scholarly journals Influence of smoking on gingival crevicular fluid interleukin 1β and interleukin-8 in patients with severe chronic periodontitis among a Rural Population in India

2018 ◽  
Vol 59 (4) ◽  
pp. 33 ◽  
Author(s):  
Butchibabu Kalakonda ◽  
RituPrabha Patel ◽  
Ramesh Amirisetty ◽  
NarendraVarma Penumatsa ◽  
Pradeep Koppolu
Keyword(s):  
Chronic Periodontitis ◽  
Rural Population ◽  
Gingival Crevicular Fluid ◽  
Interleukin 8 ◽  
Interleukin 1Β ◽  
Crevicular Fluid

scholarly journals Effect of Periodontal Therapy on Crevicular Fluid Interleukin-6 and Interleukin-8 Levels in Chronic Periodontitis

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Paschalina Goutoudi ◽  
Evdoxia Diza ◽  
Malamatenia Arvanitidou
Keyword(s):  
Interleukin 6 ◽  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Strong Relationship ◽  
Periodontal Therapy ◽  
Interleukin 8 ◽  
Treatment Modalities ◽  
Enzyme Linked Immunosorbent Assay ◽  
Nonsurgical Periodontal Therapy ◽  
Crevicular Fluid

Purpose. The aim of this study was to analyse the levels of interleukin-6 (IL-6) and interleukin-8 (IL-8) in gingival crevicular fluid (GCF) of patients with chronic periodontitis prior to and following surgical and/or nonsurgical periodontal therapy for a period of 32 weeks.Methods. GCF samples were obtained from 24 nondiseased and 72 diseased sites of 12 periodontal patients prior to as well as at 6, 16, and 32 weeks following non-surgical and surgical periodontal therapy. IL-6 and IL-8 levels were determined by enzyme-linked immunosorbent assay (ELISA).Results. Periodontal treatment improved all clinical parameters. Both treatment modalities resulted in similar IL-6 as well as IL-8 levels. Mean IL-6 and IL-8 concentrations were significantly higher in non-diseased compared to diseased sites and increased significantly following treatment in diseased sites. Mean total amounts of IL-6 and IL-8 (TAIL-6, TAIL-8) did not differ significantly between diseased and nondiseased sites, while following therapy TAIL-8 levels decreased significantly.Conclusions. The data suggest that periodontal therapy reduced the levels of IL-8 in GCF. However, a strong relationship between IL-6, IL-8 amounts in GCF and periodontal destruction and inflammation was not found.

Haplotypes of susceptibility to chronic periodontitis in the Interleukin 8 gene do not influence protein level in the gingival crevicular fluid

2012 ◽  
Vol 57 (10) ◽  
pp. 1355-1361 ◽  
Author(s):  
Sâmia C.T. Corbi ◽  
Giovana Anovazzi ◽  
Lívia S. Finoti ◽  
Yeon J. Kim ◽  
Marisa V. Capela ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Protein Level ◽  
Gingival Crevicular Fluid ◽  
Interleukin 8 ◽  
Crevicular Fluid

Gingival Crevicular Fluid Levels of Interleukin-1β and Glycemic Control in Patients With Chronic Periodontitis and Type 2 Diabetes

2004 ◽  
Vol 75 (9) ◽  
pp. 1203-1208 ◽  
Author(s):  
Steven P. Engebretson ◽  
Judith Hey-Hadavi ◽  
Fernando J. Ehrhardt ◽  
Dan Hsu ◽  
Romi S. Celenti ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Interleukin 1Β ◽  
Crevicular Fluid ◽  
Fluid Levels

scholarly journals Correlation of Levels of Interleukin-1β in Gingival Crevicular Fluid to the Clinical Parameters of Chronic Periodontitis

2011 ◽  
Vol 12 (1) ◽  
pp. 52-59 ◽  
Author(s):  
AU Chaudhari ◽  
GN Byakod ◽  
PF Waghmare ◽  
VM Karhadkar
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Healthy Subjects ◽  
Gingival Crevicular Fluid ◽  
Test Group ◽  
Interleukin 1Β ◽  
Clinical Parameters ◽  
Tissue Destruction ◽  
Tooth Mobility ◽  
Crevicular Fluid

ABSTRACT Aim Background and objectives: IL-1β is a potent stimulator of bone resorption and has been implicated in the pathogenesis of periodontal destruction. Therefore, this study was designed to compare the levels of IL-1β of chronic periodontitis patients with the healthy subjects. Another objective of this study was to correlate IL-1β levels with the clinical parameters of the periodontal disease progression. Methods For this study, total 60 subjects were chosen (30- healthy and 30-chronic periodontitis). Simplified oral hygiene index (OHI-S), gingival index (GI), periodontal disease index (PDI), probing depth (PD), tooth mobility, bleeding on probing (BOP) were recorded for all the subject. Gingival crevicular fluid (GCF) was collected and subjected for ELISA for estimation of IL-1β Results At the periodontal diseased sites, the IL-1β levels increased at least 2-fold as compared with healthy subjects. This increase was highly significant (p = 0.0000). Within the test group, IL-1β levels correlated positively and significantly with PDI, PD, BOP and tooth mobility. The correlations of IL-1β with PD (p = 0.000) and IL-1β with BOP (p = 0.0004) were highly significant. Interpretation and conclusion These data suggest that amount of GCF IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. Clinical significance It could be stated from this study on IL- 1β that there seem to be a strong correlation between periodontal tissue destruction and IL-1β. Furthermore IL-1β level could also differentiate between active and inactive periodontal lesions. How to cite this article Chaudhari AU, Byakod GN, Waghmare PF, Karhadkar VM. Correlation of Levels of Interleukin-1β in Gingival Crevicular Fluid to the Clinical Parameters of Chronic Periodontitis. J Contemp Dent Pract 2011;12(1):52-59.

Effects of Continuous and Interrupted Orthodontic Force on Interleukin-1β and Interleukin-8 Secretion in Human Gingival Crevicular Fluid

2008 ◽  
Vol 50 (4) ◽  
pp. 230-238
Author(s):  
Chidchanok Leethanakul ◽  
Chuleeporn Kittichaikarn ◽  
Chairat Charoemratrote ◽  
Suwanna Jitpukdeebodintra
Keyword(s):  
Gingival Crevicular Fluid ◽  
Interleukin 8 ◽  
Interleukin 1Β ◽  
Orthodontic Force ◽  
Crevicular Fluid
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