Renal-protective effect of dexmedetomidine during cardiac surgery with cardiopulmonary bypass: a prospective, randomized, double-blind, placebo-controlled study

2019 ◽  
Vol 13 (3) ◽  
pp. 45
Author(s):  
AhmedM Abd El-Hamid ◽  
DinaH Elbarbary
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Protective Effect ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

A Phase II, Double-Blind, Placebo-Controlled, Ascending-Dose Study of Eritoran (E5564), a Lipid A Antagonist, in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass

2007 ◽  
Vol 104 (2) ◽  
pp. 378-383 ◽  
Author(s):  
Elliott Bennett-Guerrero ◽  
Hilary P. Grocott ◽  
Jerrold H. Levy ◽  
Kevin A. Stierer ◽  
Charles W. Hogue ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Phase Ii ◽  
Lipid A ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Dose Study

AMIODARONE TO REDUCE POST-CARDIOPULMONARY BYPASS SIRS - A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED STUDY

2004 ◽  
Vol 32 (Supplement) ◽  
pp. A43
Author(s):  
Georg Delle Karth ◽  
Anton Buberl ◽  
Brigitte Meyer ◽  
Gerlinde Zorn ◽  
Johann Wojta ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Post Cardiopulmonary Bypass

Effects of Intravenous Famotidine on Gastric Acid Secretion in Patients Undergoing Cardiac Surgery

1995 ◽  
Vol 29 (4) ◽  
pp. 349-353 ◽  
Author(s):  
Bertil KJ Wagner ◽  
David W Amory ◽  
Claudine M Majcher ◽  
Louis T DiFazio ◽  
Gregory E Scott ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Gastric Ph ◽  
University Teaching ◽  
Controlled Study ◽  
Double Blind ◽  
Elective Cardiac Surgery

Objective: To determine the effects of cardiopulmonary bypass and famotidine on gastric acid secretion in adults undergoing cardiac surgery. Design: Prospective, randomized, double-blind, placebo-controlled study. Setting: University teaching hospital. Participants: Eighteen patients undergoing elective cardiac surgery with cardiopulmonary bypass. Main Outcome Measures: Famotidine 20 mg or NaCl 0.9% placebo was administered intravenously following induction of anesthesia and placement of a nasogastric pH probe. A second dose was given 12 hours after surgery in the intensive care unit. Gastric pH was measured continuously and gastric volume was measured every 4 hours for up to 24 hours after cardiopulmonary bypass. Results: Following famotidine administration, pH increased by 43% within 45 minutes and remained above 5.5 throughout the study period (p < 0.05 vs placebo and baseline). The gastric pH did not increase, but remained above 4.0 in most patients in the placebo group for up to 12 hours after cardiopulmonary bypass. Gastric volumes were on average 24% lower in the famotidine group (p > 0.05). Conclusions: Gastric acid secretion is decreased during and for 12 hours after cardiopulmonary bypass. Perioperative administration of famotidine suppresses gastric secretion in cardiac surgery patients.

Dexamethasone Decreases the Incidence of Shivering After Cardiac Surgery: a Randomized, Double-Blind, Placebo-Controlled Study

1999 ◽  
Vol 43 (3) ◽  
pp. 127-128
Author(s):  
JEAN-PIERRE YARED ◽  
NORMAN J. STARR ◽  
LORI HOFFMAN-HOGG ◽  
ALLEN C. BASHOUR ◽  
STEVEN R. INSLER ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo
Sign in / Sign up

Export Citation Format

Share Document