Is DSM-IV Bereavement Exclusion for Major Depressive Episode Relevant to Severity and Pattern of Symptoms?

2009 ◽  
Vol 70 (8) ◽  
pp. 1091-1097 ◽  
Author(s):  
Emmanuelle Corruble ◽  
Virginie-Anne Chouinard ◽  
Alexia Letierce ◽  
Philip A. P. M. Gorwood ◽  
Guy Chouinard
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Major Depressive ◽  
Dsm Iv

Empirical Investigation of Two Assumptions in the Diagnosis of DSM-IV Major Depressive Episode

2007 ◽  
Vol 41 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Chika Sakashita ◽  
Tim Slade ◽  
Gavin Andrews
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Sleep Problems ◽  
Composite International Diagnostic Interview ◽  
Population Based ◽  
Diagnostic Interview ◽  
Major Depressive ◽  
Diagnostic Threshold ◽  
Dsm Iv ◽  
The Relationship

Objective: The aim of the current study was to examine two major assumptions behind the DSM-IV diagnosis of major depressive episode (MDE): that depression represents a distinct category defined by a valid symptom threshold, and that each depressive symptom contributes equally to the diagnosis. Methods: Data were from the Australian National Survey of Mental Health and Wellbeing. Participants consisted of a random population-based sample of 10 641 community volunteers, representing a response rate of 78%. DSM-IV diagnoses of MDE and other mental disorders were obtained using the Composite International Diagnostic Interview, version 2.0. Analyses were carried out on the subsample of respondents who endorsed either depressed mood or loss of interest (n =2137). Multivariate linear regression analyses examined the relationship between the number and type of symptoms and four independent measures of impairment. Results: The relationship between the number of depressive symptoms and the four measures of impairment was purely linear. Three individual symptoms (sleep problems, energy loss, and psychomotor disturbance) were all independent predictors of three of the four measures of impairment. Conclusions: Counting symptoms alone is limited in guiding a clear diagnostic threshold. The differential impact of individual symptoms on impairment suggests that impairment levels may be more accurately estimated by weighting the particular symptoms endorsed.

Mean Beck Depression Inventory–II Scores by Severity of Major Depressive Episode

2001 ◽  
Vol 88 (3_suppl) ◽  
pp. 1075-1076 ◽  
Author(s):  
Robert A. Steer ◽  
Gregory K. Brown ◽  
Aaron T. Beck ◽  
William C. Sanderson
Keyword(s):  
Beck Depression Inventory ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Major Depressive ◽  
Dsm Iv ◽  
The Mean

The Beck Depression Inventory–II total scores of 35 (14%) outpatients who were diagnosed with a mild DSM–IV Major Depressive Episode (MDE), 144 (55%) outpatients with a moderate MDE, and 81 (31%) outpatients with a severe MDE were compared. The mean BDI–II total scores were, respectively, 18 ( SD = 8, 99% CI 12–23), 27 ( SD = 10, 99% CI 24–29), and 34 ( SD = 10, 99% CI 30–37) ( F2,257 = 33.25, p < .001). The mean BDI–II total score of the outpatients with a severe specifier was significantly higher than the mean BDI–II total score of the outpatients with a moderate specifier which was, in turn, significantly higher than the mean BDI–II total score of the outpatients with a mild specifier.

Suicide behavior and subthreshold psychiatric disorders among children and adolescents

2011 ◽  
Vol 26 (S2) ◽  
pp. 265-265
Author(s):  
J. Balazs ◽  
G. Dallos ◽  
A. Kereszteny ◽  
J. Gadoros
Keyword(s):  
Psychiatric Disorders ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Hospitalized Children ◽  
Major Depressive ◽  
Psychiatric Illnesses ◽  
Suicide Behavior ◽  
Child Psychiatric ◽  
Report Data ◽  
Dsm Iv

ObjectiveSuicide among adults have been associated to subthreshold psychiatric illnesses as well; however it is little known about the role of subthreshold mental disorders in suicide risk among children/adolescents.MethodsUsing the Mini International Neuropsychiatric Interview Kid the authors examined 105 hospitalized children/adolescents in the Vadaskert Child Psychiatric Hospital, Budapest. Current suicide behavior was defined as giving positive answer to any of the following questions: “In the past month did you: think you would be better off dead or wish you were dead? want to hurt yourself? think about killing yourself? attempt suicide?”ResultsWe report data on 105 hospitalized children/adolescents, 76 (72.4%) boys and 29 (27.6%) girls. The mean age of the subjects was 11.4 years (SD = 3.43, min: 5, max: 17). Current suicide behavior was present in 18 cases (17.1%). There were one person with current suicide behavior, who did not have any current DSM-IV disorder, but he/she had current subthreshold disorder. The majority (n = 16, 88.8%) of the children/adolescents with suicide behavior had both current subthreshold and DSM-IV disorders. Eight children/adolescents (44.4%) with current suicide behavior had current DSM-IV major depressive episode and further 5 children/adolescents (27,8%) had current subthreshold major depressive episode. The prevalence of DSM-IV and subthreshold major depressive episode was significantly higher among hospitalized children with suicide behavior (n = 18), than among hospitalized children without suicide behavior (n = 87) (X2 = 5,272, df = 1. p = 0,022).ConclusionsSubthreshold forms of pediatric psychiatric disorders need to be taken into account as well in suicide prevention.

Augmentation of Zonisamide in Poor or Non-responder Patients Treated with Duloxetine for Single or Recurrent Unipolar Major Depressive Episode

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
M. Fornaro ◽  
F. Bandini ◽  
C. Mattei ◽  
F. Battaglia ◽  
C. Ogliastro ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Wave Amplitude ◽  
Rating Scales ◽  
Major Depressive Episode ◽  
Open Label ◽  
Major Depressive ◽  
Open Label Study ◽  
Wide Range ◽  
Axis I ◽  
Dsm Iv

Objectives:The aim of our ongoing study is to investigate the effectiveness of Zonisamide augmentation to Duloxetine in partial and non-responder patients in course of Unipolar Major Depressive Episode.Method:35 outpatients will be enrolled in a 12-weeks open-label study including both genders, 18 to 65 years old subjects. Unipolar Major Depressive Episode diagnosis will be performed at screening time using “Structured Clinical Interview for DSM-IV-Axis-I Disorders- Italian 1996 version” (SCID-I, First et al., 1996) and by a ≥14 total score for the “Quick Inventory of Depressive Symptomathology-Self Rated” (QIDS-SR, Rush et al., 2003). Patients will be repeatedly evaluated during the course of the study using a wide range of mood and anxiety rating scales and monitoring biomarkers such as electroretinogram b-wave amplitude, interleukins, flogosis and BDNF factors etc. At week 6, Duloxetine partial/non responders will be augmetated to Zonisamide and further evaluations of mentioned markers will be repeated. A “Fisher-test” or χ² analysis will be performed at the end of the study. Expected p will be ≤ 0,005.Hypothesis:We expect Zonisamide augmentation to be an effective treatment for SNRI-resistant Major Depression.

scholarly journals Cross-national epidemiology of DSM-IV major depressive episode

BMC Medicine ◽  
2011 ◽  
Vol 9 (1) ◽  
Author(s):  
Evelyn Bromet ◽  
Laura Helena Andrade ◽  
Irving Hwang ◽  
Nancy A Sampson ◽  
Jordi Alonso ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Major Depressive ◽  
Dsm Iv ◽  
Cross National

Detection and Prevalence of Depressive Disorders in Primary Care Settings in Hungary

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
P. Torzsa ◽  
X. Gonda ◽  
N. Szokontor ◽  
B. Sebestyen ◽  
G. Faludi ◽  
...  
Keyword(s):  
Primary Care ◽  
Beck Depression Inventory ◽  
Depressive Episode ◽  
Depressive Disorders ◽  
Major Depressive Episode ◽  
Care Service ◽  
Health Care Service ◽  
Major Depressive ◽  
Current Prevalence ◽  
Dsm Iv

Background:Although depressive disorders are common conditions in primary health care service, and many depressed patients consult their general practitioners, GPs have some difficulties in the detection and correct diagnosis of depression. Unrecognized and untreated depression causes great health and economic burden and also contributes to significant suffering, therefore the correct recognition of affective disorder in GP settings is an important healthcare target. The aim of our study was to assess the prevalence of depressive disorders in general practices in Hungary and also to assess the sensitivity and specificity of different depression screening instruments.Method:In the present study the current prevalence of DSM-IV depressive disorders were surveyed among 984 primary care attendees in 6 GP practices in Hungary, using the Beck Depression Inventory and the PRIME-MD screening instrument.Results:The current prevalence rate of any PRIME-MD DSM-IV depressive disorders, including symptomatic major depressive episode, were 18.5% and 7.3% respectively. Beck Depression Inventory identified any current depressive disorders with 95% sensitivity and 56% specificity and the same figures for current symptomatic major depressive episode were 83% and 23%, respectively.Discussion:Our results are similar to those reported previously from Hungary and from other countries. The findings also indicate that the Beck Depression Inventory and PRIME-MD can help in detecting depressive disorders in primary care.

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