiogram to evaluate for concomitant infective endocarditis), embolic manifestation of disease (i.e. computed tomography and magnetic resonance imaging) and metabolic tissue characterization (positron emission tomography and tagged white blood cell scan). (2) In addition, computed tomography (CT) allows for pre-procedural planning which has shown to be associated with better procedural outcomes.

scholarly journals The Value of Big Endothelin-1 in the Assessment of the Severity of Coronary Artery Calcification

2018 ◽  
Vol 24 (7) ◽  
pp. 1042-1049 ◽  
Author(s):  
Fang Wang ◽  
Tiewei Li ◽  
Xiangfeng Cong ◽  
Zhihui Hou ◽  
Bin Lu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Artery ◽  
Coronary Artery Calcification ◽  
Laboratory Data ◽  
Calcium Score ◽  
Enzyme Linked Immunosorbent Assay ◽  
Roc Curve Analysis ◽  
Preliminary Screening ◽  
Endothelin 1 ◽  
All Cause Mortality

Progression of coronary artery calcification (CAC) was significantly associated with all-cause mortality, and high coronary artery calcium score (CACS) portends a particularly high risk of cardiovascular events. But how often one should rescan is still an unanswered question. Preliminary screening by testing circulating biomarker may be an alternative before repeat computed tomography (CT) scan. The aim of this study was to investigate the value of big endothelin-1 (bigET-1), the precursor of endothelin-1 (ET-1), in predicting the severity of CAC. A total of 428 consecutively patients who performed coronary computed tomography angiography (CCTA) due to chest pain in Fuwai Hospital were included in the study. The clinical characteristics, CACS, and laboratory data were collected, and plasma bigET-1 was detected by enzyme-linked immunosorbent assay (ELISA). The bigET-1 was positively correlated with the CACS ( r = .232, P < .001), and the prevalence of CACS >400 increased significantly in the highest bigET-1 tertile than the lowest tertile. Multivariate analysis showed that bigET-1was the independent predictor of the presence of CACS >400 (odds ratio [OR] = 1.721, 95% confidence interval [CI], 1.002-2.956, P = .049). The receiver operating characteristic (ROC) curve analysis showed that the optimal cutoff value of bigET-1 for predicting CACS >400 was 0.38 pmol/L, with a sensitivity of 59% and specificity of 68% (area under curve [AUC] = 0.65, 95% CI, 0.58-0.72, P < .001). The present study demonstrated that the circulating bigET-1 was valuable in the assessment of the severity of CAC.

scholarly journals A Case of Urinary Sepsis Secondary to Streptococcus sanguinis

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Ashley Reuter ◽  
Ashley Heyman ◽  
Benjamin Stockton ◽  
David Kraklau ◽  
Michael S. Wang
Keyword(s):  
Computed Tomography ◽  
Ureteral Stone ◽  
Laboratory Data ◽  
Complete Recovery ◽  
Blood Cultures ◽  
Flank Pain ◽  
Transesophageal Echocardiogram ◽  
Streptococcus Sanguinis ◽  
History Of ◽  
Urinary Sepsis

We report a case of a 71-year-old male with a history of BPH who presented with flank pain, fever, chills, abdominal pain, and nausea. He had a dental cleaning 1 month prior to admission and flosses daily. Laboratory data revealed both urine and blood cultures to be positive for streptococcus sanguinis. Computed tomography revealed a 10 mm right ureteral stone, and an ultrasound demonstrated moderate right hydronephrosis. He underwent an ureteroscopy with stent placement. A transesophageal echocardiogram was negative for endocarditis. He completed 2 weeks of IV ceftriaxone and made a complete recovery.

scholarly journals Characterization of the Carbonate Formation Fracture System Based on Well Logging Data and Results of Laboratory Measurements

Energies ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 6034
Author(s):  
Marek Stadtműller ◽  
Paulina I. Krakowska-Madejska ◽  
Grzegorz Leśniak ◽  
Jadwiga A. Jarzyna
Keyword(s):  
Computed Tomography ◽  
Carbonate Rock ◽  
Laboratory Data ◽  
Well Logging ◽  
Polished Section ◽  
Fracture System ◽  
Micro Computed Tomography ◽  
Carbonate Formation ◽  
Porosity And Permeability ◽  
Dolomite Formation

This article presents a novel methodology for data integration including laboratory data, the results of standard well logging measurements and interpretation and the interpretation of XRMI imager data for determination of the porosity and permeability of the fracture system in carbonate rock. An example of the results of the micro computed tomography applied for carbonate rock is included. Data were obtained on the area of the Polish Lowland Zechstein Main Dolomite formation. The input set of data included the results of mercury injection porosimetry (MICP), thin section and polished section analysis, well logging measurements and comprehensive interpretation and micro computed tomography. The methodology of the macrofractures’ analysis based on borehole wall imagery as well as estimation of their aperture was described in detail. The petrophysical characteristics of the fracture systems were analyzed as an element of standard interpretation of well logging data along a carbonate formation. The results of permeability determination, with micro-, mezzo- and macrofractures’ presence in the rock taken into consideration, were compared with outcomes of the drill stem tests (DSTs).

scholarly journals Medical Imaging in the Diagnosis of Schistosomiasis: A Review

Pathogens ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1058
Author(s):  
Andrea Cimini ◽  
Maria Ricci ◽  
Paola Elda Gigliotti ◽  
Luca Pugliese ◽  
Agostino Chiaravalloti ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Diagnostic Imaging ◽  
Imaging Techniques ◽  
Laboratory Data ◽  
Daily Practice ◽  
Imaging Features ◽  
X Rays ◽  
Positron Emission ◽  
Diagnostic Imaging Techniques ◽  
Magnetic Resonance Imaging Mri

Schistosomiasis is one of the most important parasitic diseases and it is endemic in tropical and subtropical areas. Clinical and laboratory data are fundamental for the diagnosis of schistosomiasis, but diagnostic imaging techniques such as x-rays, ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT) may be helpful in the evaluation of disease severity and complications. In this context, the aim of this review is to explore the actual role of diagnostic imaging in the diagnosis of schistosomiasis, underlining advantages and drawbacks providing information about the utilization of diagnostic imaging techniques in this context. Furthermore, we aim to provide a useful guide regarding imaging features of schistosomiasis for radiology and nuclear medicine physicians of non-endemic countries: in fact, in the last years non-endemic countries have experienced important flows of migrants from endemic areas, therefore it is not uncommon to face cases of this disease in daily practice.

scholarly journals TAP-Stenting Technique for Bifurcation Stenosis of Celiac Artery

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Yucel Colkesen ◽  
Taner Seker ◽  
Osman Kuloglu ◽  
Murat Çayli
Keyword(s):  
Computed Tomography ◽  
Abdominal Pain ◽  
Liver Injury ◽  
Clinical Course ◽  
Laboratory Data ◽  
Exploratory Laparotomy ◽  
Celiac Artery ◽  
Hepatic Enzymes ◽  
Total Occlusion ◽  
Endovascular Recanalization

We report a clinical course of a patient who developed severe ischemic liver injury and total occlusion of the celiac artery (CA). A 40-year-old man presented with abdominal pain. Computed tomography indicated total occlusion of the CA. Laboratory data demonstrated markedly elevated hepatic enzymes. An exploratory laparotomy was not necessitated due to absence of peritonism. The patient was successfully treated by endovascular recanalization of the CA occlusion via transcatheter balloon angioplasty and TAP-stenting (T-stenting and small protrusion) technique. Endovascular intervention in patients solely with liver failure appears practicable and early treatment is advised.

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