Antioxidant and anticancer activities of whole plant extracts of Lepidagathis pungens nees: In vitro evaluation

2021 ◽  
Vol 17 (5) ◽  
pp. 63
Author(s):  
SubramaniamAnanda Thangadurai ◽  
Manoharan Dhanalakshmi
Keyword(s):  
Plant Extracts ◽  
Anticancer Activities ◽  
In Vitro Evaluation ◽  
Whole Plant

scholarly journals Synthesis and In vitro Evaluation of novel 5‐nitroIndole Derivatives as c‐Myc G‐Quadruplex Binders with Anticancer Activities

ChemMedChem ◽  
2021 ◽  
Author(s):  
Vijaykumar D. Nimbarte ◽  
Julia Wirmer-Bartoschek ◽  
Santosh L. Gande ◽  
Islam Alshamleh ◽  
Marcel Seibert ◽  
...  
Keyword(s):  
Anticancer Activities ◽  
In Vitro Evaluation ◽  
G Quadruplex

scholarly journals In vitro and In vivo Antidiabetic Evaluation of Whole Plant Extracts of Argyreia imbricata (Roth) Sant. and Patel

2021 ◽  
Vol 13 (1) ◽  
pp. 30-36
Author(s):  
Sebastin V Sebastin ◽  
Gopalakrishnan G Gopalakrishnan ◽  
Sreejith M Sreejith ◽  
KI Anoob Kumar
Keyword(s):  
Plant Extracts ◽  
Whole Plant

scholarly journals Biocidal Potential of Plants Extracts Against Wood-Degrading Microbes and Their In-Vitro Application on Wood: As Promising Wood Natural Preservatives

2021 ◽  
Author(s):  
Amina Ifthkar ◽  
Faiza Jabeen ◽  
Saima Mirza ◽  
Afshan Abbas ◽  
Tahira Younis ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Ethanol Extract ◽  
Wood Protection ◽  
Whole Plant ◽  
Increasing Demand ◽  
Decaying Wood ◽  
Natural Preservatives ◽  
Fungal Deterioration ◽  
Microbial Attack

Abstract Background: Besides the increasing demand of wooden articles, there is a burning issue of microbial attack which affects the aesthetics of wood. Thus it is a current concern to protect the wooden articles from both fungal and bacterial attack by using toxin free preservatives. Results: Powder of Calotropis procera (leaves), Curcuma zedoaria (rhizome) and Swertia chirata (whole plant) was extracted with solvents like methanol, ethanol and chloroform and then the qualitative phytochemical screening was carried out, which exhibited the presence of different secondary metabolites. These extracts were also evaluated against wood degrading microbes (Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Aspergillus flavus and Aspergillus niger) isolated from decaying wood. Our study demonstrated that the ethanol extract of S. chairata showed highest bactericidal potential against E.coli (19.0mm) and A. flavus (19.33mm). This study also revealed that S. chirata exhibited strongest biocidal spectrum of action followed by C. procera and C. zedaira. It was observed that laminated veneer treated with ethanol extract of S. chirata showed strong bactericidal potential against E.coli (82.67mm). On the other hand Syzygium cumini wood treated with ethanol extract of C. zedoaria exhibited high antibacterial potential against P. aeruginosa (58.0mm). The active plant extracts showed MIC's ranged from 3.6 to 6.0 mg/ml and MBC/MFC of 4.8 and 8.4 mg/ml. Conclusion: The results demonstrated the potential effects of selected plant extracts as a natural preservative that can protect wood from bacterial and fungal deterioration. The extracts can be applied to prevent furniture deterioration and raw wood protection.

scholarly journals Review of Whole Plant Extracts With Activity Against Herpes Simplex Viruses In Vitro and In Vivo

2021 ◽  
Vol 26 ◽  
pp. 2515690X2097839
Author(s):  
Anna Garber ◽  
Lianna Barnard ◽  
Chris Pickrell
Keyword(s):  
Herpes Simplex ◽  
Plant Extracts ◽  
Animal Cell ◽  
Model Design ◽  
Herpes Simplex Viruses ◽  
Whole Plant ◽  
Antiviral Medications ◽  
Hsv 1

Herpes simplex viruses, HSV-1 and HSV-2, are highly contagious and cause lifelong, latent infections with recurrent outbreaks of oral and/or genital lesions. No cure exists for HSV-1 or HSV-2 infections, but antiviral medications are commonly used to prevent and treat outbreaks. Resistance to antivirals has begun to emerge, placing an importance on finding new and effective therapies for prophylaxis and treatment of HSV outbreaks. Botanicals may be effective HSV therapies as the constituents they contain act through a variety of mechanisms, potentially making the development of antiviral resistance more challenging. A wide variety of plants from different regions in the world have been studied for antiviral activity against HSV-1 and/or HSV-2 and showed efficacy of varying degrees. The purpose of this review is to summarize research conducted on whole plant extracts against HSV-1 and/or HSV-2 in vitro and in vivo. The majority of the research reviewed was conducted in vitro using animal cell lines, and some studies used an animal model design. Also summarized are a limited number of human trials conducted using botanical therapies on HSV lesions.

scholarly journals In vitro screening of antioxidant, free radical scavenging and antimicrobial potential of Micrococca mercurialis whole plant extracts

2019 ◽  
Vol 10 (4) ◽  
pp. 3251-3262
Author(s):  
Thendral Hepsibha B ◽  
Gayathri Devi R ◽  
Lijitha L
Keyword(s):  
Free Radical ◽  
Plant Extracts ◽  
Skin Diseases ◽  
Biological Activities ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Whole Plant ◽  
Anti Inflammatory ◽  
Scientific Validation

Micrococca mercurialis is widely used for the treatment of sores, skin diseases, cold, fever, rheumatic pain, and infections. The present study aimed to study the antioxidant, free radical scavenging and antibacterial potential different whole plant extracts (aqueous, ethanol, petroleum ether) of Micrococca mercurialis by in vitro methods. The amount of phenols, tannins, flavonoids and Vitamin C were estimated by conventional methods. Free radical scavenging potential was assessed by DPPH and FRAP assays. HRBC membrane-stabilizing study was done to determine its anti-inflammatory property by in vitro method. Activity against Staphylococcus aureus and Bacillus subtilis were determined in Micrococca mercurialis extracts. The phytoconstituents in the extracts of Micrococca mercurialis were explored by GC-MS analysis. The extracts of Micrococca mercurialis exhibited varied in vitro antioxidant, free radical scavenging, antibacterial and anti-inflammatory activities. The GC–MS results confirmed the presence of twenty-nine phytoconstituents totally responsible for the biological activities of Micrococca mercurialis. This pilot study has provided a scientific validation for the folkloric use of Micrococca mercurialis against many infections and diseases.

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