scholarly journals Optimal pressure in penile rehabilitation with a vacuum erection device: evidence based on a rat model

2019 ◽  
Vol 21 (5) ◽  
pp. 516 ◽  
Author(s):  
Jiu-Hong Yuan ◽  
Xing-Liang Yang ◽  
Yang Yang ◽  
Fu-Dong Fu ◽  
Chang-Jing Wu ◽  
...  
Keyword(s):  
Rat Model ◽  
Evidence Based ◽  
Vacuum Erection Device ◽  
Penile Rehabilitation

scholarly journals Phosphodiesterase-5 Inhibitors and Vacuum Erection Device for Penile Rehabilitation After Laparoscopic Nerve-Preserving Radical Proctectomy for Rectal Cancer: A Prospective Controlled Trial

2016 ◽  
Vol 11 (3) ◽  
pp. 641-646 ◽  
Author(s):  
Haijun Deng ◽  
Dong Liu ◽  
Xiangming Mao ◽  
Xiaoliang Lan ◽  
Hao Liu ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Erectile Function ◽  
Therapy Group ◽  
Controlled Trial ◽  
Combined Therapy ◽  
Intervention Group ◽  
Phosphodiesterase Type 5 Inhibitors ◽  
The Mean ◽  
Vacuum Erection Device ◽  
Penile Rehabilitation

The current study sought to clarify the role of phosphodiesterase type 5 inhibitors (PDE-5i) and a vacuum erection device (VED) in penile rehabilitation after laparoscopic nerve-preserving radical proctectomy (LNRP) for rectal cancer. Participants were assigned to one of the following arms—no-intervention, nightly use of sildenafil 25 mg for 3 months after surgery, or concurrent use of nightly sildenafil 25 mg/day for 3 months and a vacuum erection device (VED) 10 to 15 minutes/day for 3 months—in a nonrandomized fashion. All participants had a follow-up of over 12 months prospectively, and patients had baseline, 3-, 6-, and 12-month assessment based on the International Index of Erectile Function–5 (IIEF-5). Seventy-one cases were included in final analyses. In the no-intervention group, the mean baseline IIEF-5 score of 21.9 decreased rapidly to 5.0 at 3 months ( p < .001), 9.2 at 6 months ( p < .001), and stayed at 10.9 at 12 months ( p < .001). In the single therapy group, the mean baseline IIEF-5 score of 22.4 decreased dramatically to 9.0 at 3 months ( p < .001), 14.9 at 6 months ( p = .005), and stayed at 15.1 at 12 months ( p = .005). In the combined therapy group, the mean baseline IIEF-5 score of 23.0 decreased slightly to 15.0 at 3 months ( p = .005), 18.0 at 6 months ( p = .038), and maintained at 18.7 at 12 months ( p = .163). Findings suggested an over 50% decline in the quality of erection function of the patients after LNRP. The early use of PDE-5i alone or combined use of PDE-5i and VED after LNRP maintained erectile function at 12 months.

scholarly journals Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty

2019 ◽  
Vol 21 (6) ◽  
pp. 582 ◽  
Author(s):  
Qiang Fu ◽  
Lu-Jie Song ◽  
Dong-Liang Zhang ◽  
Zhong Chen ◽  
Fei-Xiang Wang ◽  
...  
Keyword(s):  
Vacuum Erection Device ◽  
Penile Rehabilitation

An Evidence-Based Review of Micro-CT Assessments of the Postmenopausal Osteoporosis Rat Model

2015 ◽  
Vol 11 (3) ◽  
pp. 177-200 ◽  
Author(s):  
Nadia Mohd Effendy ◽  
Nurul Izzah Ibrahim ◽  
Norazlina Mohamed ◽  
Ahmad Nazrun Shuid
Keyword(s):  
Postmenopausal Osteoporosis ◽  
Rat Model ◽  
Evidence Based ◽  
Micro Ct

Reduction in Peyronie's-like plaque size using a vacuum erection device in a rat model of Peyronie's disease via the TGF-β/SMAD signalling pathway

Andrologia ◽  
2018 ◽  
Vol 50 (7) ◽  
pp. e13051 ◽  
Author(s):  
Jinhong Li ◽  
Shuzhen Wang ◽  
Feng Qin ◽  
Mengli Zhu ◽  
Xuanhe You ◽  
...  
Keyword(s):  
Rat Model ◽  
Peyronie’S Disease ◽  
Signalling Pathway ◽  
Plaque Size ◽  
Peyronie's Disease ◽  
Vacuum Erection Device

Optimal vacuum erectile device therapy regimen for penile rehabilitation in a bilateral cavernous nerve crush rat model

Andrology ◽  
2021 ◽  
Author(s):  
Ming Ma ◽  
Feng Qin ◽  
Changjing Wu ◽  
Wenfeng Xiong ◽  
Botao Yu ◽  
...  
Keyword(s):  
Rat Model ◽  
Device Therapy ◽  
Nerve Crush ◽  
Cavernous Nerve ◽  
Therapy Regimen ◽  
Penile Rehabilitation

Of rats and men: A narrative journey

2006 ◽  
Vol 4 (2) ◽  
pp. 197-199
Author(s):  
KATHLEEN BABA WILLISON
Keyword(s):  
Palliative Care ◽  
Rat Model ◽  
Evidence Based

Palliative care clinicians are often challenged in this evidence-based world to find studies that are generalizable to our population. And yet, there is much to be learned from the unique situations that we encounter. This narrative reflects upon the application of palliative principles to one special rat model.

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