scholarly journals Tyrosinase inhibitory activities of Carissa opaca Stapf ex haines roots extracts and their phytochemical analysis

2017 ◽  
Vol 13 (51) ◽  
pp. 544 ◽  
Author(s):  
Dildar Ahmed ◽  
Wajeeha Malik ◽  
Sania Izhar
2010 ◽  
Vol 131 (1) ◽  
pp. 22-27 ◽  
Author(s):  
A.O. Aremu ◽  
O.A. Fawole ◽  
J.C. Chukwujekwu ◽  
M.E. Light ◽  
J.F. Finnie ◽  
...  

2019 ◽  
Vol 141 ◽  
pp. 111771 ◽  
Author(s):  
Yongsheng Chen ◽  
Erpei Wang ◽  
Zihao Wei ◽  
Yanfang Zheng ◽  
Rian Yan ◽  
...  

2020 ◽  
Vol 11 ◽  
Author(s):  
Minyi Tian ◽  
Xianghuan Wu ◽  
Tingya Lu ◽  
Xiaoge Zhao ◽  
Feng Wei ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Arif Nisha Syad ◽  
Karutha Pandian Shunmugiah ◽  
Pandima Devi Kasi

The effect of various solvent extracts ofGelidiella acerosaon acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities was investigated. AChE and BuChE inhibitory activities were analyzed by spectrophotometric method. Phytochemical screening of the compounds present in the solvent extracts was done qualitatively. Characterization of the compounds present in the benzene extract ofG. acerosawas done by GC-MS analysis. The results showed that, at 487.80 μg/mL, benzene extract showed significant (P<0.05) inhibitory activity against both AChE and BuChE with the percentage of inhibition54.18±5.65% (IC50 = 434.61±26.53 μg/mL) and78.43±0% (IC50 = 163.01±85.35 μg/mL), respectively. The mode of inhibition exhibited by benzene extract against the AChE and BuChE was found to be competitive and uncompetitive type of inhibition, respectively. Preliminary phytochemical analysis coupled with GC-MS illustrates that the benzene extract possesses high amount of terpenoids, which could be the reason for potential cholinesterase inhibitory activity.


2021 ◽  
Vol 34 (1) ◽  
pp. 55-59
Author(s):  
Karolina Wojtunik-Kulesza ◽  
Kamila Kasprzak-Drozd ◽  
Daniel Sajdlowski ◽  
Anna Oniszczuk ◽  
Wojciech Swiatkowski ◽  
...  

Abstract Scutellaria baicalensis, known also as Huang-Qin is a traditional Chinese plant used in medicine for at least 2000 years. The plant is widely distributed in Japan, Korea, Mongolia and Russia, and is listed in Chinese Pharmacopoeia, European Pharmacopoeia and British Pharmacopoeia. The interest in Huang-Qin results from various biological activities which are primarily related to secondary plants metabolites consisting of flavonoids, phenolic compounds and terpenes. It is known that the compounds are active against numerous diseases and protect the organism against harmful pathogenic agents. Particular attention is paid to baicalein, wogonin and oroxylin A – which are characteristic secondary metabolites of the plant. In this paper, we focused on phytochemical analysis and selected biological activities used in periodontal and cardiovascular problems. The presented studies confirm the ability of Huang-Qin to scavenge free radicals, moreover, that it presents anti-bacterial, anti-inflammatory and enzyme inhibitory activities.


2022 ◽  
Author(s):  
Laurent Voufack Lefack Bongmo ◽  
Gervais Mouthé Happi ◽  
George Bellier Tabekoueng ◽  
Mehreen Lateef ◽  
Alain François Kamdem Waffo ◽  
...  

Thirteen compounds (<b>1</b>‒<b>13</b>) were isolated and identified during phytochemical analysis of the leaves and stem bark of <i>Guibourtia ehie</i> (A. Chev) J. Leonard. Spectroscopic and spectrometric methods and the comparison of their results with those given in the literature were used to ascertain their structures. Furthermore, the acetylation of 3,3′-di-<i>O</i>-methylellagic acid 4′-<i>O</i>-β-D-xylopyranoside (<b>2</b>) afforded a new derivative 3,3′-di-<i>O</i>-methylellagic acid 4′-<i>O</i>-β-D-(4,2′′,4′′-triacetyl)-xylopyranoside (<b>2a</b>). Extracts, fractions, and isolated compounds were assessed for their antioxidant, urease, and α-glucosidase inhibitory activities. Compound <b>1</b> demonstrated potent antioxidant activity in the DPPH with an IC<sub>50</sub> value of 36.4 ± 0.2 µM, while rhaponticin (<b>3</b>), 2,6-dimethoxybenzoquinone (<b>4</b>), and taraxerol (<b>6</b>) exhibited a strong α-glucosidase inhibitory activity with the IC<sub>50</sub> values of 35.5 ± 0.1, 25.5 ± 0.2 and 43.4 ± 0.3 µM, respectively. The present study enriches the chemistry of <i>Guiboutia ehie</i> and provides further evidence on its bioactive constituents, which might help in the development of hypoglycaemic drugs.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
SK Tsermentseli ◽  
AN Assimopoulou ◽  
N Gianovits-Argyriadou ◽  
FI Kanaze ◽  
VP Papageorgiou

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