Acylated and unacylated ghrelin relieve cancer cachexia in mice through multiple mechanisms

2020 ◽  
Vol 63 (5) ◽  
pp. 195
Author(s):  
Sizeng Chen ◽  
Xianliang Zeng ◽  
Ping Chen ◽  
Li Zhao
Keyword(s):  
Cancer Cachexia ◽  
Unacylated Ghrelin

Therapeutic Exercise in Cancer Cachexia

2012 ◽  
Vol 17 (3) ◽  
pp. 285-292 ◽  
Author(s):  
Matthew Maddocks ◽  
Andrew J. Murton ◽  
Andrew Wilcock
Keyword(s):  
Cancer Cachexia ◽  
Therapeutic Exercise

Diversity-Oriented Synthetic Approaches for Furoindoline: A Review

2019 ◽  
Vol 16 (3) ◽  
pp. 342-368 ◽  
Author(s):  
Ramandeep Kaur ◽  
Yagyesh Kapoor ◽  
Sundeep K. Manjal ◽  
Ravindra K. Rawal ◽  
Kapil Kumar
Keyword(s):  
Rheumatoid Arthritis ◽  
Cancer Cachexia ◽  
Biological Activities ◽  
Ring System ◽  
Synthetic Methods ◽  
Structural Units ◽  
Current Article ◽  
Tetrahydropyranyl Ether ◽  
Synthetic Approaches ◽  
Synthetic Target

The furo [2,3-b] indoline ring system is one of the most important structural units in various natural products. It has been known to have inherent biological activities and is utilized as a synthetic target for a number of natural compounds; therefore, this has contributed to a great demand for the growth of synthetic methods for this ring system. Most important compounds with furoindoline ring system are physovenine, madindoline A and B and makomotindoline etc. These compounds are well known to exhibit biological activity against different diseases such as glaucoma, cancer, cachexia, Castleman’s disease, rheumatoid arthritis, etc. The current article focuses on various synthetic approaches for furoindoline containing compounds and essential furoindoline moiety, such as oxindole-5-O-tetrahydropyranyl ether route etc., and various other diastereoand enantio- controlled approach in a very concise way.

Inhibition of HSP90 reverses STAT3‐mediated muscle wasting in cancer cachexia mice

2021 ◽  
Author(s):  
Mengyuan Niu ◽  
Shiyu Song ◽  
Zhonglan Su ◽  
Lulu Wei ◽  
Li Li ◽  
...  
Keyword(s):  
Cancer Cachexia ◽  
Muscle Wasting
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