scholarly journals Multicentric reticulohistiocytosis: an example of the value of skin biopsy in joint disease

2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Ruth Smith ◽  
Chris Stonard ◽  
Rengi Mathew
Keyword(s):  
Skin Biopsy ◽  
Rare Condition ◽  
Joint Disease ◽  
Significant Morbidity ◽  
Multicentric Reticulohistiocytosis

We describe a case of multicentric reticulo-histiocytosis. It is a rare condition but one which causes significant morbidity to skin and joints. There is no consensus on treatment, but here we report a good response to infliximab. We also use the case to emphasise the value of skin biopsy in diagnosing rheumatological conditions.

scholarly journals Bilateral thalamus stroke due to percheron artery

2021 ◽  
Vol 32 (2) ◽  
pp. 193-195
Author(s):  
Zeferino Demartini Junior ◽  
Jennyfer Paulla Galdino Chaves ◽  
Roberto Lages ◽  
Diogo Cardoso ◽  
Luana Antunes Maranha Gatto ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Ischemic Stroke ◽  
Functional Recovery ◽  
Early Recognition ◽  
Rare Condition ◽  
Common Trunk ◽  
Significant Morbidity ◽  
Anatomical Variant ◽  
Cerebellar Artery ◽  
Bilateral Thalamus

Bilateral thalamus ischemic stroke is a rare condition that carries significant morbidity and mortality in comparison to other forms of stroke. It is usually associated with an anatomical variant with the thalamic paramedian arteries arising from a common trunk from the posterior cerebellar artery, known as Percheron artery. This infarct is difficult to be recognized and early recognition of this syndrome improves survival and functional recovery. We report a case of bilateral thalamic stroke after cardiac surgery.

scholarly journals Isolated penile Fournier’s: a caveat

2021 ◽  
Vol 8 (10) ◽  
pp. 3197
Author(s):  
Theakarajan Rajendran ◽  
Rajapriyan Paneerselvam ◽  
Shikhar Verma ◽  
Balasubramanian Gopal
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Rare Condition ◽  
Significant Morbidity ◽  
Split Skin Graft ◽  
Elderly Male ◽  
Mortality And Morbidity ◽  
Split Skin

Isolated penile Fournier’s gangrene is a rare condition causing significant morbidity to the patients. It occurs due to urinary tract infection or trauma. We describe an elderly male who presented with blackish discoloration of the skin of the penis with fever. Examination revealed a necrotic patch over the shaft of the penis without any other foci of infection around the perineum. Penis was debrided, and the antibiogram showed Escherichia coli sensitive to amikacin. He received seven days of antibiotics, and the wound granulated well. A split skin graft was used to cover the wound to prevent contraction. This unusual presentation requires expeditious management to prevent mortality and morbidity.

scholarly journals Scleroderma with Acro-Osteolysis and Papular Mucinosis Resembling Multicentric Reticulohistiocytosis

2020 ◽  
Author(s):  
João Dantas ◽  
Isabela S de Oliveira ◽  
Emanuela P Fonseca ◽  
Mittermayer Barreto Santiago
Keyword(s):  
Differential Diagnosis ◽  
Systemic Sclerosis ◽  
Bone Resorption ◽  
Physical Examination ◽  
Skin Biopsy ◽  
Laboratory Tests ◽  
Skin Lesions ◽  
Imaging Studies ◽  
Plain Radiographs ◽  
Multicentric Reticulohistiocytosis

Objectives: We describe a case of systemic sclerosis (SS) with acro-osteolysis associated with cutaneous mucinosis, usually characterized by mucin deposition in the skin. The main differential diagnosis was multicentric reticulohistiocytosis due to the presentation of papulonodular skin lesions. Materials and methods: A physical examination, imaging studies and laboratory tests were performed. Results: Distal bone resorption was evident on plain radiographs, and skin biopsy confirmed mucinosis. The SS diagnosis was based on the clinical features, high levels of antinucleolar antibodies and typical nailfold capillaroscopy findings. Conclusion: To the best of our knowledge, this is the first description of cutaneous mucinosis accompanying SS with acro-osteolysis.

scholarly journals A rare case of necrotizing fasciitis of eyelid in a young immunocompetent lady- case report and review of literature

2021 ◽  
Vol 7 (11) ◽  
pp. 1834
Author(s):  
Nithya Venkataramani ◽  
Sonali Muralidhar ◽  
Ravi Sachidananda
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Early Identification ◽  
Rare Case ◽  
Rare Condition ◽  
Necrotising Fasciitis ◽  
Aggressive Treatment ◽  
Review Of Literature ◽  
Significant Morbidity ◽  
Rapid Spread

<p class="abstract">Necrotising fasciitis of the periorbital region is a rare condition where there is destruction of the periorbital soft tissue with potential of rapid spread causing significant morbidity and mortality. It is generally seen in immuno suppressed individuals following trivial trauma. Here we present a case of periorbital necrotising fasciitis in a young immonocompetent lady with emphasis on early identification and aggressive treatment to prevent loss of vision and mortality.</p>

scholarly journals Boerhaave’s Syndrome: A Review of the Initial Management with Illustrative Case History

2007 ◽  
Vol 6 (2) ◽  
pp. 60-64
Author(s):  
Khai Ping Ng ◽  
◽  
Sue Brauer ◽  
J Snape ◽  
◽  
...  
Keyword(s):  
High Mortality ◽  
Case History ◽  
Rare Condition ◽  
Recent Case ◽  
Illustrative Case ◽  
Boerhaave’S Syndrome ◽  
Significant Morbidity ◽  
Initial Management ◽  
Front Door ◽  
Boerhaave's Syndrome

Boerhaave’s syndrome is a rare condition on the acute medical ‘take’ but has a high mortality and significant morbidity if not diagnosed early. This article reviews the approach to management at the ‘front door’, summarising the initial investigations and treatment. A recent case presenting to our unit is included at the end of the review to illustrate some of the issues raised.

scholarly journals Severe gastroparesis after orthotopic heart transplantation

2020 ◽  
Author(s):  
Philipp Angleitner ◽  
Michael A Arnoldner ◽  
Andreas O Zuckermann ◽  
Arezu Z Aliabadi-Zuckermann
Keyword(s):  
Gastric Emptying ◽  
Side Effects ◽  
Heart Transplantation ◽  
Therapeutic Strategy ◽  
Rare Condition ◽  
Orthotopic Heart Transplantation ◽  
Significant Morbidity ◽  
Immunosuppressive Medication ◽  
Increased Risk

Abstract We present a case of severe gastroparesis in a recipient of orthotopic heart transplantation. Although a rare condition after heart transplantation, it is a potential cause of significant morbidity, including vomiting, aspiration and pneumonia. Moreover, impaired gastric emptying alters the pharmacokinetics of immunosuppressive medication with increased risk of severe side effects. Herein, we describe a diagnostic and therapeutic strategy that was successfully applied in a patient with gastroparesis.

scholarly journals Juvenile Localized Scleroderma: A Very Rare Case

2015 ◽  
Vol 3 (2) ◽  
pp. 96-101
Author(s):  
Nibedita Paul ◽  
Md Rafiqul Islam ◽  
Nadia Nusrat ◽  
Lazina Sharmin ◽  
Md Mahamudul Hasan
Keyword(s):  
Early Diagnosis ◽  
Skin Biopsy ◽  
Rare Case ◽  
Flexion Contracture ◽  
Localized Scleroderma ◽  
Significant Morbidity ◽  
Medical College ◽  
Psychological Disabilities ◽  
Juvenile Localized Scleroderma ◽  
Little Finger

Juvenile localized scleroderma (JLS) is a rare chronic inflammatory and fibrosing disorder. It can result in significant morbidity, disfigurement, and severe functional, aesthetic and psychological disabilities. Patients with JLS should be identified early, evaluated extensively, treated aggressively, and monitored carefully. Here the case of a 2 year old boy is reported who was admitted into the department of Paediatrics of Delta Medical College & Hospital, Dhaka, Bangladesh with painful swelling of all fingers of both hands for 6 months and blackish patches over the fingers for the last one and half months. Left little finger was the first finger affected and there was flexion contracture of both left little and index fingers. The boy was diagnosed as a case of juvenile localized scleroderma and was confirmed by skin biopsy. We treated the child with methotrexate and prednisolone. It is very essential to raise awareness about this disease among clinicians and also parents for early diagnosis and treatment.Delta Med Col J. Jul 2015; 3(2): 96-101

Update in Pediatric Pseudotumor Cerebri Syndrome

2020 ◽  
Vol 40 (03) ◽  
pp. 286-293
Author(s):  
Shannon J. Beres
Keyword(s):  
Surgical Treatment ◽  
Intracranial Hypertension ◽  
Pediatric Population ◽  
Age Groups ◽  
Rare Condition ◽  
Pseudotumor Cerebri ◽  
Significant Morbidity ◽  
Increased Intracranial Pressure ◽  
Pseudotumor Cerebri Syndrome ◽  
Eye Exams

AbstractPseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as idiopathic intracranial hypertension or primary intracranial hypertension, or can be secondary to medications and associated medical conditions. Given the threat to vision, early detection and treatment is needed in all age groups. However, identifying papilledema or pseudopapilledema in children presents unique challenges sometimes as a result of differences between prepubertal and postpubertal children, further elucidating the complex pathophysiology. Management requires brain imaging, lumbar puncture, and frequent eye exams with medical and rarely surgical treatment. Visual outcomes in children are favorable if caught early and management can be prolonged over years. Pediatric PTCS is different from adult PTCS in many ways, and this review will focus on the most updated definitions of the disease, theories of pathophysiology, management, and treatment in the pediatric population.

Apportionment of Impairment from Meniscal Tears and Knee Arthritis

2013 ◽  
Vol 18 (5) ◽  
pp. 1-10 ◽  
Author(s):  
Charles N. Brooks ◽  
James B. Talmage
Keyword(s):  
Medial Meniscus ◽  
Degenerative Joint Disease ◽  
Joint Disease ◽  
Detailed Knowledge ◽  
Meniscal Tears ◽  
Knee Arthritis ◽  
Degenerative Arthritis ◽  
Study Results ◽  
Physical Findings ◽  
Causation Analysis

Abstract Meniscal tears and osteoarthritis (osteoarthrosis, degenerative arthritis, or degenerative joint disease) are two of the most common conditions involving the knee. This article includes definitions of apportionment and causes; presents a case report of initial and recurrent tears of the medial meniscus plus osteoarthritis (OA) in the medial compartment of the knee; and addresses questions regarding apportionment. The authors, experienced impairment raters who are knowledgeable regarding the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), show that, when instructions on impairment rating are incomplete, unclear, or inconsistent, interrater reliability diminishes (different physicians may derive different impairment estimates). Accurate apportionment of impairment is a demanding task that requires detailed knowledge of causation for the conditions in question; the mechanisms of injury or extent of exposures; prior and current symptoms, functional status, physical findings, and clinical study results; and use of the appropriate edition of the AMA Guides. Sometimes the available data are incomplete, requiring the rating physician to make assumptions. However, if those assumptions are reasonable and consistent with the medical literature and facts of the case, if the causation analysis is plausible, and if the examiner follows impairment rating instructions in the AMA Guides (or at least uses a rational and hence defensible method when instructions are suboptimal), the resulting apportionment should be credible.

Current evidence and prospects for medical treatment of abdominal aortic aneurysms

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 217-223 ◽  
Author(s):  
Diehm ◽  
Schmidli ◽  
Dai-Do ◽  
Baumgartner
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Medical Treatment ◽  
Endovascular Treatment ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Current Evidence ◽  
Significant Morbidity ◽  
Abdominal Aortic ◽  
Risk Of Rupture

Abdominal aortic aneurysm (AAA) is a potentially fatal condition with risk of rupture increasing as maximum AAA diameter increases. It is agreed upon that open surgical or endovascular treatment is indicated if maximum AAA diameter exceeds 5 to 5.5cm. Continuing aneurysmal degeneration of aortoiliac arteries accounts for significant morbidity, especially in patients undergoing endovascular AAA repair. Purpose of this review is to give an overview of the current evidence of medical treatment of AAA and describe prospects of potential pharmacological approaches towards prevention of aneurysmal degeneration of small AAAs and to highlight possible adjunctive medical treatment approaches after open surgical or endovascular AAA therapy.

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