scholarly journals A study of serum magnesium level in type 2 diabetes mellitus and its association with glycemic control and its complications

2021 ◽  
Vol 6 (1) ◽  
pp. 34
Author(s):  
Arti Muley ◽  
Kalpesh Moradiya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Serum Magnesium ◽  
Magnesium Level ◽  
Serum Magnesium Level

scholarly journals Association of Serum Magnesium Deficiency with Insulin Resistance in Type 2 Diabetes Mellitus

2015 ◽  
Vol 7 (02) ◽  
pp. 075-078 ◽  
Author(s):  
Happy Chutia ◽  
Kyrshanlang G Lynrah
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Sensitivity ◽  
Serum Magnesium ◽  
Magnesium Level ◽  
Serum Magnesium Level ◽  
Sensitivity Indices

ABSTRACT Background: Insulin resistance (IR) is the key pathophysiological defect that leads to the development of type 2 diabetes mellitus. The purpose of this study was to estimate serum magnesium level and insulin sensitivity indices among type 2 diabetes mellitus patients and to see an association between them. Methods: This study was carried out among 38 type 2 diabetic patients and forty age and sex matched controls. Serum fasting glucose, magnesium, insulin, urea, and creatinine levels were estimated. Insulin sensitivity indices, homeostasis model assessment for insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI) levels were calculated as per formulae. Results: A highly significant low serum magnesium level was found in diabetic subjects as compared to the controls. Statistically significant high HOMA levels (>2.6) and low QUICKI levels (< 0.33) were found among the case group. An inverse, statistically significant correlation was found between serum magnesium and fasting insulin level. A highly statistically significant inverse correlation was found between serum magnesium and HOMA level, and a positive correlation was found between serum magnesium and QUICKI level, that is, serum magnesium level decreases with increase in IR. A strong association was also found between fasting serum insulin level and insulin sensitivity indices. Conclusion: This study showed a lower serum magnesium level in diabetic patients compared to control. A strong association was also found between serum magnesium level and insulin sensitivity indices. For proper management of type 2 diabetes, it may, therefore, be necessary to treat hypomagnesemia in these patients.

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