Plasma Insulin Level Correlation to Metabolic Parameter Shifts in Hospitalized Psychiatric Patients

2017 ◽  
Vol 19 (02) ◽  
Author(s):  
Andrew C. Naglich ◽  
Leigh Anne Nelson ◽  
Courtney A. Iuppa ◽  
Lauren A. Diefenderfer ◽  
Ellie S. R. Elliott ◽  
...  
Keyword(s):  
Plasma Insulin ◽  
Psychiatric Patients ◽  
Insulin Level ◽  
Plasma Insulin Level ◽  
Metabolic Parameter

scholarly journals Effect of clonidine on plasma insulin level in mice. Polia pharmacol

1978 ◽  
Vol 74 (3) ◽  
pp. 383-388
Author(s):  
Hikaru OZAWA ◽  
Masayoshi GOTO ◽  
Michiko TAKAHASHI ◽  
Toshio UEMATSU
Keyword(s):  
Plasma Insulin ◽  
Insulin Level ◽  
Plasma Insulin Level

Hepatic steatosis and the elevated plasma insulin level in patients with endogenous hypertriglyceridemia

Metabolism ◽  
1975 ◽  
Vol 24 (5) ◽  
pp. 653-664 ◽  
Author(s):  
Yoshisuke Maruhama ◽  
Akira Ohneda ◽  
Hiroshi Tadaki ◽  
Masao Ohtsuki ◽  
Akira Yanbe ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
Plasma Insulin ◽  
Insulin Level ◽  
Plasma Insulin Level ◽  
Elevated Plasma ◽  
Endogenous Hypertriglyceridemia

Disappearance of insulin in man: variation with the plasma insulin level

1981 ◽  
Vol 97 (3) ◽  
pp. 391-397 ◽  
Author(s):  
Karl-Göran Tranberg ◽  
Per Hagander ◽  
Jan Thorell
Keyword(s):  
Clearance Rate ◽  
Pancreatic Secretion ◽  
Plasma Insulin ◽  
Insulin Level ◽  
Glucose Infusion ◽  
Plasma Insulin Level ◽  
Exogenous Insulin ◽  
Fasting State ◽  
Endogenous Insulin ◽  
Arterial Blood

Abstract. Clearance rates of unlabelled insulin were studied in 45 unanaesthetized non-diabetic humans. The clearance rate, as well as the pancreatic secretion rate, of endogenous insulin was estimated from steady-state concentrations in portal and arterial blood. The clearance rate of exogenous insulin was determined after brief intraportal infusion. In the basal fasting state, the endogenous plasma insulin level varied as closely with the clearance of endogenous insulin as with the rate of pancreatic secretion. During elevation of insulin by glucose infusion, it varied predominantly with the rate of insulin secretion. Clearance of exogenous insulin did not vary with the pre-test endogenous insulin level. The clearance of endogenous insulin increased from 11 ml · min−1 · kg−1 in the basal fasting state to 17 ml · min−1 · kg−1 during glucose infusion. Clearance of exogenous insulin fell progressively with increasing dose, from 35 (8 mU/kg) to 14 (43 mU/kg) ml · min−1 · kg−1 at normoglycaemia and from 23 (8 mU/kg) to 17 (34 mU/kg) ml · min−1 · kg−1 at hyperglycaemia. The clearance of endogenous insulin was lower than that of exogenous insulin at normoglycaemia, but of similar size during glucose infusion. It is concluded that variation in clearance rate is partly responsible for variation in plasma insulin concentration, particularly in the basal fasting state, and that the clearance rate is lower in the basal state than otherwise. To some extent, the low clearance values for endogenous insulin in the basal state may reflect poor specificity of the insulin radioimmunoassay.

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