scholarly journals Effect of human mesenchymal stem cells on hepatoma cell line

2011 ◽  
Vol 1 (1) ◽  
pp. 12
Author(s):  
Mohamed T. Abdel Aziz ◽  
Hanan H. Fouad ◽  
Nagwa K. Roshdy ◽  
Laila A. Rashed ◽  
Dina Sabry ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cell Line ◽  
Hepatoma Cell ◽  
Human Mesenchymal Stem Cells ◽  
Hepatoma Cell Line

scholarly journals Effect of Mesenchymal Stem Cells and a Novel Curcumin Derivative on Notch1 Signaling in Hepatoma Cell Line

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Mohamed Talaat Abdel Aziz ◽  
Hussien Mostafa Khaled ◽  
Ali El Hindawi ◽  
Nagwa Kamal Roshdy ◽  
Laila A. Rashed ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cell Line ◽  
Hepg2 Cells ◽  
Target Genes ◽  
Hepatoma Cell ◽  
Hepatoma Cell Line ◽  
Notch1 Signaling ◽  
Notch1 Signaling Pathway ◽  
Curcumin Derivative

This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditioned medium (MSCs CM), HepG2 cells treated with a NCD, HepG2 cells treated with MSCs CM and NCD, and HepG2 cells treated with MSCs CM (CM of MSCs pretreated with a NCD). Expression of Notch1, Hes1, VEGF, and cyclin D1 was assessed by real-time, reverse transcription-polymerase chain reaction (RT-PCR) in HepG2 cells. In addition, HepG2 proliferation assay was performed in all groups. Notch1 and its target genes (Hes1 and cyclin D1) were downregulated in all treated groups with more suppressive effect in the groups treated with both MSCs and NCD. Also, treated HepG2 cells showed significant decrease in cell proliferation rate. These data suggest that modulation of Notch1 signaling pathway by MSCs and/or NCD can be considered as a therapeutic target in HCC.

Chemotactic Migration of Human Mesenchymal Stem Cells and MC3T3-E1 Osteoblast-Like Cells Induced by COS-7 Cell Line Expressing rhBMP-7

2006 ◽  
Vol 0 (0) ◽  
pp. 060706073730022
Author(s):  
Dong Hee Lee ◽  
Bong Joo Park ◽  
Min-Sub Lee ◽  
Jin Woo Lee ◽  
Jeong Koo Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cell Line ◽  
Human Mesenchymal Stem Cells ◽  
Chemotactic Migration

Human mesenchymal stem cells inhibit metastasis of a hepatocellular carcinoma model using the MHCC97-H cell line

2010 ◽  
Vol 101 (12) ◽  
pp. 2546-2553 ◽  
Author(s):  
Guo-Cai Li ◽  
Qing-Hai Ye ◽  
Yu-Hua Xue ◽  
Hai-Jing Sun ◽  
Hai-Jun Zhou ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cell Line ◽  
Human Mesenchymal Stem Cells

Chemotactic Migration of Human Mesenchymal Stem Cells and MC3T3-E1 Osteoblast-Like Cells Induced by COS-7 Cell Line Expressing rhBMP-7

2006 ◽  
Vol 12 (6) ◽  
pp. 1577-1586 ◽  
Author(s):  
Dong Hee Lee ◽  
Bong Joo Park ◽  
Min-Sub Lee ◽  
Jin Woo Lee ◽  
Jeong Koo Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cell Line ◽  
Human Mesenchymal Stem Cells ◽  
Chemotactic Migration

Proliferation and multi-differentiation potentials of human mesenchymal stem cells on thermoresponsive PDMS surfaces grafted with PNIPAAm

2010 ◽  
Vol 30 (6) ◽  
pp. 455-455 ◽  
Author(s):  
Dongyan Shi ◽  
Dan Ma ◽  
Feiqing Dong ◽  
Chen Zong ◽  
Liyue Liu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells
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