scholarly journals A diagnostic challenge of invasive sellar neuroaspergillosis in an immunocompetent patient

2021 ◽  
Vol 54 (3) ◽  
pp. 111
Author(s):  
Pranita Mohanty ◽  
Anasuya Lenka ◽  
T Govardhan ◽  
Souvagya Panigrahi
Keyword(s):  
Immunocompetent Patient ◽  
Diagnostic Challenge

‘Lipo-tourism’ gone wrong: blood transfusion-transmitted cytomegalovirus disease

2021 ◽  
Vol 14 (3) ◽  
pp. e236892
Author(s):  
Mark Brahier ◽  
Rhanika Neuda ◽  
William Davis ◽  
Rita Poon
Keyword(s):  
Blood Transfusion ◽  
Medical Tourism ◽  
Wound Dehiscence ◽  
Immunocompetent Patient ◽  
Cytomegalovirus Disease ◽  
Diagnostic Challenge ◽  
Risks And Benefits ◽  
Life Threatening ◽  
Cmv Disease

Medical tourism is the pursuit of more affordable surgeries; however, this comes at the risk of suboptimal standards and potential for life-threatening complications. In this case, we describe the diagnostic challenge of cytomegalovirus (CMV) pneumonia in a 40-year-old woman who experienced wound dehiscence and subsequent blood transfusion-transmitted CMV as complications of liposuction in the Dominican Republic. We explore the role of histopathology in the diagnosis of disseminated CMV, discuss the underlying aetiology of CMV pneumonia in this patient and weigh the risks and benefits of initiating antiviral therapy in an immunocompetent patient with CMV disease.

scholarly journals Diagnostic challenge between Crohn's disease and intestinal tuberculosis in chronic diarrhea with ulcerated jejunal stenosis: a case report

2020 ◽  
Vol 40 (4) ◽  
pp. 346
Author(s):  
Valeria Costa-Barney ◽  
Andrés F. Delgado-Villarreal ◽  
Ana María Leguízamo ◽  
Rómulo Darío Vargas
Keyword(s):  
Weight Loss ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Chronic Diarrhea ◽  
Intestinal Tuberculosis ◽  
Immunocompetent Patient ◽  
Diagnostic Challenge ◽  
Correct Treatment ◽  
Antituberculosis Treatment ◽  
Patient At Risk

Intestinal tuberculosis and Crohn's disease are a diagnostic challenge because of the clinical, radiological and endoscopic similarity. The histological and microbiological findings are positive in less than 50%, which delays the correct treatment, putting the patient at risk. We reported a 34-year-old immunocompetent patient with 4 years of malabsorptive diarrhea, weight loss, nocturnal diaphoresis, abdominal pain and an ulcer with stenosis in the jejunum was found; she mpirical antituberculosis treatment with clinical improvement. Later the culture was positive for M. tuberculosis.

Invasive aspergillosis of the skull base in an immunocompetent patient: a diagnostic challenge

2021 ◽  
Vol 14 (11) ◽  
pp. e245517
Author(s):  
Alexandra Borges ◽  
Lìgia Ferreira ◽  
Ricardo Pacheco ◽  
Isabel Fonseca
Keyword(s):  
Skull Base ◽  
Fungal Infections ◽  
Immunocompetent Patient ◽  
Imaging Features ◽  
Round Cell ◽  
Diagnostic Challenge ◽  
Small Round Cell ◽  
Tropical Climates ◽  
Small Round Cell Tumour ◽  
Immunocompetent Patients

We describe the case of a 32-year-old man from Cape Verde having headache and increasing visual loss. Clinical and radiological investigations disclosed a massive destructive lesion involving the anterior and central skull base, orbit and nasoethmoid region initially interpreted as a malignant small round cell tumour. Surgical biopsies were negative for neoplasm, showing an intense inflammatory infiltrate together with fungus, later characterised as Aspergillus flavus spp. The patient was immunocompetent with no evidence of congenital or acquired immunodeficiencies. Invasive fungal infections in immunocompetent patients are rare and can be a diagnostic challenge. The best diagnostic clues include the patient’s origin from tropical climates, imaging features and the identification of fungal hyphae on pathology specimens. Although a devastating disease in immunocompromised patients, craniocerebral aspergillosis in immunocompetent patients carries a better prognosis. Available literature supports the combined used of ‘conservative’ surgical resection and antifungal therapy as the best treatment option.

scholarly journals Central Nervous System Vasculitis for Cryptococcosis in an Immunocompetent Patient

Diseases ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 75 ◽  
Author(s):  
Dan Zimelewicz Oberman ◽  
Liliana Patrucco ◽  
Carolina Cuello Oderiz
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cryptococcus Neoformans ◽  
Cryptococcal Meningitis ◽  
Fungal Pathogen ◽  
Immunocompetent Patient ◽  
Central Nervous System Vasculitis ◽  
Diagnostic Challenge ◽  
Threatening Condition ◽  
Life Threatening

Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, Cryptococcus neoformans, that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient patients. However, in an immunocompetent patient it represents a diagnostic challenge, mainly because it is extremely rare, but also because of its nonspecific clinical manifestation. Neurovascular involvement in cryptococcal meningitis is rare and not well known and only few reports have described this association. We describe a cryptococcal meningitis in an immunocompetent patient associated with central nervous system vasculitis.

scholarly journals Hepatic Candidiasis in an Immunocompetent Patient: A Diagnostic Challenge

Cureus ◽  
2021 ◽  
Author(s):  
Zorays Moazzam ◽  
Amman Yousaf ◽  
Zahid Iqbal ◽  
Ahmad Tayyab ◽  
Muhammad Hashim Hayat
Keyword(s):  
Immunocompetent Patient ◽  
Diagnostic Challenge

scholarly journals Isolated Retropancreatic Tuberculous Lymphadenitis Mimicking Carcinoma: A Diagnostic Challenge

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
H. Kuriry ◽  
R. Alenezi ◽  
A. Alghamdi ◽  
A. M. Swied
Keyword(s):  
Weight Loss ◽  
Lymph Node ◽  
Obstructive Jaundice ◽  
Unusual Case ◽  
Immunocompetent Patient ◽  
Tuberculous Lymphadenitis ◽  
Rare Entity ◽  
Diagnostic Challenge ◽  
First Case ◽  
The Common

Tuberculosis as a cause of obstructive jaundice is a rare entity with only a few cases reported in the literature. Patients with this condition usually present with a protracted illness, jaundice, and weight loss, which may be confused with malignancies. We are reporting unusual case of isolated enlarged tuberculous lymph node compressing the common bile duct in the retropancreatic region and causing obstructive jaundice in an immunocompetent patient which to the best of our knowledge is the first case of isolated retropancreatic tuberculous lymphadenitis in Saudi Arabia.

scholarly journals Lupus Vulgaris: A Diagnostic Challenge

2021 ◽  
Vol 79 (1) ◽  
pp. 75-77
Author(s):  
Hisabella Lorena Simões Porto ◽  
Isabela Alves Guerra ◽  
Barbara Figueiredo Bastos ◽  
Marina Ferreira ◽  
Marcelino Pereira Martins Neto ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Mycobacterium Tuberculosis Complex ◽  
Immunocompetent Patient ◽  
Tuberculosis Complex ◽  
Lupus Vulgaris ◽  
Diagnostic Challenge ◽  
Cutaneous Tuberculosis ◽  
Important Differential Diagnosis ◽  
Clinical Variant ◽  
The Face

Lupus vulgaris is a clinical variant of cutaneous tuberculosis, a rare subtype of extrapulmonary infection caused by the Mycobacterium tuberculosis complex. A paucibacillary form associated with high degrees of immunity, predominantly in the face, may present several clinical and histopathological differential diagnoses, which makes its diagnosis challenging. We present a case of lupus vulgaris in an immunocompetent patient, whose initial clinical presentation and histopathology did not suggest the condition. The objective is to highlight the relevance of the hypothesis of cutaneous tuberculosis as an important differential diagnosis, especially in endemic areas.

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