Comparative efficacy of tea tree oil nanoemulgel and clove oil nanoemulgel against Candida albicans

2018 ◽  
Vol 8 (1) ◽  
pp. 50
Author(s):  
JasjeetKaur Narang ◽  
RamandeepSingh Narang ◽  
Balwinder Singh ◽  
SukhdeepS Kahlon ◽  
Jiji George ◽  
...  
2020 ◽  
Vol 34 ◽  
Author(s):  
Renata Serignoli FRANCISCONI ◽  
Patricia Milagros Maquera HUACHO ◽  
Caroline Coradi TONON ◽  
Ester Alves Ferreira BORDINI ◽  
Marília Ferreira CORREIA ◽  
...  

2021 ◽  
Vol 2063 (1) ◽  
pp. 012007
Author(s):  
Mahmood M. Fahad ◽  
Mohammed G.A. Al-Khuzaie

Abstract Due to the spread of the Corona pandemic, the demand for hand sanitizers has increased dramatically. This led to a global scarcity of sterilizers. Therefore, this study was performed to produce and evaluate the effectiveness of new commercially available, cheap and ethanol-free hand sanitizers from various sources. The new hand sanitizers were prepared by mixing (glycerin) as a moisturizer and (carbomer) as thickening agents to form the gel with (tri-ethanolamine base) as pH neutralizer and (Tea tree oil, Aloe vera extract or Povidone 10%) respectively as antiseptic agents. All prepared hand sanitizers were examined with four kinds of bacteria (Enterococcus faecalis, E. coli, Pseudomonas aeruginosa and Staphylococcus aureus) And two kinds of fungi (Candida albicans and Aspergillus flavus). The prepared hand sanitizer gels showed good sterilization efficacy and similar to commercially prepared hand sanitizers (70% ethanol).


2006 ◽  
Vol 28 (63) ◽  
Author(s):  
Diego Rodrigo Villanueva Macedo ◽  
Aline Mendes ◽  
Aline Ulbrich Mores ◽  
Magna Menezes de Carvalho Thiele ◽  
Rosimeire Takaki Rosa ◽  
...  

O presente estudo teve como objetivo avaliar a atividade antifúngica do extrato total de Melaleuca alternifolia.O extrato foi comparado com o digluconato de clorexidina em diferentes concentrações. Os testes foram realizados utilizando 46 cepas de Candida albicans colhidas de pacientes que usavam próteses totais e apresentavam ou não estomatite protética. O valor da concentração inibitória mínima (CIM) do óleo de Melaleuca foi de 1,25g/l (0,125%) para todas as cepas. A concentração candidicida mínima (CCM) foi de 0,125-0,25g/l (0,125-0,250%). Em comparação o digluconato de clorexidina apresentou uma CIM de 16mg/l para todas as cepas e a CCM foi de 16-32mg/l.


2000 ◽  
Vol 38 (5) ◽  
pp. 354-361 ◽  
Author(s):  
K. A. Hammer ◽  
C. F. Carson ◽  
T. V. Riley

2014 ◽  
Vol 61 (2) ◽  
Author(s):  
Katarzyna Rajkowska ◽  
Alina Kunicka-Styczyńska ◽  
Marta Maroszyńska ◽  
Mariola Dąbrowska

Members of Candida species cause significant problems in medicine and in many industrial branches also. In order to prevent from Candida sp. development, essential oils are more and more frequently applied as natural, non-toxic, non-pollutive and biodegradable agents with a broad spectrum of antimicrobial activity. The aim of the research was to determine changes in morphology and metabolic properties of Candida albicans in the presence of thyme and tea tree oils. Changes of enzymatic activity of isolates were observed in the presence of both tested essential oils, and they were primarily associated with loss or decrease of activity of all enzymes detected for control. Furthermore, only for 3 out of 11 isolates additional activity of N-acetyl-β-glucosaminidase, α-mannosidase, α-fucosidase and trypsin was detected. Vivid changes in biochemical profiles were found after treatment with tea tree oil and they were related to loss of ability to assimilate D-xylose, D-sorbitol and D-trehalose. The main differences in morphology of isolates compared to the control strain concerned formation of pseudohyphae structures. Both examined essential oils caused changes in cell and colony morphology, as well as in the metabolism of Candida albicans. However, the extent of differences depends on the type and concentration of an essential oil. The most important finding is the broad spectrum of changes in yeast enzymatic profiles induced by thyme and tea tree oils. It can be supposed that these changes, together with loss of ability to assimilate saccharides could significantly impact Candida albicans pathogenicity.


Author(s):  
Rayan Y. Booq ◽  
Abdullah A. Alshehri ◽  
Fahad A. Almughem ◽  
Nada M. Zaidan ◽  
Walaa S. Aburayan ◽  
...  

Hand hygiene is an essential factor to prevent or minimize the spread of infections. The ability to prepare an alcohol-free hand sanitizer (AFHS) with antimicrobial properties is crucial, especially during pandemics, when there are high demands and a low supply chain for ethanol and isopropanol. The objective of this study was to prepare AFHS gels based on natural materials that contain essential oils (EOs) that would be effective against a broad spectrum of pathogens. The results showed that the organoleptic characteristics of all prepared hand sanitizer gels were considered acceptable. The pH of the formulations was slightly acidic (circa 3.9) owing to the presence of aloe vera in large proportions (90% v/v), which is known for its acidity. The spreadability for all tested formulations was in the acceptable range. The antimicrobial effectiveness test demonstrated that the prepared hand sanitizer gels had antimicrobial activities against different gram-positive and gram-negative bacteria and Candida albicans yeast. The highest antibacterial effect was observed with tea tree oil hand sanitizers, which lack activity against the yeast, while clove oil hand sanitizers showed effectiveness against all microorganisms, including Candida albicans. The lavender hand sanitizer exhibited the least antimicrobial efficiency. The acceptability study on 20 human volunteers showed that the hand sanitizer gel containing 1.25% (v/v) clove oil did not produce any signs of skin irritation. This study suggested that the prepared natural hand sanitizer gel with 1.25% (v/v) clove oil can be a potential alternative to commonly used alcohol-based hand sanitizers (ABHS).


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