Obstructive Sleep Apnea as a Complication of Bipolar Disorder and Its Treatment: A Review and Approach to Management

2017 ◽  
Vol 19 (6) ◽  
Author(s):  
Surinder S. Moonga ◽  
David Mischoulon ◽  
John W. Winkelman ◽  
Theodore A. Stern
Keyword(s):  
Bipolar Disorder ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep

scholarly journals Risk of obstructive sleep apnea in patients with bipolar disorder: A nationwide population‐based cohort study in Taiwan

2018 ◽  
Vol 73 (4) ◽  
pp. 163-168
Author(s):  
En‐Ting Chang ◽  
Shih‐Fen Chen ◽  
Jen‐Huai Chiang ◽  
Ling‐Yi Wang ◽  
Chung‐Y Hsu ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Obstructive Sleep Apnea ◽  
Cohort Study ◽  
Sleep Apnea ◽  
Population Based ◽  
Obstructive Sleep

760 Does Obstructive Sleep Apnea Increase Suicidality in Patients with Bipolar Disorder?

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A296-A296
Author(s):  
Abhishek Reddy ◽  
Zeeshan Mansuri ◽  
Chintan Trivedi ◽  
Ramu Vadukapuram
Keyword(s):  
Bipolar Disorder ◽  
Obstructive Sleep Apnea ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Sleep Apnea ◽  
Suicidal Ideation ◽  
Logistic Regression Analysis ◽  
Primary Diagnosis ◽  
Adult Patients ◽  
Obstructive Sleep

Abstract Introduction Bipolar disorder (BPD) is associated with suicidality in adult population. There are several risk factors for suicide, however the relationship between Obstructive Sleep Apnea (OSA) and suicidality in patients with BPD has not been explored. Hence, we decided to perform this study with primary objective of comparison of suicidality by OSA diagnosis in patients with BPD. Methods We used inpatient hospitalization data from National Inpatient sample dataset year 2016–2018. Our primary population (BPD + OSA) was composed of adult patients admitted to the hospital with the primary diagnosis of Bipolar Disorder and secondary diagnosis of Obstructive sleep apnea. Age-gender matched (1:4 matching) control population was selected with primary diagnosis of BPD having no OSA (BPD-OSA). Data on suicidality (suicidal ideation/attempt) were collected and compared between the groups using logistic regression analysis methods by including OSA, age, gender, race, substance use disorder and personality disorder as predictors. Results From the dataset, 17895 patients were obtained for the BPD + OSA group (average age: 50.5 years, male 45.5%). After 1:4 age-gender matching, 71575 patients were included in the BPD-OSA group. In the unadjusted analysis, suicidal ideation was significantly high BPD+OSA group compared the BPD-OSA group (38.4% vs. 31.9%, p < 0.001). Rate of suicide attempt and self-inflicted injuries were similar in two groups (3.5% vs. 3.3%, p: 0.27). In the adjusted logistic regression analysis odds of suicidality were 36% more in BPD+OSA group compared to BPD-OSA (Odds Ratio: 1.36, 95% Confidence interval: 1.25–1.48, p < 0.001). Conclusion In adult patients with BPD, diagnosis of OSA significantly increases the odds of suicidality. Addressing OSA in patients with BPD, can improve management, and potentially reduce the incidence of suicide. We believe our study will be helpful in guiding future research and development on this issue. Support (if any) None

scholarly journals OBSTRUCTIVE SLEEP APNEA, CPAP AND BIPOLAR DISORDER – IS THERE A COMMON LINK?

2019 ◽  
Author(s):  
Daniel Esteves-Sousa ◽  
João Facucho-Oliveira ◽  
Margarida Albuquerque ◽  
Pedro Espada Dos Santos ◽  
Miguel Silva Costa ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep

Treating Velopharyngeal Inadequacy Using Bilateral Buccal Flap Revision Palatoplasty

2019 ◽  
Vol 4 (5) ◽  
pp. 878-892
Author(s):  
Joseph A. Napoli ◽  
Linda D. Vallino
Keyword(s):  
Systematic Review ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
A Priori ◽  
Sufficient Evidence ◽  
Obstructive Sleep ◽  
Before And After ◽  
Buccal Flap

Purpose The 2 most commonly used operations to treat velopharyngeal inadequacy (VPI) are superiorly based pharyngeal flap and sphincter pharyngoplasty, both of which may result in hyponasal speech and airway obstruction. The purpose of this article is to (a) describe the bilateral buccal flap revision palatoplasty (BBFRP) as an alternative technique to manage VPI while minimizing these risks and (b) conduct a systematic review of the evidence of BBFRP on speech and other clinical outcomes. A report comparing the speech of a child with hypernasality before and after BBFRP is presented. Method A review of databases was conducted for studies of buccal flaps to treat VPI. Using the principles of a systematic review, the articles were read, and data were abstracted for study characteristics that were developed a priori. With respect to the case report, speech and instrumental data from a child with repaired cleft lip and palate and hypernasal speech were collected and analyzed before and after surgery. Results Eight articles were included in the analysis. The results were positive, and the evidence is in favor of BBFRP in improving velopharyngeal function, while minimizing the risk of hyponasal speech and obstructive sleep apnea. Before surgery, the child's speech was characterized by moderate hypernasality, and after surgery, it was judged to be within normal limits. Conclusion Based on clinical experience and results from the systematic review, there is sufficient evidence that the buccal flap is effective in improving resonance and minimizing obstructive sleep apnea. We recommend BBFRP as another approach in selected patients to manage VPI. Supplemental Material https://doi.org/10.23641/asha.9919352

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