scholarly journals Successful medical management of fungal infective endocarditis post VSD closure

2021 ◽  
Vol 24 (1) ◽  
pp. 95
Author(s):  
Banashree Mandal ◽  
KallaKrishna Prasad Gourav ◽  
AnandKumar Mishra ◽  
VKrishna Narayanan Nayanar
Keyword(s):  
Infective Endocarditis ◽  
Medical Management

scholarly journals Medical management of infective endocarditis; Limitations and indication for surgery.

1985 ◽  
Vol 49 (5) ◽  
pp. 535-544 ◽  
Author(s):  
YOSHINORI KOGA ◽  
JUN-ICHI SHIBATA ◽  
TAKEHIKO YAMASAKI ◽  
YASUO OHKITA ◽  
HIRONORI TOSHIMA
Keyword(s):  
Infective Endocarditis ◽  
Medical Management ◽  
Indication For Surgery

P2764Medical management of Staphylococcus aureus infective endocarditis: unexpectedly favourable outcomes in an aggressive disease

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
C P Primus ◽  
M McCue ◽  
I Bvekerwa ◽  
E McGuire ◽  
K Wong ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Infective Endocarditis ◽  
Medical Management ◽  
Surgical Intervention ◽  
Electronic Device ◽  
Significant Proportion ◽  
Venous Catheter ◽  
Similar Proportion ◽  
Tissue Destruction ◽  
Improved Outcomes

Abstract Introduction Early surgical intervention (ESI) for infective endocarditis (IE) is associated with improved outcomes. Staphylococcus aureus endocarditis (SAE) is associated with particularly high rates of tissue destruction, morbidity and mortality. However, the question as to whether ESI is mandated in all SAE continues to be debated, in both native (NVE) and prosthetic (PVE) endocarditis. Methods Retrospective review of all IE cases presenting to our institution from October 2015 to January 2019. IE was diagnosed following imaging and microbiological protocols as per ESC guidance, and data were extracted for those with SAE. Patients with isolated cardiac implantable electronic device IE or bacteraemia secondary to indwelling long-term venous catheter infection were excluded (non-valvular IE). Results Valvular IE was diagnosed in 411 patients overall; NVE in 286 (69.6%) and PVE in 125 (30.4%). S aureus was isolated in 111 patients (28.1%), of whom 5 had a Methicillin-resistant strain. SAE was confirmed in a similar proportion of NVE and PVE cases [83/111 (74.8%) and 28/111 (25.2%), respectively]. Surgical intervention was mandated in 35/83 with NVE (42.2%) and 11/28 (39.3%) with PVE, lower than in our overall cohort (55.9% and 48.8%, respectively). In-hospital SAE mortality was 16.2% overall (18.4% medical vs 13.0% surgical), and contributes a significant proportion to overall mortality (29% to medical & 26% to surgical mortality). Figure 1 identifies the cause of death per mode of treatment, highlighting the aggressive nature of S aureus infection (abscess, disseminated infection and septic shock; n=8), the importance of advanced non-cardiac comorbidity precluding intervention (n=3) and ongoing intravenous drug use in those with PVE (n=4). However, medical management was successful in 57.8% (38/83) of NVE and 60.7% (17/28) of PVE cases, both in hospital and to a minimum follow-up of 3-months. Conclusion Staphylococcus aureus is virulent and highly pathogenic, driving severe sepsis and advanced tissue destruction in SAE. Despite this, medical management can be successful when following international guidance, but requires co-ordinated care driven by a multidisciplinary IE team at a cardiothoracic centre.

Early versus late surgical intervention or medical management for infective endocarditis: a systematic review and meta-analysis

Heart ◽  
2016 ◽  
Vol 102 (12) ◽  
pp. 950-957 ◽  
Author(s):  
Mahesh Anantha Narayanan ◽  
Toufik Mahfood Haddad ◽  
Andre C Kalil ◽  
Arun Kanmanthareddy ◽  
Rakesh M Suri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Infective Endocarditis ◽  
Medical Management ◽  
Surgical Intervention ◽  
Meta Analysis

scholarly journals Endovascular Management of Infective Intracranial Aneurysms with Acrylic Glue

2009 ◽  
Vol 15 (4) ◽  
pp. 443-447 ◽  
Author(s):  
A. Bhattacharyya ◽  
S. Mittal ◽  
R.R. Yadav ◽  
K. Jain ◽  
B. Gupta ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Endovascular Treatment ◽  
Medical Management ◽  
Intracranial Aneurysms ◽  
Good Prognosis ◽  
Endovascular Management ◽  
Significant Morbidity ◽  
Liquid Embolic ◽  
Mycotic Aneurysms ◽  
Acrylic Glue

Cerebral mycotic aneurysms (MAs) also called infective aneurysms, are uncommon and are usually encountered in patients with infective endocarditis. These aneurysms often present with intracranial hemorrhage. MAs may resolve on treatment with antibiotics alone. However prognosis with medical management alone is unpredictable. Good prognosis with surgery has been reported for single accessible ruptured MAs. However surgery is associated with significant morbidity. Endovascular treatment of MAs along with appropriate antibiotics is emerging as an acceptable option for these patients. We describe two cases of infective endocarditis complicated by ruptured MA treated successfully by liquid embolic glue material.

Sign in / Sign up

Export Citation Format

Share Document