Corneal haze and densitometry in keratoconus after collagen cross-linking by three different protocols

AmaniE Badawi

doi:10.4103/joco.joco_145_21

Corneal haze and densitometry in keratoconus after collagen cross-linking by three different protocols

Journal of Current Ophthalmology ◽

10.4103/joco.joco_145_21 ◽

2021 ◽

Vol 33 (4) ◽

pp. 422

Author(s):

AmaniE Badawi

Keyword(s):

Cross Linking ◽

Corneal Haze ◽

Collagen Cross Linking

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Localised corneal haze and scarring following pulsed accelerated collagen cross-linking for keratoconus

Eye ◽

10.1038/s41433-018-0211-3 ◽

2018 ◽

Vol 33 (1) ◽

pp. 167-168

Author(s):

Dalia G Said ◽

Andrew R Ross ◽

Marco Messina ◽

Imran Mohammed ◽

Harminder S Dua

Keyword(s):

Cross Linking ◽

Corneal Haze ◽

Collagen Cross Linking

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Management of Corneal Ectasia after LASIK with Phototherapeutic Keratectomy Combined with Photorefractive Keratectomy and Collagen Cross-Linking

Journal of Ophthalmology ◽

10.1155/2019/2707826 ◽

2019 ◽

Vol 2019 ◽

pp. 1-7

Author(s):

Weiyan Zhou ◽

Hongya Wang ◽

Xiao Zhang ◽

Mingxia Tian ◽

Changxia Cui ◽

...

Keyword(s):

Visual Acuity ◽

Endothelial Cell ◽

Cell Count ◽

Cross Linking ◽

Spherical Equivalent ◽

Corneal Ectasia ◽

Corneal Haze ◽

Endothelial Cell Count ◽

Spherical Equivalent Refraction ◽

Collagen Cross Linking

Background. To evaluate the efficacy of phototherapeutic keratectomy (PTK) combined with photorefractive keratectomy (PRK) and riboflavin with ultraviolet-A collagen cross-linking (CXL), performed sequentially on the same day, in the management of corneal ectasia after LASIK. Methods. This retrospective review comprised consecutive patients with corneal ectasia after LASIK. The patients were administered PTK and PRK on the previous corneal flap, and CXL was given on the same day by the same surgeon. The main outcome measures included age, sex, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent refraction, cylinder equivalent refraction, steep and flat keratometries (K), central corneal thickness (CCT), endothelial cell count, corneal haze, and ectasia stability. Mean follow-up period was 6, 12, and 24 months. Results. Sixteen eyes of twelve patients were included in the study. Twenty-four months after administration of PTK combined with PRK and CXL, a significant improvement in UDVA was observed. Mean cylinder equivalent refraction was significantly reduced at 6, 12, and 24 months postoperatively. However, no significant reduction was observed in spherical equivalent refraction. A significant reduction in the flat K and steep K values was observed. No significant change in mean CCT value was observed. Mean endothelial cell count and morphology were unchanged between preoperative and postoperative patients. In addition, no obvious corneal haze was observed. Conclusions. PTK combined with PRK and CXL on the same day is a safe and effective treatment in improving visual acuity in selected patients with corneal ectasia after LASIK.

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