scholarly journals Macroscopic on-site evaluation of biopsy specimens for accurate pathological diagnosis during EUS-guided fine needle biopsy using 22-G Franseen needle

2020 ◽  
Vol 9 (6) ◽  
pp. 385
Author(s):  
Hirotoshi Ishiwatari ◽  
Junichi Kaneko ◽  
Keiko Sasaki ◽  
Tatsunori Satoh ◽  
Junya Sato ◽  
...  
2021 ◽  
Vol 10 (2) ◽  
pp. 111
Author(s):  
Dong-Wan Seo ◽  
Hoonsub So ◽  
JunSeong Hwang ◽  
SungWoo Ko ◽  
Dongwook Oh ◽  
...  

2019 ◽  
Vol 8 (5) ◽  
pp. 342 ◽  
Author(s):  
Dong-Wan Seo ◽  
Dongwook Oh ◽  
Seung-Mo Hong ◽  
TaeJun Song ◽  
DoHyun Park ◽  
...  

2019 ◽  
Vol 07 (02) ◽  
pp. E189-E194 ◽  
Author(s):  
En-Ling Leung Ki ◽  
Anne-Isabelle Lemaistre ◽  
Fabien Fumex ◽  
Rodica Gincul ◽  
Christine Lefort ◽  
...  

Abstract Background and aims This study aimed to evaluate the performance of Macroscopic On-site Evaluation (MOSE) using a novel endoscopic ultrasound (EUS) fine needle biopsy (FNB) needle (22-G Franseen-tip needle, Acquire, Boston Scientific Incorporated, Boston, Massachusetts, United States), and without using Rapid On-Site Evaluation (ROSE). Method Between May 2016 and August 2016, all consecutive patients referred to our center for EUS tissue acquisition (TA) for solid lesions underwent EUS-FNB with the 22-G Franseen-tip needle unless contra-indicated. The operator performed MOSE. If no macroscopic core was visualized, a second pass was performed. The final diagnosis was defined as unequivocal histology from EUS-TA with compatible 18 months follow-up, surgical resection, or both. We retrospectively analyzed the performance of MOSE. Results A total of 46 consecutive patients was included, and 54 solid lesions were biopsied. The endosonographer visualized core tissue in 93 % (50/54) of targets with a single pass, of which the pathologist confirmed histologic core fragments in 94 % (47/50). Four lesions required two passes, and the overall correlation between MOSE and histologic core fragments was 94 % (48/51). Diagnostic adequacy was 98 % (53/54) with one biliary target biopsied without significant material. The overall diagnostic accuracy was 94 %. Sensitivity, specificity, positive predictive value, and negative predictive value for malignancy were 92 %, 100 %, 100 %, and 81 %, respectively. No adverse events were reported. Conclusion Our study demonstrated that MOSE using the 22-G Franseen-tip needle could limit needle passes by accurately estimating histologic core fragments. It also demonstrated that high diagnostic adequacy and accuracy of > 90 % could be achieved without ROSE.


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