scholarly journals The effect of hypothyroidism on serum irisin level in patients with nondiabetic chronic kidney disease: A pilot study with a cross-sectional design

2018 ◽  
Vol 29 (4) ◽  
pp. 911
Author(s):  
JayaPrakash Sahoo ◽  
MilindMachhindra Patil ◽  
Sreejith Parameswaran ◽  
Sadishkumar Kamalanathan ◽  
Karthik Balachandran ◽  
...  
2021 ◽  
Vol 7 (3) ◽  
pp. 147-152
Author(s):  
Nur Syamsi ◽  
Andi Alfia Muthmainnah Tanra ◽  
Mariani Rasjid HS

The chronic kidney disease is a global health problem with increasing prevalence and incidence and a poor prognosis. Therefore, those brought about by risk factors are primarily those which can be modified and controlled for their occurrence.  One of the risk factor is smoking habit. The objective of this study was to determine the associations between smoking and renal function profiles in PT.X employees. The study was conducted by using descriptive analytical study with a cross sectional design based on smoking habits and blood test samples of employees. The sample were 40 employees in PT.X which determined by consecutive sampling. The results showed that there were no associations between smoking with age (p = 0.222) and azotemia (p = 1.00) but there were associations between smoking and blood creatinine levels (p = 0.001), urea (p = 0.023), eGFR (p. = 0.001), and the stages of chronic kidney disease (p = 0.047).  Based on the study results, in can be concluded that there were associations between smoking and renal function profiles among employees of PT. X


Author(s):  
Bokun Kim ◽  
Hyuntae Park ◽  
Gwonmin Kim ◽  
Tomonori Isobe ◽  
Takeji Sakae ◽  
...  

This cross-sectional pilot study aimed to assess the relationships of fat and muscle mass with chronic kidney disease (CKD) in older adults. Serum creatinine concentration was used to measure estimated glomerular filtration rate (mL/min/1.73 m2) in the 236 subjects, who were allocated to three groups: a normal (≥60.0), a mild CKD (45.0–59.9), and a moderate to severe CKD (<45.0) group. The Jonckheere-Terpstra test and multivariate logistic regression were employed to assess body composition trends and the relationships of % fat mass (FM) or % muscle mass index (MMI) with moderate-to-severe CKD. Body weight, fat-free mass, MMI, and %MMI tended to decrease with an increase in the severity of CKD, but the opposite trend was identified for %FM. No relationship with BMI was identified. The participants in the middle-high and highest quartile for %FM were 6.55 and 14.31 times more likely to have moderate to severe CKD. Conversely, the participants in the highest quartile for %MMI were 0.07 times less likely to have moderate to severe CKD. Thus, high fat and low muscle mass may be more strongly associated with CKD than obesity per se.


2017 ◽  
Vol 1 (01) ◽  
pp. 23
Author(s):  
Umi Faza ◽  
Dyah Umiyarni Purnamasari ◽  
Saryono Yono

Abstract  The aim of this study was to determine factors associated with diminished appetite in CKD patients undergoing hemodialysis therapy. This study is an observational analytic research with cross sectional design. Population of this study was CKD outpatients undergoing hemodialysis therapy in July- August 2016 in Prof. Dr. Margono Soekarjo Hospitals. Amount of 58 subjects taken by consecutive sampling. Appetite, sex, age, length of hemodialysis, frequency of nausea/vomiting, and depression were measured using questionnaire. Subjects who diminished appetite were 58,6%. More than half subjects were male (56,9%). Amount of 84,5% subjects were adults (19-59 years), 63,8% undergoing hemodialysis >1year, 39,7% experienced nausea/ vomiting and 53,4% were depression. Based on Chi-Square Test/ Fisher Exact Test, diminished appetite significantly associated with length of hemodialysis (p=0,041), frequency of nausea/vomiting (p=0,014), and depression (p=0,002). Dominant factors affected diminished appetite were depression and length of hemodialysis. Diminished appetite in CKD patients undergoing hemodialysis therapy associated with length of hemodialysis, frequency of nausea/vomit, and depression. Keyword : appetite, chronic kidney disease, hemodialysi  Abstrak Penelitian ini bertujuan untuk mengetahui faktor- faktor yang berhubungan dengan penurunan nafsu makan pada pasien Gagal Ginjal Kronik (GGK) yang menjalani terapi hemodialisis. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Populasi dari penelitian ini adalah pasien GGK rawat jalan yang menjalani terapi hemodialisis pada bulan Juli- Agustus 2016 di RSUD Prof. Dr. Margono Soekarjo Purwokerto. Sebanyak 58 subjek diambil dengan cara consecutive sampling. Nafsu makan, jenis kelamin, usia, lama hemodialisis, frekuensi mual/muntah, dan depresi diukur menggunakan kuesioner. Responden yang mengalami penurunan nafsu makan sebanyak 58,6%. Lebih dari separuh responden (56,9%) berjenis kelamin laki- laki dan 84,5% responden berusia dewasa (19-59 tahun). Sebanyak 63,8% responden menjalani hemodialisis >1tahun. Responden yang mengalami mual/muntah berat sebanyak 39,7% dan 53,4% mengalami depresi. Berdasarkan analisis bivariat menggunakan Uji Chi- Square/ Fisher Exact diperoleh hasil bahwa nafsu makan berhubungan secara signifikan dengan lama hemodialisis (p=0,041), frekuensi mual/ muntah (p=0,014), dan depresi (p=0,002). Faktor dominan yang mempengaruhi penurunan nafsu makan adalah depresi dan lama hemodialisis. Penurunan nafsu makan pada pasien GGK yang menjalani terapi hemodialisis berhubungan dengan lama hemodialisis, frekuensi mual/muntah, dan depresi. Kata kunci : gagal ginjal, hemodialisa, nafsu makan  


2015 ◽  
Vol 1 (4) ◽  
pp. 19-23 ◽  
Author(s):  
D Mishra ◽  
P Koirala

Chronic kidney disease is a worldwide public health problem. In Nepal, Chronic kidney disease patients are increasing and the management of this disease is very expensive compared to other chronic diseases? We assessed the socioeconomic status of chronic kidney disease patients registered in National Kidney Centre, Banasthali, Kathmandu. The study used descriptive cross sectional design. Ninety six samples were collected between 15- 31 October, 2012.The mean age of the patients was 47 years, with almost half of the patients (46%) from 41-60 years age group. Among the patients, 65 % were male, 85% were married, 80% were literate, 57% were past smoker and 75% were drinker and 59% were from Kathmandu valley. Likewise, most of them were Newar, work as housewife as the main occupation. One third (37%) had to sell their property for the treatment. On an average patient spent Rs.240000 per year in dialysis. Similarly, medication cost was Rs.180000 and transplantation cost was Rs.500000 to 1000000. Preventive measures of the disease and subsidy in the treatment will be beneficial for the needy people. DOI: http://dx.doi.org/10.3126/jmmihs.v1i4.11997Journal of Manmohan Memorial Institute of Health Sciences Vol. 1, Issue 4, 2015Page : 19-23 


2021 ◽  
Vol 31 (3) ◽  
pp. 139
Author(s):  
Epa Danisa Surbakti ◽  
Fasihah Irfani Fitri ◽  
Aldy Safruddin Rambe

<p>Chronic kidney disease (CKD) is an independent risk factor for cognitive impairment in all domains, especially delayed memory and executive function. The purpose of this study was to determine the correlation between chronic kidney disease severity and cognitive function. This study used a cross-sectional design in stage III, IV, and V CKD patients in the Nephrology Polyclinic of Haji Adam Malik Central General Hospital. Cognitive function tests were performed using the Montreal Cognitive Assessment (MoCA INA), digit span, and Trail Making Test A &amp; B. The Spearman test was used to analyze the correlation between CKD severity and cognitive function. This study involved 45 chronic kidney disease patients consisting of 28 (62.2%) males and 17 (37.8%) females with a mean age of 49.67±12.18 years. The results of statistical analysis showed that there was a significant positive correlation between CKD on the MoCA-INA examination (r=0.618, p=&lt;0.001), FDS (r=0.414, p=0.005), there was a significant negative correlation on the TMT A time examination (r=-0.425, p=0.004), TMT A error (r=-0.497, p=0.001), TMT B time (r=-0.618, p=&lt;0.001), TMT B error (r=-0.370, p=0.012). The results of this study prove a significant correlation between the severity of CKD and cognitive function.</p>


Author(s):  
Arif Wicaksono ◽  
Muhammad Sajidin

Hemodialysis therapy of patients with chronic kidney disease can changes the patients physically, psychological, social and economics because they have to deal with it for the rest of their life. This can affect the quality of life of the patients because of the long-term of hemodialysis therapy, this is one of the factors that affect the quality of life of the patients with chronic kidney disease. Quality of life is focused on the assessment of the individual against conditions acceptance. Each individual takes different phases to accept the condition. The purposes of the study were to determine if the relationship between the duration of hemodialysis and quality of life of the patients with chronic kidney disease at Gatoel Hospital Mojokerto. This research used cross-sectional design. The patient's population with chronic kidney disease undergoing hemodialysis is 150 people. The research sample is drawn using sampling techniques with the type of nonprobability purposive sampling with 130 people as a sample. Data obtained from questionnaires KDQoL 36. The result using Spearman rho test using SPSS V.16 shows p < α (0,006 < 0,05). H0 rejected, this means that there is a relationship between the duration of hemodialysis and quality of life with chronic kidney disease at Gatoel Hospital Mojokerto. The quality of life of the patients fluctuated based on the stage adaptation of the hemodialysis and disease. However, most patients with the duration of hemodialysis for more than 12 months had a sufficient quality of life and their therapy are already familiar with the symptoms and complications, but there are other factors that affect the quality of life such as gender, marital status, and education level. Patients are also expected to cooperate in what to do and not to do to improve the quality of life of the patients.


Author(s):  
Arif Wicaksono ◽  
Muhammad Sajidin

Hemodialysis therapy of patients with chronic kidney disease can changes the patients physically, psychological, social and economics because they have to deal with it for the rest of their life. This can affect the quality of life of the patients because of the long-term of hemodialysis therapy, this is one of the factors that affect the quality of life of the patients with chronic kidney disease. Quality of life is focused on the assessment of the individual against conditions acceptance. Each individual takes different phases to accept the condition. The purposes of the study were to determine if the relationship between the duration of hemodialysis and quality of life of the patients with chronic kidney disease at Gatoel Hospital Mojokerto. This research used cross-sectional design. The patient's population with chronic kidney disease undergoing hemodialysis is 150 people. The research sample is drawn using sampling techniques with the type of nonprobability purposive sampling with 130 people as a sample. Data obtained from questionnaires KDQoL 36. The result using Spearman rho test using SPSS V.16 shows p < α (0,006 < 0,05). H0 rejected, this means that there is a relationship between the duration of hemodialysis and quality of life with chronic kidney disease at Gatoel Hospital Mojokerto. The quality of life of the patients fluctuated based on the stage adaptation of the hemodialysis and disease. However, most patients with the duration of hemodialysis for more than 12 months had a sufficient quality of life and their therapy are already familiar with the symptoms and complications, but there are other factors that affect the quality of life such as gender, marital status, and education level. Patients are also expected to cooperate in what to do and not to do to improve the quality of life of the patients.


Renal Failure ◽  
2015 ◽  
Vol 37 (5) ◽  
pp. 757-762 ◽  
Author(s):  
Nigar Sekercioglu ◽  
Bryan Curtis ◽  
Sean Murphy ◽  
Brendan Barrett

2019 ◽  
Vol 6 (1) ◽  
pp. 1-12
Author(s):  
Fatchurozak Himawan ◽  
Anggorowati Anggorowati ◽  
Shofa Chasani

Patients with chronic kidney disease (CKD) undergoing haemodialysis require fulfilment of physical, psychological and spiritual needs. In the effort to meet the spiritual needs, it is necessary to do an appropriate spiritual needs assessment of the patients. Assessing a Patient’s Spiritual Needs (APSN) and Spiritual Needs Questionnaire Scale (SpNQ) are such available instruments for use in spiritual assessment. This study aimed to determine the spiritual needs of patients with chronic kidney disease undergoing haemodialysis using the APSN and SpNQ instruments. This study used a quantitative observation with a cross-sectional design. The samples were 104 patients undergoing haemodialysis for more than three months at Kardinah Hospital and RSUI Harapan Anda Kota Tegal. The results showed that the need of prayers was the highest spiritual needs in APSN in the dimension ‘divine’ as reported by 80 respondents (76.92%). Meanwhile, in SpNQ, the dimension of religiosity was rated the highest with 98 respondents (94.23%). Patients with CKD had spiritual needs in all dimensions both in APSN and SpNQ. The result of chi-square test showed a p-value of 0.170, indicating that there was no difference in the assessment of spiritual needs of patients using the APSN and SpNQ instruments. The APSN and SpNQ instruments could be further considered as alternative instruments to assess the spiritual needs of patients with CKD undergoing haemodialysis.


2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Emil Huriani ◽  
Elvia Donny Harida ◽  
Feri Fernandes

Objective:  to identify anxiety and compliance relationships with quality of life in patients with chronic kidney disease undergoing hemodialysis.Methods:  The research applied cross sectional design with 66 respondents. Analysis of research results using Chi-Square with a degree of significance p≤0,05.Results:  The results showed a significant relationship between anxiety and compliance with patient's quality of life.Conclusion:  It is important to optimize nursing care for anxiety that aims to improve the quality of life of patients with chronic kidney disease.


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