scholarly journals Effectiveness of naturally derived bovine hydroxyapatite (Cerabone™) combined with platelet-rich fibrin matrix in socket preservation: A randomized controlled clinical trial

2019 ◽  
Vol 23 (2) ◽  
pp. 145 ◽  
Author(s):  
Suneetha Koneru ◽  
Prathyusha Kollati ◽  
ChinniDoraswamy Dwarakanath ◽  
SruthimaNaga Venkata Satya Gottumukkala
Keyword(s):  
Clinical Trial ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Socket Preservation ◽  
Platelet Rich Fibrin ◽  
Randomized Controlled ◽  
Fibrin Matrix ◽  
Bovine Hydroxyapatite

Platelet-rich fibrin as an alternative adjunct to tendon-exposed wound healing: A randomized controlled clinical trial

Burns ◽  
2019 ◽  
Vol 45 (5) ◽  
pp. 1152-1157 ◽  
Author(s):  
Shuang Zhang ◽  
DongSheng Cao ◽  
Juan Xie ◽  
HongHong Li ◽  
ZengHong Chen ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Wound Healing ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Platelet Rich Fibrin ◽  
Randomized Controlled

scholarly journals Randomized Controlled Clinical Trial of Nanostructured Carbonated Hydroxyapatite for Alveolar Bone Repair

Materials ◽  
2019 ◽  
Vol 12 (22) ◽  
pp. 3645 ◽  
Author(s):  
Rodrigo F. B. Resende ◽  
Suelen C. Sartoretto ◽  
Marcelo J. Uzeda ◽  
Adriana T. N. N. Alves ◽  
José A. Calasans-Maia ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Bone Repair ◽  
Alveolar Bone ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Double Blind ◽  
Socket Preservation ◽  
Carbonated Hydroxyapatite ◽  
Randomized Controlled

The properties of the biodegradation of bone substitutes in the dental socket after extraction is one of the goals of regenerative medicine. This double-blind, randomized, controlled clinical trial aimed to compare the effects of a new bioabsorbable nanostructured carbonated hydroxyapatite (CHA) with a commercially available bovine xenograft (Bio-Oss®) and clot (control group) in alveolar preservation. Thirty participants who required tooth extraction and implant placement were enrolled in this study. After 90 days, a sample of the grafted area was obtained for histological and histomorphometric evaluation and an implant was installed at the site. All surgical procedures were successfully carried out without complications and none of the patients were excluded. The samples revealed a statistically significant increase of new bone formation (NFB) in the CHA group compared with Bio-Oss® after 90 days from surgery (p < 0.05). However, the clot group presented no differences of NFB compared to CHA and Bio-Oss®. The CHA group presented less amount of reminiscent biomaterial compared to Bio-Oss®. Both biomaterials were considered osteoconductors, easy to handle, biocompatible, and suitable for alveolar filling. Nanostructured carbonated hydroxyapatite spheres promoted a higher biodegradation rate and is a promising biomaterial for alveolar socket preservation before implant treatment.

Sign in / Sign up

Export Citation Format

Share Document