scholarly journals Measuring Aqueduct of Sylvius cerebrospinal fluid flow in multiple sclerosis using different software packages

2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Maria Marcella Laganà ◽  
Dejan Jakimovski ◽  
Niels Bergsland ◽  
Robert Zivadinov
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Cerebrospinal Fluid Flow ◽  
Software Packages ◽  
Aqueduct Of Sylvius

Not available

scholarly journals Measuring Aqueduct of Sylvius Cerebrospinal Fluid Flow in Multiple Sclerosis Using Different Software

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 325
Author(s):  
Maria Marcella Laganà ◽  
Dejan Jakimovski ◽  
Niels Bergsland ◽  
Michael G. Dwyer ◽  
Francesca Baglio ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Flow Rate ◽  
Software Package ◽  
Perfect Agreement ◽  
Cross Sectional ◽  
Cerebrospinal Fluid Flow ◽  
Software Packages ◽  
Aqueduct Of Sylvius

Aqueduct of Sylvius (AoS) cerebrospinal fluid flow can be quantified using phase-contrast (PC) Magnetic Resonance Imaging. The software used for AoS segmentation might affect the PC-derived measures. We analyzed AoS PC data of 30 people with multiple sclerosis and 19 normal controls using three software packages, and estimated cross-sectional area (CSA), average and highest AoS velocity (Vmean and Vmax), flow rate and volume. Our aims were to assess the repeatability and reproducibility of each PC-derived measure obtained with the various software packages, including in terms of group differentiation. All the variables had good repeatability, except the average Vmean, flow rate and volume obtained with one software package. Substantial to perfect agreement was seen when evaluating the overlap between the AoS segmentations obtained with different software packages. No variable was significantly different between software packages, with the exception of Vmean diastolic peak and CSA. Vmax diastolic peak differentiated groups, regardless of the software package. In conclusion, a clinical study should preliminarily evaluate the repeatability in order to interpret its findings. Vmax seemed to be a repeatable and reproducible measure, since the pixel with its value is usually located in the center of the AoS, and is thus unlikely be affected by ROI size.

Predictive Value of Cerebrospinal Fluid Flow Cytometry in Pediatric Multiple Sclerosis

2015 ◽  
Vol 46 (S 01) ◽  
Author(s):  
C. Elpers ◽  
C. Groß ◽  
J. Althaus ◽  
B. Fiedler ◽  
S. Meuth ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Flow Cytometry ◽  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Predictive Value ◽  
Cerebrospinal Fluid Flow ◽  
Pediatric Multiple Sclerosis

Venous and cerebrospinal fluid flow in multiple sclerosis: A case-control study

2010 ◽  
Vol 68 (2) ◽  
pp. 255-259 ◽  
Author(s):  
Peter Sundström ◽  
Anders Wåhlin ◽  
Khalid Ambarki ◽  
Richard Birgander ◽  
Anders Eklund ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Case Control Study ◽  
Case Control ◽  
Cerebrospinal Fluid Flow ◽  
Control Study

Computational investigation of subject-specific cerebrospinal fluid flow in the third ventricle and aqueduct of Sylvius

2007 ◽  
Vol 40 (6) ◽  
pp. 1235-1245 ◽  
Author(s):  
Vartan Kurtcuoglu ◽  
Michaela Soellinger ◽  
Paul Summers ◽  
Kevin Boomsma ◽  
Dimos Poulikakos ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Third Ventricle ◽  
Computational Investigation ◽  
Cerebrospinal Fluid Flow ◽  
The Third ◽  
Aqueduct Of Sylvius ◽  
Subject Specific

scholarly journals Dynamic 11C-PiB PET Shows Cerebrospinal Fluid Flow Alterations in Alzheimer Disease and Multiple Sclerosis

2019 ◽  
Vol 60 (10) ◽  
pp. 1452-1460 ◽  
Author(s):  
Julia J. Schubert ◽  
Mattia Veronese ◽  
Livia Marchitelli ◽  
Benedetta Bodini ◽  
Matteo Tonietto ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Alzheimer Disease ◽  
Cerebrospinal Fluid Flow
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