scholarly journals The synergistic effect of tranexamic acid and ethamsylate combination on blood loss in pediatric cardiac surgery

2021 ◽  
Vol 24 (1) ◽  
pp. 17
Author(s):  
IbrahimI. Abd El Baser ◽  
HanaaM ElBendary ◽  
Ahmad ElDerie
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Synergistic Effect ◽  
Tranexamic Acid ◽  
Pediatric Cardiac Surgery

scholarly journals Effect of tranexamic acid on blood loss in pediatric cardiac surgery: a randomized trial

2011 ◽  
Vol 25 (6) ◽  
pp. 823-830 ◽  
Author(s):  
Kazuyoshi Shimizu ◽  
Yuichiro Toda ◽  
Tatsuo Iwasaki ◽  
Mamoru Takeuchi ◽  
Hiroshi Morimatsu ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Randomized Trial ◽  
Pediatric Cardiac Surgery

Hemostatic Parameters and Platelet Activation Marker Expression in Cyanotic and Acyanotic Pediatric Patients Undergoing Cardiac Surgery in the Presence of Tranexamic Acid

2000 ◽  
Vol 83 (01) ◽  
pp. 54-59 ◽  
Author(s):  
Elena Levin ◽  
John Wu ◽  
John Alexander ◽  
Clayton Reichart ◽  
Suvro Sett ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Platelet Activation ◽  
Pediatric Patients ◽  
Factor Xiiia ◽  
Congenital Defects ◽  
Plasma Factor ◽  
Pai 1 ◽  
D Dimer

SummaryWe have investigated hemostatic parameters including platelet activation in 56 pediatric patients with or without cyanosis undergoing cardiopulmonary bypass (CPB) and cardiac surgery to repair congenital defects. Patients were participants in a study assessing the effects of tranexamic acid on surgery-related blood loss. Parameters monitored included blood loss, prothrombin F1.2, thrombin-antithrombin complexes, t-PA, PAI-1, plasminogen, fibrin D-dimer, and plasma factor XIII. Additionally, flow cytometry monitored platelet degranulation (P-selectin or CD63), as well as surface-bound fibrinogen, von Willebrand factor and factor XIIIa. Cyanotic patients had evidence of supranormal coagulation activation as both fibrin D-dimer and PAI-1 levels were elevated prior to surgery. While the extent of expression of Pselectin or CD63 was not informative, platelet-associated factor XIIIa was elevated in cyanotic patients at baseline. In both patient groups, CPB altered platelet activation state and coagulation status irrespective of the use of tranexamic acid.

The Influence of Aprotinin and Tranexamic Acid on Platelet Function and Postoperative Blood Loss in Cardiac Surgery

2008 ◽  
Vol 107 (2) ◽  
pp. 391-397 ◽  
Author(s):  
Andinet M. Mengistu ◽  
Kerstin D. Röhm ◽  
Joachim Boldt ◽  
Jochen Mayer ◽  
Stefan W. Suttner ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Platelet Function ◽  
Postoperative Blood Loss

The Efficacy of Tranexamic Acid Versus Placebo in Decreasing Blood Loss in Pediatric Patients Undergoing Repeat Cardiac Surgery

1997 ◽  
Vol 84 (5) ◽  
pp. 990-996 ◽  
Author(s):  
Robert W. Reid ◽  
A. Andrew Zimmerman ◽  
Peter C. Laussen ◽  
John E. Mayer ◽  
Jed B. Gorlin ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Pediatric Patients ◽  
Acid Versus

Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery

2004 ◽  
Vol 18 (2) ◽  
pp. 141-143 ◽  
Author(s):  
Sandeep Chauhan ◽  
Sambhu N Das ◽  
Akshay Bisoi ◽  
Shailaja Kale ◽  
Usha Kiran
Keyword(s):  
Cardiac Surgery ◽  
Tranexamic Acid ◽  
Aminocaproic Acid ◽  
Pediatric Cardiac Surgery ◽  
Epsilon Aminocaproic Acid

The effect of three different doses of tranexamic acid on blood loss after cardiac surgery with mild systemic hypothermia (32°C)

1998 ◽  
Vol 12 (6) ◽  
pp. 642-646 ◽  
Author(s):  
Jacek M. Karski ◽  
Noreen P. Dowd ◽  
Ross Joiner ◽  
Jo Carroll ◽  
Charles Peniston ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Systemic Hypothermia ◽  
Different Doses

The Efficacy of Tranexamic Acid Versus Placebo in Decreasing Blood Loss in Pediatric Patients Undergoing Repeat Cardiac Surgery

1998 ◽  
Vol 42 (3) ◽  
pp. 146
Author(s):  
ROBERT W. REID ◽  
A. ANDREW ZIMMERMAN ◽  
PETER C. LAUSSEN ◽  
JOHN E. MAYER ◽  
JED B. GORLIN ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Pediatric Patients ◽  
Acid Versus
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