Mineral springs of Canada in two parts part II. the chemical character of some Canadian mineral springs

1918 ◽  
Author(s):  
R T Elworthy
Keyword(s):  
Mineral Springs ◽  
Chemical Character

Synthesis and properties of oxytocin analogues acting as irreversible inhibitors of the uterotonic response to oxytocin

1979 ◽  
Vol 44 (8) ◽  
pp. 2573-2582 ◽  
Author(s):  
Michal Lebl ◽  
Vera Bojanovska ◽  
Tomislav Barth ◽  
Karel Jošt
Keyword(s):  
Glutamic Acid ◽  
Active Esters ◽  
Irreversible Inhibitors ◽  
Reactive Groups ◽  
Chemical Character

A series of compounds containing reactive groups of different chemical character was synthetized from [4-glutamic acid]deamino-1-carba-oxytocin or from [2-O-methyltyrosine, 4-glutamic acid]deamino-1-carba-oxytocin. The analogues acted as specific irreversible inhibitors of the uterotonic response to oxytocin. Active esters of the initial compounds were the most effective inhibitors.

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