scholarly journals Primary mediastinal Castleman's disease

Rare Tumors ◽  
2010 ◽  
Vol 2 (1) ◽  
pp. 34-35 ◽  
Author(s):  
Mohamed A.H Regal ◽  
Yasser M Aljehani ◽  
Hanan Bousbait

Castleman's disease is a rare entity with an unknown etiology which was first described by Castleman in 1954. It is a lymphoproliferative disorder histologically classified into three types; hyaline-vascular, plasma cell type and mixed type. It might be localized or multicentric and usually involves the mediastinum. We report a case of Castleman's disease discovered accidentally in a case of blunt chest trauma which caused a challenging diagnostic process and management.

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Rafael Parra-Medina ◽  
José Ismael Guio ◽  
Patricia López-Correa

Castleman’s disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in the literature, and all have been reported in adults. Herein we describe the case of a 15-year-old female who presented with a slow-growing tumor in the right breast. The tumor was excised and histopathological examination demonstrated hyaline vascular variant CD. After two years of follow-up, the patient was asymptomatic without evidence of cervical or axillary lymphadenopathy.


2013 ◽  
Vol 97 (2) ◽  
pp. 275-279 ◽  
Author(s):  
Akihito Momoi ◽  
Masaru Kojima ◽  
Takeshi Sakai ◽  
Junya Ajiro ◽  
Noriatsu Isahai ◽  
...  

Pathobiology ◽  
2011 ◽  
Vol 78 (4) ◽  
pp. 227-232 ◽  
Author(s):  
Jeong-Hyeon Jo ◽  
Young-Soo Park ◽  
Yoon Kyung Jeon ◽  
Soo Jeong Nam ◽  
Jooryung Huh

2009 ◽  
Vol 2 ◽  
pp. CMBD.S2161 ◽  
Author(s):  
Ibrahiem Saeed Abdul-Rahman ◽  
Ali M. Al-Amri ◽  
Khalid Qassim Ghallab

Castleman's disease (CD) is a group of rare lymphoproliferative disorders sharing characteristic clinical and histological features, and usually accompanied by a marked systemic inflammatory response. Three histological patterns of lymph nodes were described: the hyaline-vascular, the plasma-cell and the mixed types. The former is more common (80%-90%) and tends to be localized. The plasma cell type is more aggressive and usually multicentric. It is interesting that the inflammatory manifestations seem to be related to a lymph node lesion, because the systemic symptoms and inflammatory activity can return to normal after surgical excision or successful medical treatment of the disease. We report here our 15-year experience with this rare disease in King Fahd Hospital of the University, Al-Khobar, Saudi Arabia, focusing on the clinical features, therapy, and patients'outcome.


2009 ◽  
Vol 19 (2) ◽  
pp. 220-224 ◽  
Author(s):  
Masaru Kojima ◽  
Naoya Nakamura ◽  
Tadashi Motoori ◽  
Ken Shimizu ◽  
Joji Haratake ◽  
...  

2003 ◽  
Vol 112 (9) ◽  
pp. 813-816 ◽  
Author(s):  
Daniel S. Samadi ◽  
Neil G. Hockstein ◽  
Lawrence W. C. Tom

Castleman's disease (CD) is a rare, benign lymphoepithelial disease of unknown cause that presents most commonly in the mediastinum. There are 2 histologic types of CD: the hyaline vascular type and the plasma cell type. In the head and neck, 98% of these lesions are of the hyaline vascular type. The differential diagnosis of CD includes reactive lymphadenopathy, lymphoproliferative disorders, lymph node metastasis, and other conditions. Approximately 80 cases of CD have been reported in children; head and neck involvement in children is extremely rare. A case of a child with intraparotid CD is presented; the clinical course, histopathologic presentation, radiographic findings, and management of CD are reviewed.


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