scholarly journals Antibiotic resistance: Evaluation of levofloxacin treatment in acute respiratory tract infections cases at the Tasikmalaya City Health Center, Indonesia

Author(s):  
Danni Ramdhani ◽  
ShintaNur Azizah ◽  
SriAgung Fitri Kusuma ◽  
Dede Sediana
2020 ◽  
Vol 76 (4) ◽  
pp. 3-8
Author(s):  
Yu.V. Ponomareva ◽  
◽  
A.V. Ponomareva ◽  
V.I. Statsenko ◽  
V.I. Petrov ◽  
...  

This article contains information on the use of antibiotics according to the problem of antibiotic-resistance growth in pathogens of infections. Also suggested approaches to the choice and prescription of the rational antibiotic treatment of the most frequent respiratory tract infections in children in outpatient practice based on the modern Russian and Eurasian clinical guidelines.


2017 ◽  
Vol 32 (1) ◽  
Author(s):  
Makhtar Camara ◽  
Assane Dieng ◽  
Abdoulaye Diop ◽  
Amadou Diop ◽  
Amadou Diop ◽  
...  

<em>Background and aims.</em> <em>Streptococcus pneumoniae,</em> <em>Haemophilus influenzae</em> and <em>Moraxella</em> <em>catarrhalis</em> are the most common causative agents of acute respiratory tract infections (RTIs). The objective of this study was to assess their susceptibility to several antibiotics.<br /><em>Materials and methods</em>. A total of 58 strains (16 <em>S. pneumoniae</em>, 19 <em>H. influenzae</em> and 23 <em>M. catarrhalis</em>) were isolated from samples collected in two paediatric centres, and their susceptibility to commonly used antibiotics tested by E-test. <br /><em>Results</em>. Among <em>H. influenzae</em> isolates, 10.5% were resistant to ampicillin (all β-lactamase-positive), and 88.9% were susceptible to cefaclor. High β-lactam resistance rates (penicillin: 31.3% and cephalosporins: 18.7 to 31.3%) had been observed among <em>S</em>. <em>pneumonia</em> strains. Only 50% of isolates were susceptible to azithromycine. 91.3% of <em>M</em>. <em>catarrhalis</em> isolates β-lactamases producers were resistant to ampicillin while susceptible to the most tested antibiotics. <br /><em>Conclusions</em>. Except <em>M. catarrhalis</em> β-lactamases producing strains, frequency of antibiotic resistance was mainly observed among <em>S. pneumoniae,</em> and to a lesser extent among <em>H</em>. <em>influenzae</em> clinical isolates, suggesting the need for continuous surveillance of antimicrobial resistance patterns in the management of RTIs.


2019 ◽  
Vol 6 (1) ◽  
pp. 65-71
Author(s):  
Sulastini Sulastini ◽  
Sri Yekti Widadi ◽  
Desi Sentia ◽  
Bambang Aditya Nugraha

Acute respiratory tract infections is an acute infection caused by viruses, fungi and bacteria. Acute respiratory tract infections cases in Indonesia still rank first with a prevalence of 25% with malnutrition morbidity of 14.9%. In Garut District, the highest incidence of ARI was in Mekarwangi Health Center as many as 8004 cases and in 1840 children under five. While the prevalence of malnutrition or (thin) as many as 104 cases and 1 case of malnutrition. Nutritional status is a state of the body as a result of food consumption and use of nutrients. Differentiated between thin nutritional status, very thin, normal nutrition and fat nutrition. Nutritional status is one of the factors that play an important role in the health of children under five. If the nutritional status of under-fives or (underweight) toddlers will be susceptible to diseases, especially infectious diseases. The general objective of this study was to determine the relationship of nutritional status with the incidence of ARI in infants in Mekarwangi Garut Health Center in 2018. The type of research used was descriptive correlative, with a case control approach, a sample of 114 respondents divided into 57 case groups and 57 control groups. bivariate test analysis using chi-square. The results of the research on the nutritional status of most underweight children and half of children under five experienced acute respiratory tract infections. Conclusion there is a relationship between nutritional status with acute respiratory tract infections in infants in Mekarwangi Garut Public Health Center in 2018. It is recommended that health workers improve counseling to the public about the factors that affect acute respiratory tract infections  in order to be able to overcome and prevent, especially the problem of nutrition improvement.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Rafik Dey ◽  
Melanie A. Folkins ◽  
Nicholas J. Ashbolt

AbstractHuman respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infections in children and immunocompromised adults worldwide. Here we report that amoebae-release respirable-sized vesicles containing high concentrations of infectious RSV that persisted for the duration of the experiment. Given the ubiquity of amoebae in moist environments, our results suggest that extracellular amoebal-vesicles could contribute to the environmental persistence of respiratory viruses, including potential resistance to disinfection processes and thereby offering novel pathways for viral dissemination and transmission.


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