Evaluation of the effect of temperature on the potency of isophane insulin in a rat model

2020 ◽  
Vol 11 (1) ◽  
pp. 25
Author(s):  
Aniket Kumar ◽  
Deepasree Sukumaran ◽  
AruldhasBlessed Winston ◽  
Margaret Shanthi
Keyword(s):  
Rat Model ◽  
Effect Of Temperature ◽  
Isophane Insulin

Effect of temperature on the kinetics of lactate production and clearance in a rat model of forebrain ischemia

1998 ◽  
Vol 76 (2-3) ◽  
pp. 503-509 ◽  
Author(s):  
Hao Lei ◽  
James Peeling
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Rat Model ◽  
Brain Temperature ◽  
Lactate Production ◽  
Effect Of Temperature ◽  
Resonance Spectroscopy ◽  
Forebrain Ischemia ◽  
Vessel Occlusion ◽  
Kinetics Of

To investigate the effect of brain temperature on metabolic perturbations during and following forebrain ischemia, localized 1H magnetic resonance spectroscopy was used to measure the kinetics of lactate production and clearance in a rat model of 12- or 20-min forebrain ischemia (two-vessel occlusion with hypotension) at a brain temperature of either 34.5 ± 0.5°C or 37.5 ± 0.5°C. During ischemia, lactate production was modeled with apparent first order kinetics. Hypothermia did not affect the rate or the extent of lactate production during ischemia. Upon reperfusion, a delay in the decrease of the cerebral lactate level was found in the normothermia groups. Such a delay was absent in hypothermia groups, which may reflect faster resumption of cerebral oxidative metabolism upon reperfusion in the hypothermic animals. The rate constant for lactate clearance postischemia was larger for normothermic animals and for the 20-min ischemia groups, perhaps because of increased blood-brain barrier permeability following more severe ischemia.Key words: forebrain ischemia, temperature, hypothermia, lactate, magnetic resonance spectroscopy.

Nucleation of Disorder in Fe3Al Alloys

1967 ◽  
Vol 25 ◽  
pp. 312-313
Author(s):  
P. R. Swann ◽  
W. R. Duff ◽  
R. M. Fisher
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Annealing Temperature ◽  
Antiphase Domain ◽  
Effect Of Temperature ◽  
Domain Structures ◽  
Transmission Electron ◽  
Domain Boundaries ◽  
Higher Temperature ◽  
The One

Recently we have investigated the phase equilibria and antiphase domain structures of Fe-Al alloys containing from 18 to 50 at.% Al by transmission electron microscopy and Mössbauer techniques. This study has revealed that none of the published phase diagrams are correct, although the one proposed by Rimlinger agrees most closely with our results to be published separately. In this paper observations by transmission electron microscopy relating to the nucleation of disorder in Fe-24% Al will be described. Figure 1 shows the structure after heating this alloy to 776.6°C and quenching. The white areas are B2 micro-domains corresponding to regions of disorder which form at the annealing temperature and re-order during the quench. By examining specimens heated in a temperature gradient of 2°C/cm it is possible to determine the effect of temperature on the disordering reaction very precisely. It was found that disorder begins at existing antiphase domain boundaries but that at a slightly higher temperature (1°C) it also occurs by homogeneous nucleation within the domains. A small (∼ .01°C) further increase in temperature caused these micro-domains to completely fill the specimen.

The effect of temperature on high-resolution TEM image contrast

1995 ◽  
Vol 53 ◽  
pp. 640-641
Author(s):  
T. Geipel ◽  
W. Mader ◽  
P. Pirouz
Keyword(s):  
Form Factor ◽  
Inelastic Scattering ◽  
Accurate Method ◽  
Waller Factor ◽  
Effect Of Temperature ◽  
Specimen Thickness ◽  
Influence Of Temperature ◽  
Debye Waller Factor ◽  
Influence Of Temperature On ◽  
Atomic Form Factor

Temperature affects both elastic and inelastic scattering of electrons in a crystal. The Debye-Waller factor, B, describes the influence of temperature on the elastic scattering of electrons, whereas the imaginary part of the (complex) atomic form factor, fc = fr + ifi, describes the influence of temperature on the inelastic scattering of electrons (i.e. absorption). In HRTEM simulations, two possible ways to include absorption are: (i) an approximate method in which absorption is described by a phenomenological constant, μ, i.e. fi; - μfr, with the real part of the atomic form factor, fr, obtained from Hartree-Fock calculations, (ii) a more accurate method in which the absorptive components, fi of the atomic form factor are explicitly calculated. In this contribution, the inclusion of both the Debye-Waller factor and absorption on HRTEM images of a (Oll)-oriented GaAs crystal are presented (using the EMS software.Fig. 1 shows the the amplitudes and phases of the dominant 111 beams as a function of the specimen thickness, t, for the cases when μ = 0 (i.e. no absorption, solid line) and μ = 0.1 (with absorption, dashed line).

1045: Pioglitazone Ameliorates Penile Corpora Veno-Occlusive Dysfunction (CVOD) in a Rat Model of Type 2 Diabetes

2005 ◽  
Vol 173 (4S) ◽  
pp. 283-284
Author(s):  
Istvan Kovanecz ◽  
Monica G. Ferrini ◽  
Hugo H. Davila ◽  
Jacob Rajfer ◽  
Nestor F. Gonzalez-Cadavid
Keyword(s):  
Type 2 Diabetes ◽  
Rat Model

V1341: The Rat Model of Cavernous Nerve Injury: Practical Aspects

2005 ◽  
Vol 173 (4S) ◽  
pp. 364-365
Author(s):  
John F. Donohue ◽  
Michael Mullerad ◽  
Philip S. Li ◽  
Peter T. Scardino ◽  
John P. Mulhall
Keyword(s):  
Nerve Injury ◽  
Rat Model ◽  
Cavernous Nerve ◽  
Cavernous Nerve Injury

1441: Experimental Success of Biodegradable Conduit Graft for Regeneration and Reconnection of Transected Cavernous Nerves in a Rat Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 379-380
Author(s):  
Shinichi Hisasue ◽  
Ryuichi Kato ◽  
Yoshikazu Sato ◽  
Takahiro Suetomi ◽  
Atsushi Takahashi ◽  
...  
Keyword(s):  
Rat Model ◽  
Cavernous Nerves

1713: Effect of Botulinum Toxin on Overactive Bladder Contractions Induced by Intra Vesical ATP and Capsaicin in the RAT Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 453-453
Author(s):  
Humphrey O. Atiemo ◽  
Jacob Wynes ◽  
James Chuo ◽  
Lisa Nipkow ◽  
Geoffrey N. Sklar ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Overactive Bladder ◽  
Rat Model
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