Vasorelaxant effect of the ethanol extract from Valeriana fauriei briquet root and rhizome on rat thoracic aorta

2019 ◽  
Vol 15 (60) ◽  
pp. 59
Author(s):  
Ho-Young Choi ◽  
Bumjung Kim ◽  
Shin-Saeng Ma ◽  
Cheolmin Jo ◽  
Somin Lee ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Ethanol Extract ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta

scholarly journals UPLC-DAD/Q-TOF-MS Based Ingredients Identification and Vasorelaxant Effect of Ethanol Extract of Jasmine Flower

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yongqiang Yin ◽  
Xuhui Ying ◽  
Hairong Luan ◽  
Zhenying Zhao ◽  
Jianshi Lou ◽  
...  
Keyword(s):  
Laser Scanning ◽  
Iridoid Glycosides ◽  
Ethanol Extract ◽  
Flavonoid Glycosides ◽  
Free Medium ◽  
Vasorelaxant Effect ◽  
Medicinal Value ◽  
Jasmine Tea ◽  
Rat Thoracic Aorta ◽  
Tof Ms

Chinese people commonly make jasmine tea for recreation and health care. Actually, its medicinal value needs more exploration. In this study, vasorelaxant effect of ethanol extract of jasmine flower (EEJ) on isolated rat thoracic aorta rings was investigated and [Ca2+] was determined in vascular smooth muscle cells by laser scanning confocal microscope (LSCM). The result of aorta rings showed that EEJ could cause concentration-dependent relaxation of endothelium-intact rings precontracted with phenylephrine or KCl which was attenuated after preincubation of the rings with L-NAME and three different K+channel inhibitors; however, indomethacin and glibenclamide did not affect the vasodilatation of EEJ. In addition, EEJ could inhibit contraction induced by PE on endothelium-denuded rings in Ca2+-free medium as well as by accumulation of Ca2+in Ca2+-free medium with high K+. LSCM also showed that EEJ could lower the elevated level of [Ca2+] induced by KCl. These indicate that the vasodilation of EEJ is in part related to causing the release of nitric oxide, activation of K+channels, inhibition of influx of excalcium, and release of calcium from sarcoplasmic reticulum. A total of 20 main ingredients, were identified in EEJ by UPLC-DAD/Q-TOF-MS. The vasodilation activity should be attributed to the high content of flavonoid glycosides and iridoid glycosides found in EEJ.

Vasorelaxant effect of trans‐4‐chloro‐β‐nitrostyrene, a synthetic nitroderivative, in rat thoracic aorta

2020 ◽  
Author(s):  
Hellida Larissa Sousa‐Brito ◽  
Loeste Arruda‐Barbosa ◽  
Alfredo Augusto Vasconcelos‐Silva ◽  
Karoline Gonzaga‐Costa ◽  
Gloria Pinto Duarte ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta

Endothelium-independent vasorelaxant effect of sodium ferulate on rat thoracic aorta

Life Sciences ◽  
2009 ◽  
Vol 84 (3-4) ◽  
pp. 81-88 ◽  
Author(s):  
Guo-Ping Chen ◽  
Yang Ye ◽  
Liang Li ◽  
Yin Yang ◽  
An-Bin Qian ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Sodium Ferulate ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta

scholarly journals The vasorelaxant effect of Canarium odontophyllum Miq. (Dabai) extract in rat thoracic aorta

2018 ◽  
Vol 5 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Dayang Fredalina Basri ◽  
Nur Sa'adah Abdul Rahman ◽  
Shafreena Shaukat Ali ◽  
Satirah Zainalabidin
Keyword(s):  
Thoracic Aorta ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta ◽  
Canarium Odontophyllum

Vasorelaxant effect of euxanthone in the rat thoracic aorta

2006 ◽  
Vol 45 (2) ◽  
pp. 96-101 ◽  
Author(s):  
Lian-Hua Fang ◽  
Ya-Mei Mu ◽  
Li-Lin Lin ◽  
Pei-Gen Xiao ◽  
Guan-Hua Du
Keyword(s):  
Thoracic Aorta ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta

Vasorelaxant effect of formononetin in the rat thoracic aorta and its mechanisms

2012 ◽  
Vol 14 (1) ◽  
pp. 46-54 ◽  
Author(s):  
Yan Zhao ◽  
Bai-Nian Chen ◽  
Shou-Bao Wang ◽  
Shao-Hua Wang ◽  
Guan-Hua Du
Keyword(s):  
Thoracic Aorta ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta

scholarly journals VASORELAXANT EFFECT OF THE ALKALOID 1-0-BENZOYLNAPPELINE ON ISOLATED RAT THORACIC AORTA

2020 ◽  
Vol 05 (02) ◽  
pp. 146-156
Author(s):  
Adilbay Esimbetov ◽  
Abdisalim Zaripov ◽  
Sirojiddin Omonturdiev ◽  
Mukhlis Sultankhodjaev ◽  
Pulat Usmanov
Keyword(s):  
Thoracic Aorta ◽  
Vasorelaxant Effect ◽  
Rat Thoracic Aorta ◽  
Isolated Rat
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