Tuberculosis-associated immune reconstitution inflammatory syndrome: Management challenges in resource-limited settings

2012 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
MukhtarA Adeiza
Keyword(s):  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Resource Limited Settings ◽  
Resource Limited ◽  
Inflammatory Syndrome

scholarly journals Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Kartik Natrajan ◽  
Mahenderkumar Medisetty ◽  
Raviraj Gawali ◽  
Ajit Tambolkar ◽  
Divya Patel ◽  
...  
Keyword(s):  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Immunocompromised Host ◽  
Strongyloides Stercoralis ◽  
Parasitic Infections ◽  
Infected Female ◽  
Resource Limited ◽  
Hyperinfection Syndrome ◽  
Advanced Hiv Disease ◽  
Inflammatory Syndrome

Parasitic infections such as Strongyloides stercoralis and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, S. stercoralis can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Immune reconstitution inflammatory syndrome (IRIS) developing after initiation of antiretroviral therapy (ART) can target multiple pathogens including S. stercoralis. The authors present here a 46-year-old HIV-infected female who was recently diagnosed with HIV-1 infection, started ART, and developed SHS. Her upper GI endoscopy revealed severe gastroduodenitis, and X-ray chest showed extensive bilateral pneumonitis. We could identify S. stercoralis in induced sputum and duodenal biopsy. We could also identify gut inflammation to restrict invading parasites. After receiving antihelminthic therapy, she showed improvement, a course of events that fit the diagnosis of unmasking S. stercoralis IRIS.

scholarly journals Immune reconstitution inflammatory syndrome among adolescents: A report of cases in a resource-limited setting (Uganda)

2010 ◽  
Vol 11 (2) ◽  
Author(s):  
Christine Katusiime ◽  
Ponsiano Ocama ◽  
Andrew Kambugu
Keyword(s):  
Young Adults ◽  
Infectious Diseases ◽  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Resource Limited Setting ◽  
Resource Limited ◽  
Inflammatory Syndrome ◽  
Limited Setting

We report immune reconstitution inflammatory syndromes in a cohort of adolescents/young adults over a period of 1 year at the Infectious Diseases Institute, Kampala, Uganda.

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