scholarly journals Bipolar herpes simplex infection in an human immunodeficiency virus-infected individual

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
CB Ravikumar ◽  
Sonia Raghukumar
Keyword(s):  
Human Immunodeficiency Virus ◽  
Herpes Simplex ◽  
Infected Individual ◽  
Herpes Simplex Infection ◽  
Simplex Infection ◽  
Immunodeficiency Virus

Generalized Herpes Simplex Infection in Neonatal Infant : A Report of Two Autopsy Cases†

1958 ◽  
Vol 8 (3) ◽  
pp. 251-262
Author(s):  
Kiyoyuki Kawai ◽  
Michio Arahama ◽  
Kiyoiychi Hirota ◽  
Masahiko Okudaira
Keyword(s):  
Herpes Simplex ◽  
Herpes Simplex Infection ◽  
Simplex Infection

scholarly journals 36 Experimental Genital Herpes Simplex infection in the Mouse

1967 ◽  
Vol 1 (3) ◽  
pp. 209-209 ◽  
Author(s):  
André J Nahmias ◽  
Zuher M Naib ◽  
Anita K Highsmith ◽  
William E Josey
Keyword(s):  
Herpes Simplex ◽  
Genital Herpes ◽  
Herpes Simplex Infection ◽  
Simplex Infection

Synergistic Antiviral Effects of Acyclovir and Vidarabine on Herpes simplex Infection in Newborn Mice

Chemotherapy ◽  
1985 ◽  
Vol 31 (4) ◽  
pp. 310-317 ◽  
Author(s):  
M.R. Karim ◽  
M.I. Marks ◽  
D.C. Benton ◽  
W. Rollerson
Keyword(s):  
Herpes Simplex ◽  
Herpes Simplex Infection ◽  
Newborn Mice ◽  
Antiviral Effects ◽  
Simplex Infection

scholarly journals Ontogeny and Specificities of Mucosal and Blood Human Immunodeficiency Virus Type 1-Specific CD8+ Cytotoxic T Lymphocytes

2003 ◽  
Vol 77 (1) ◽  
pp. 291-300 ◽  
Author(s):  
L. Musey ◽  
Y. Ding ◽  
J. Cao ◽  
J. Lee ◽  
C. Galloway ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Cytotoxic T Lymphocyte ◽  
Infected Individual ◽  
Immunodeficiency Virus ◽  
Hiv 1

ABSTRACT Induction of adaptive immunity to human immunodeficiency virus type 1 (HIV-1) at the mucosal site of transmission is poorly understood but crucial in devising strategies to control and prevent infection. To gain further understanding of HIV-1-specific T-cell mucosal immunity, we established HIV-1-specific CD8+ cytotoxic T-lymphocyte (CTL) cell lines and clones from the blood, cervix, rectum, and semen of 12 HIV-1-infected individuals and compared their specificities, cytolytic function, and T-cell receptor (TCR) clonotypes. Blood and mucosal CD8+ CTL had common HIV-1 epitope specificities and major histocompatibility complex restriction patterns. Moreover, both systemic and mucosal CTL lysed targets with similar efficiency, primarily through the perforin-dependent pathway in in vitro studies. Sequence analysis of the TCRβ VDJ region revealed in some cases identical HIV-1-specific CTL clones in different compartments in the same HIV-1-infected individual. These results clearly establish that a subset of blood and mucosal HIV-1-specific CTL can have a common origin and can traffic between anatomically distinct compartments. Thus, these effectors can provide immune surveillance at the mucosa, where rapid responses are needed to contain HIV-1 infection.

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