scholarly journals Comparison of thromboelastography with routine laboratory coagulation parameters to assess the hemostatic profile and prognosticate postoperative critically ill patients

2021 ◽  
Vol 24 (1) ◽  
pp. 12
Author(s):  
Amrita Bhattacharyya ◽  
Prabhat Tewari ◽  
Devendra Gupta
2015 ◽  
Vol 45 (1) ◽  
pp. 90-93 ◽  
Author(s):  
Christina Routsi ◽  
Stelios Kokkoris ◽  
Evangelia Douka ◽  
Foteini Ekonomidou ◽  
Ilias Karaiskos ◽  
...  

2016 ◽  
Vol 12 (1) ◽  
pp. 63-67
Author(s):  
Masuma Ahmed Salsabil ◽  
Md Manirul Islam ◽  
Jannatul Ferdous ◽  
Shameem Montasir Hossain

Introduction: Haematological status is an important parameter for the management of critically ill patients. Objective: To see the status of the haematological changes of critically ill patients admitted in CMH, Dhaka. Materials and Methods: This cross sectional study was conducted in the Department of Haematology of Armed Forces Institute of Pathology and Intensive Care Unit of Combined Military Hospital, Dhaka from March 2014 to September 2014 for a period of 6 months. All the patients who were admitted in the Intensive Care Unit of Combined Military Hospital, Dhaka at any age with either sex were included in this study. The complete blood count and coagulation parameters were considered and data sheet was prepared. Results: A total number of 862 samples were analyzed. Male female ratio was 1.8:1. Anaemia was found in 43.2% patients and 22.3% patients had Erythrocytosis. Normocytic Normochromic Anaemia was the most common morphological subtype of Anaemia. 13.8% patients had Leukopenia and 55.1% patients had Leukocytosis; 7.3% patients had Neutropenia and 49.0% patients had Neutrophilia. 10.0% patients had Eosinophilia. 26.3% patients had Lymphopenia and 14.7% patients had Lymphocytosis. 39.1% patients had Thombocytopenia and 20.3% patients had Thrombocytosis. MCV (Mean Corpuscular Volume) was below normal in 36.5% patients and was above normal in 16.8% patients. MCH (Mean Corpuscular Hemoglobin) was below normal among 49.7% patients and 11.1% patients above normal. MCHC (Mean Corpuscular Haemoglobin Content) was below normal level in 61.8% patients and 3.7% patients had above normal. Abnormal coagulation parameters that is prolonged PT, APTT and raised FDP was found in 36.3%, 18.6% and 35.8% patients. Conclusion: Critically ill patients were suffering from anaemia and thrombocytopenia with significant changes in other blood cells counts and coagulation parameters. Journal of Armed Forces Medical College Bangladesh Vol.12(1) 2016: 63-67


Hepatology ◽  
2016 ◽  
Vol 64 (2) ◽  
pp. 556-568 ◽  
Author(s):  
Andreas Drolz ◽  
Thomas Horvatits ◽  
Kevin Roedl ◽  
Karoline Rutter ◽  
Katharina Staufer ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Ioannis Ilias ◽  
Aristidis Diamantopoulos ◽  
Efthymia Botoula ◽  
Nikolaos Athanasiou ◽  
Alexandros Zacharis ◽  
...  

ObjectiveWe aimed to measure insulin-like growth factor 1 (IGF1) and growth hormone (GH) in critically and non-critically ill patients with Covid-19 and assess them vis-a-vis clinical and laboratory parameters and prognostic tools.Subjects and MethodsWe included patients who were admitted to the wards or the ICU of the largest Covid-19 referral hospital in Greece; patients with non-Covid-19 pneumonia served as controls. Apart from the routine laboratory work-up for Covid-19 we measured GH and IGF1 (and calculated normalized IGF-1 values as standard deviation scores; SDS), after blood sampling upon admission to the wards or the ICU.ResultsWe studied 209 critically and non-critically ill patients with Covid-19 and 39 control patients. Patients with Covid-19 who were ICU non-survivors were older and presented with a worse hematological/biochemical profile (including white blood cell count, troponin, glucose, aminotransferases and lactate dehydrogenase) compared to ICU survivors or Covid-19 survivors in the wards. Overall, IGF-1 SDS was higher in Covid-19 survivors compared to non-survivors (-0.96 ± 1.89 vs -2.05 ± 2.48, respectively, p=0.030). No significant differences were noted in GH between the groups. Nevertheless, in critically ill patients with Covid-19, the prognostic value of IGF-1 (raw data), IGF-1 (SDS) and GH for survival/non-survival was on a par with that of APACHE II and SOFA (with a marginal difference between GH and SOFA).ConclusionIn conclusion, our findings suggest that there might be an association between low IGF1 (and possibly GH) and poor outcome in patients with Covid-19.


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