Normalization of insulin resistance, glucose intolerance, and lipid profile by Swietenia Mahagoni (L.) Jacq. leaf extract in fructose-induced diabetic rats

2018 ◽  
Vol 14 (59) ◽  
pp. 649
Author(s):  
Asna Urooj ◽  
NaveenY Puttaswamy
Keyword(s):  
Insulin Resistance ◽  
Lipid Profile ◽  
Glucose Intolerance ◽  
Leaf Extract ◽  
Diabetic Rats ◽  
Swietenia Mahagoni

scholarly journals Comparative Effects of Curcumin versus Nano-Curcumin on Insulin Resistance, Serum Levels of Apelin and Lipid Profile in Type 2 Diabetic Rats

2020 ◽  
Vol Volume 13 ◽  
pp. 2337-2346 ◽  
Author(s):  
Ali Shamsi-Goushki ◽  
Zinat Mortazavi ◽  
Mohammad Ali Mirshekar ◽  
Mahdi Mohammadi ◽  
Nasroallah Moradi-Kor ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Lipid Profile ◽  
Serum Levels ◽  
Diabetic Rats ◽  
Type 2 Diabetic

scholarly journals Lipid profile status of streptozotocin induced diabetic rats treated with ethanolic leaf extract of Solenostemon monostachyus

2015 ◽  
Vol 9 (8) ◽  
pp. 289-293 ◽  
Author(s):  
Amaechi Dennis ◽  
O. Udosen E. ◽  
E. Edet E. ◽  
E. Asanga E. ◽  
E. Mbakwe I.
Keyword(s):  
Lipid Profile ◽  
Leaf Extract ◽  
Diabetic Rats ◽  
Ethanolic Leaf Extract

Effect of Crocin on the Insulin Resistance and Lipid Profile of Streptozotocin‐Induced Diabetic Rats

2012 ◽  
Vol 27 (7) ◽  
pp. 1042-1047 ◽  
Author(s):  
Saeed Shirali ◽  
S. Zahra Bathaie ◽  
Manouchehr Nakhjavani
Keyword(s):  
Insulin Resistance ◽  
Lipid Profile ◽  
Diabetic Rats

scholarly journals GABA administration improves liver function and insulin resistance in offspring of type 2 diabetic rats

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Azadehalsadat Hosseini Dastgerdi ◽  
Mohammadreza Sharifi ◽  
Nepton Soltani
Keyword(s):  
Insulin Resistance ◽  
Lipid Profile ◽  
Liver Lipid ◽  
Liver Glycogen ◽  
Tolerance Test ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Insulin Tolerance ◽  
Liver Insulin Resistance

AbstractThis study investigated the role of GABA in attenuating liver insulin resistance (IR) in type 2 diabetes parents and reducing its risk in their descendants’ liver. Both sexes’ rats were divided into four groups of non-diabetic control, diabetic control (DC), GABA-treated (GABA), and insulin-treated (Ins). The study duration lasted for six months and the young animals followed for four months. Consequently, hyperinsulinemic-euglycemic clamp was performed for all animals. Apart from insulin tolerance test (ITT), serum and liver lipid profile were measured in all groups. Glycogen levels, expression of Foxo1, Irs2, Akt2, and Pepck genes in the liver were assessed for all groups. Overall, GABA improved ITT, increased liver glycogen levels and decreased lipid profile, blood glucose level, and HbA1c in parents and their offspring in compared to the DC group. GIR also increased in both parents and their offspring by GABA. Moreover, the expression of Foxo1, Irs2, Akt2, and Pepck genes improved in GABA-treated parents and their descendants in compared to DC group. Results indicated that GABA reduced liver IR in both parents and their offspring via affecting their liver insulin signaling and gluconeogenesis pathways.

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