scholarly journals Comparison of sensitivities of skin prick and intradermal tests with oral rechallenge test: A prospective interventional hospital-based study

2021 ◽  
Vol 66 (1) ◽  
pp. 55
Author(s):  
Ayushi Bohara ◽  
SatyendraK Singh ◽  
Tulika Rai
Keyword(s):  
Intradermal Tests

Sensitivity of bovine tuberculosis surveillance through intradermal tests in cattle in France: an evaluation of different scenarios

2021 ◽  
pp. 105364
Author(s):  
Viviane Hénaux ◽  
Claire Ponsart ◽  
Justine Corre ◽  
Florence Etore ◽  
Henri-Jean Boulouis ◽  
...  
Keyword(s):  
Bovine Tuberculosis ◽  
Intradermal Tests

Systemic reaction during intradermal skin tests with beta-lactams

2021 ◽  
Vol 14 (3) ◽  
pp. e240050
Author(s):  
Joana Carvalho ◽  
Georgeta Oliveira
Keyword(s):  
Skin Testing ◽  
Drug Hypersensitivity ◽  
Systemic Reaction ◽  
Skin Tests ◽  
Beta Lactam ◽  
Provocation Tests ◽  
Maculopapular Eruption ◽  
Intradermal Tests ◽  
Amoxicillin Clavulanate ◽  
Immediate Reactions

Beta-lactam (BL) antibiotics are the most frequent cause of drug hypersensitivity in children, inducing both immediate and non-immediate reactions. Here we report a case of a 4-year-old child with a disseminated maculopapular exanthema 7 days after the first dose of amoxicillin–clavulanate, referred to our paediatric allergy department. Skin prick tests were negative. Intradermal tests were performed and, after 10 hours, indurated wheals larger than 10×10 mm with progressive erythema and disseminated maculopapular eruption were developed, related to amoxicillin and amoxicillin–clavulanate. Systemic reactions to BL skin tests are rarely reported and the majority are immediate reactions. This case illustrates a rare example of a non-immediate systemic reaction to intradermal tests, underlying the importance of skin testing before drug provocation tests in cases of moderate to severe non-immediate reactions.

Immunologic Defects in Patients With Refractory Sinusitis

PEDIATRICS ◽  
1991 ◽  
Vol 87 (3) ◽  
pp. 311-316 ◽  
Author(s):  
Gail G. Shapiro ◽  
Frank S. Virant ◽  
Clifton T. Furukawa ◽  
William E. Pierson ◽  
C. Warren Bierman
Keyword(s):  
Poor Response ◽  
Etiologic Factor ◽  
Vaccine Response ◽  
Sinus Disease ◽  
Intradermal Tests ◽  
Pneumococcal Antigen ◽  
Common Problems ◽  
Clinically Significant ◽  
Immunoglobulin Levels ◽  
Recurrent Otitis Media

Sixty-one patients with chronic sinusitis who were referred for an allergy evaluation were evaluated for immunologic competence including assessment of quantitative serum immunoglobulin levels, IgG subclass levels, and response to pneumococcal and Haemophilus influenzae vaccines. In addition to chronic sinus disease, recurrent otitis media and asthma exacerbation were common problems in this group. Five patients had an elevated age-adjusted IgE level and 22 patients had positive prick tests to one or more environmental inhalants; these findings suggest an allergic component in this subgroup. Twelve additional patients had highly reactive intradermal tests to common environmental allergens, which also may be clinically significant for underlying atopy. Eleven patients had low immunoglobulin levels, 6 had low immunologlobulin levels and vaccine hyporesponsiveness, and 17 had poor vaccine response only. Thus, 34 of 61 patients with refractory sinusitis had abnormal results on immune studies, with depressed IgG3 levels and poor response to pneumococcal antigen 7 being most common. In addition to allergy, immunologic incompetence may be an important etiologic factor in patients with chronic, refractory sinusitis.

Meglumine antimoniate-induced DRESS: original case with a positive skin test

2018 ◽  
Vol 63 (4) ◽  
pp. 845-847 ◽  
Author(s):  
Amel Chaabane ◽  
Haifa Ben Romdhane ◽  
Hajer Ben Brahim ◽  
Nadia Ben Fredj ◽  
Zohra Chadli ◽  
...  
Keyword(s):  
Skin Test ◽  
Clinical Picture ◽  
Drug Withdrawal ◽  
Skin Tests ◽  
Positive Skin ◽  
Meglumine Antimoniate ◽  
Blood Tests ◽  
Intradermal Tests ◽  
Original Case ◽  
Hepatic Cytolysis

Abstract We report a case of a 64-year-old woman treated with meglumine antimoniate (Glucantime®). On day 20, she developed fever, a pruriginous skin rash and myalgia. The blood tests showed eosinophilia and hepatic cytolysis. The clinico-biological picture improved gradually and the symptoms disappeared 4 weeks after the drug withdrawal. Six weeks later, intradermal tests to Glucantime® were performed and were positive at 48 hour-reading. This clinical picture suggests DRESS induced by meglumine antimoniate. To the best of our knowledge, only one case of meglumine antimoniate-induced DRESS has been reported in the literature and we are the first to report a case confirmed by skin tests.

Prediction of postpartum purulent-septic complications using intradermal tests

1986 ◽  
Vol 67 (4) ◽  
pp. 275-276
Author(s):  
Z. D. Karimov ◽  
L. P. Bakuleva ◽  
M. F. Yakutina ◽  
A. A. Nesterova ◽  
S. V. Nazarova ◽  
...  
Keyword(s):  
T Cell ◽  
Functional Assessment ◽  
T Cell Immunity ◽  
Septic Complications ◽  
Cell Immunity ◽  
Intradermal Tests ◽  
Inner Surface

Intradermal tests for functional assessment of T-cell immunity were performed on 95 women who gave birth. There were 39 women aged 19 to 24 years, 25 to 29 to 36, and 30 to 35 to 20. Bacterial allergens were injected at a dose of 0.1 ml on the inner surface of the forearm strictly intradermally at 7-8 cm apart. The results were evaluated after 24 h. The reaction was considered positive if the size of the infiltrate was equal or greater than 8 mm.

scholarly journals Skin Reactions to Intradermal Neuromuscular Blocking Agent Injections

2007 ◽  
Vol 107 (2) ◽  
pp. 245-252 ◽  
Author(s):  
Paul Michel Mertes ◽  
Denise Anne Moneret-Vautrin ◽  
Francisque Leynadier ◽  
Marie-Claire Laxenaire
Keyword(s):  
Blocking Agent ◽  
Diagnostic Value ◽  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Agent ◽  
Slight Reduction ◽  
Maximal Concentration ◽  
Skin Reactions ◽  
Intradermal Tests ◽  
To Receive ◽  
Positive Results

Background Numerous reports confirm the performance of intradermal tests for the diagnosis of anaphylaxis during anesthesia; however, there is controversy over their diagnostic value regarding the newer neuromuscular blocking agents (NMBAs). Methods One hundred eleven healthy volunteers were randomly assigned to receive intradermal injections of two NMBAs, at five increasing concentrations. A concentration was considered as a reactive concentration when it led to a positive reaction in more than 5% of the subjects. These concentrations were compared with the maximal concentration recommended for the diagnosis of sensitization to NMBAs. Results The maximal nonreactive concentrations were 10 m for suxamethonium; 10 m for pancuronium, vecuronium, rocuronium, and cisatracurium; and 10 m for atracurium and mivacurium. Except for mivacurium, these nonreactive concentrations were close to the maximal concentrations used for the diagnosis of sensitization against NMBAs. For mivacurium, the nonreactive concentrations were higher than the maximal concentration currently recommended in clinical practice. Conclusion The aminosteroidal NMBAs pancuronium, vecuronium, and rocuronium and the benzylisoquinoline cisatracurium have a similar potency to induce a nonspecific skin reactivity. If the criteria for positivity and the maximal concentrations of the commercially available compounds recommended by French practice guidelines are used, the risk of false-positive results is limited, and only minor modifications of these recommendations could be suggested. A slight reduction in the maximal concentration used for rocuronium from 1:100 to 1:200 and an increase from 1:1,000 to 1:200 for mivacurium can be proposed.

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