scholarly journals FACTORS INFLUENCING ADHERENCE TO IMATINIB IN INDIAN CHRONIC MYELOID LEUKEMIA PATIENTS: A CROSS-SECTIONAL STUDY

2015 ◽  
Vol 7 ◽  
pp. e2015013 ◽  
Author(s):  
Jyotsna Kapoor ◽  
Narendra Agrawal ◽  
Rayaz Ahmad ◽  
Sanjeev Kumar Sharma ◽  
Anshul Gupta ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Monthly Income ◽  
Concomitant Drug ◽  
Factors Influencing ◽  
Adherence Behaviour ◽  
Prevalence Of Depression ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale

Adherence to imatinib(IM) is of utmost importance in patients with chronic myeloid leukemia(CML) to maximise treatment effectiveness. The main objective is to measure adherence to    IM & to evaluate individual patient characteristics, personal, treatment related &                    psychological factors influencing adherence behaviour. Hundred patients  receiving IM were analysed for adherence behaviour using 9 item Morisky Medication Adherence Scale              (9-MMAS) . Various factors were assessed for their impact on adherence behaviour.  These   factors were age, gender, duration of treatment, frequency & dosing of treatment, use  of        tobacco & alcohol, educational qualification,employment status,monthly  income, side effects, financial assistance in treatment, social support, knowledge about medicine & disease,         concomitant drug burden, polypharmacy, physician patient interaction, patient  educational    sessions & prevalence of depression. Seventy five percent of patients were found to be           adherent. On univariate analysis, prevalence of depression (p<0.000001), moderate severe     depression (p<0.000001), concomitant drug burden (p=0.036) & monthly income (p=0.015) were found to be significantly influencing adherence. The final multivariate model retained   prevalence of depression with OR= 10.367  (95% CI, 3.112- 34.538) as independent predictor of adherence to therapy. This study suggests that identification & treatment of depression among CML patients may further enhance adherence to IM therapy.Keywords: Chronic Myeloid Leukemia, Adherence, Imatinib, Nine Item Morisky Medication Adherence Scale, Patient Health Questionnaire -9.

scholarly journals The 8-item Morisky medication adherence scale: validation of a Portuguese version in HIV patients

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A Aguiar ◽  
C Piñeiro ◽  
R Serrão ◽  
R Duarte
Keyword(s):  
Medication Adherence ◽  
Psychometric Properties ◽  
Reliability Analysis ◽  
Cronbach’S Alpha ◽  
Portuguese Version ◽  
Cronbach's Alpha ◽  
Adherence To Medication ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale ◽  
The Mean

Abstract Background Antiretroviral therapy (ART) has the most effective treatment for people with HIV, but its effectiveness depends on the individual medication adherence. Morisky Medication Adherence Scale (MMAS-8) is one of the most widely used scales to assess patient adherence. Thus, we aimed to validate a Portuguese version of MMAS-8 and determine its psychometric properties in HIV positive patients. Methods A cross-sectional survey was conducted in Centro Hospitalar Universitário São João (Porto, northern Portugal) at the infectious diseases department. After authorization to use the scale - granted by the author - and, a standard forward-backwards procedure to translate MMAS-8 to Portuguese, the questionnaire was applied to 233 patients with HIV doing ART. Reliability was assessed using Cronbach's alpha and test-retest reliability. Three levels of adherence were considered: 0 to &lt; 6 (low), 6 to &lt; 8 (medium), 8 (high). Results In the studied sample, the mean age was 45.03 years (SD = 11.63), 80.3% men, 19.3% women and 1 transgender, and 53.8% had ≤9 years of education. The mean number of prescribed ART per patient was 1.76. The mean score for the medication adherence scale was 7.29 (SD = 6.74). For the reliability analysis, 12 patients were excluded due to missing data (n = 221). Regarding the level of adherence, 22.5% were low adhering, 71.6% medium and 5.9% high. Corrected item-total correlations showed that 1 item does not correlate very well with the overall scale and was dropped. Scale reliability analysis for the remaining 7 items revealed an overall Cronbach's alpha of 0.661. Women had a protective effect on adherence (OR = 0.31;95%CI:0.15-0.66). Number of years doing ART, age of participants, and type of residence didn't show to be correlated with adherence. Conclusions MMAS-8 is a reliable and valid measure to detect patients at risk of non-adherence. A satisfactory Cronbach's alfa (0.661) was obtained. In general, adherence to medication was medium or high. Key messages This scale can be applied nationwide in other different hospitals, as it could serve as a tool for measuring adherence to ART that can allow for better health care to the ones that are low adhering. A Portuguese version of the MMAS-8 was created for measuring adherence to ART that maintained a similar structure to the original MMAS-8 and good psychometric properties.

scholarly journals Validation of the French Translated Version of the Osteoporosis Specific Morisky Medication Adherence Scale (OS-MMAS) in France

2013 ◽  
Vol 16 (7) ◽  
pp. A568 ◽  
Author(s):  
M. Feudjo Tepie ◽  
C. Kempf ◽  
A. Letierce ◽  
I. Ferreira ◽  
L. Kalouche-Khalil ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale

scholarly journals Determinants of Medication Adherence to Antihypertensive Medications among a Chinese Population Using Morisky Medication Adherence Scale

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e62775 ◽  
Author(s):  
Gabrielle K. Y. Lee ◽  
Harry H. X. Wang ◽  
Kirin Q. L. Liu ◽  
Yu Cheung ◽  
Donald E. Morisky ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Chinese Population ◽  
Antihypertensive Medications ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale

scholarly journals ASSESSMENT & EVALUATION ON THE KNOWLEDGE, ATTITUDE & PRACTICE TOWARDS MEDICATION THERAPY MANAGEMENT AMONG COMMUNITY OF DAVANGERE CITY

2017 ◽  
Vol 10 (4) ◽  
pp. 380
Author(s):  
Gloria K Sam ◽  
Jobin Thomas ◽  
Riya Alexander ◽  
Sheen Ann Varughese
Keyword(s):  
Medication Adherence ◽  
Lifestyle Modification ◽  
Medication Therapy Management ◽  
Patient Counseling ◽  
Therapy Management ◽  
Medication Therapy ◽  
Attitude And Practice ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale ◽  
Knowledge Attitude And Practice

Objectives: The prime objective of this study is to assess knowledge, attitude, and practice (KAP) toward medications in a community of Davangere city.Methods: This community-based study was conducted for 6 months using medication therapy management aspects. Ethical clearance was obtainedfrom the Institutional Ethical Committee. Patients above 18 years of age who were willing to participate were included in the study. The data werecollected using specific data collection forms, and KAP toward medications of each patient was assessed using KAP questionnaire. Medicationadherence was analyzed using Morisky Medication Adherence Scale 4. Patient counseling about disease, medication, and lifestyle modification wasgiven, and the orally taking household drugs were segregated according to class and specific clinical uses.Results: Out of 129 patients, 58.1% were male. Out of 19 diseases encountered during the study, diabetes mellitus (32.56%) and hypertension(25.58%) were most prevalent. Majority of patients (63.57%) were prescribed with cardiovascular agents. Paracetamol was found as a commonhousehold drug. Sixty-nine percent of patients were procuring medication directly from the pharmacy and the remaining 31% were procuring theirmedication after consulting the physician. Mean scores of KAP in basal and endpoint assessment were compared using Student’s t-test. p value wasfound to be <0.000.Conclusion: The study tried to entitle the name of pharmacist as a patient educator who gives proper guidance to the patient and family membersabout the disease, domestic drug management, lifestyle modification, etc. The result of efficient patient counseling will be reflected on the properadherence of patient toward the medication and improved quality of life.Keywords: Knowledge, attitude and practice (KAP), Medication therapy management (MTM), Morisky medication adherence Scale – 4 (MMAS-4),patient education.

Morisky Medication Adherence Scale-8

2008 ◽  
Author(s):  
Donald Morisky ◽  
Alfonso Ang ◽  
Marie Krousel-Wood ◽  
Harry J. Ward
Keyword(s):  
Medication Adherence ◽  
Morisky Medication Adherence Scale ◽  
Adherence Scale ◽  
Scale 8
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