scholarly journals Effect of hyaluronic acid in modifying tensile strength of nonabsorbable suture materials: An in vitro study

Author(s):  
SudhirR Varma ◽  
Mohammed Jaber ◽  
SalimA Fanas ◽  
Vijay Desai ◽  
ArijM Al Razouk ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Mohammed Alsarhan ◽  
Hourya Alnofaie ◽  
Rawan Ateeq ◽  
Ahmed Almahdy

Background. Suturing plays a critical role in the healing of surgical wounds. The tensile strength of suture materials indicates the ability of the material to withstand stress during knotting and protect the wound during an extended period of healing. Objective. An in vitro study was conducted to determine the effect of two commercially available mouthwashes on the tensile strength and breakage mode of two absorbable intraoral sutures. Materials and Methods. Two common absorbable sutures, Vicryl® and Monocryl®, both with 4-0 and 5-0 gauges were used. A total of 400 specimens were sutured around rubber rods and immersed in three thermostatically controlled experimental conditions: artificial saliva, 0.2% chlorhexidine gluconate (Parodontax® extra), and essential oils-based rinse (Listerine® Zero™), and these were compared to a nonimmersed dry condition. All specimens were stored in an incubator at 37°C. Tensile strengths were assessed after days 1, 3, 7, 10, and 14 of immersion using a universal Instron® testing machine. The maximum load for suture breakage and the location of the point of breakage were assessed. Results. Unlike Monocryl® 4-0, the tensile strength of both gauges of Vicryl® sutures significantly increased in chlorhexidine and Listerine®. There was a significant decrease in the strength for all suture types after day 10, regardless of the immersion solution. Listerine® significantly reduced the tensile strength of Monocryl® 5-0. Conclusion. Oral surgeons and periodontists should be cautious when prescribing commercial mouthwashes for patients relative to their selection of suture materials. However, further studies are needed to understand the molecular changes in sutures when exposed to chemical solutions found in mouthwashes.


2018 ◽  
Vol 88 (2) ◽  
pp. 235-243 ◽  
Author(s):  
Mario Kreszinger ◽  
◽  
Bojan Toholj ◽  
Aleksandar Ačanski ◽  
Sebastijan Baloš ◽  
...  

2018 ◽  
Vol 1 (A4) ◽  
pp. 111-116
Author(s):  
R Saravanakumar ◽  
Minu P Mathew ◽  
B Pratebha ◽  
I Karthikeyan ◽  
Vineela Katam Reddy ◽  
...  

2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Munerah Binshabaib ◽  
Kawther Aabed ◽  
Fitoon Alotaibi ◽  
Milaf Alwaqid ◽  
Aljohara Alfraidy ◽  
...  

Objective: The aim of the present in-vitro study was to assess antimicrobial efficacy of 0.8% hyaluronic acid (HA) and 0.2% Chlorhexidine gluconate (CHX) against Porphyromonas gingivalis (P. gingivalis). Methods: The study was performed between December 2018 and March 2019 at the College of Dentistry at the Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia. The P. gingivalis biofilms were formed and grown for 72 hours at 37°C under anaerobic conditions on glass slides coated with human saliva. The slides were individually positioned and exposed to 0.8% HA or 0.2% CHX. Therapeutically, the biofilms were divided into 3 groups as follows: (a) negative group; (b) 0.8% HA group and (c) 0.2% CHX group. P-values less than 0.05 were considered statistically significant. Results: In the 0.8% HA group, P. gingivalis CFUs/ml were significantly higher at baseline than at 24- (P<0.05), 48 (P<0.05) and 72 hours (P<0.05) intervals. In the 0.2% CHX group, P. gingivalis CFUs/ml were significantly higher at baseline than at 72 hours interval (P<0.05). In the CHX group, there was no difference in P. gingivalis CFUs/ml between baseline, 24- and 48-hours intervals. At 48- and 72-hours intervals, the P. gingivalis CFUs/ml were significantly higher in the 0.2% CHX group compared with the 0.8% HA group. Conclusion: In-vitro, 0.8% HA is more effective in reducing the P. gingivalis CFUs/ml compared with 0.2% CHX. doi: https://doi.org/10.12669/pjms.36.2.1456 How to cite this:Binshabaib M, Aabed K, Alotaibi F, Alwaqid M, Alfraidy A, Alharthi S. Antimicrobial efficacy of 0.8% Hyaluronic Acid and 0.2% Chlorhexidine against Porphyromonas gingivalis strains: An in-vitro study. Pak J Med Sci. 2020;36(2):---------.   doi: https://doi.org/10.12669/pjms.36.2.1456 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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