scholarly journals Reference values for ductus venosus doppler indices of normal gestation at 22-37 weeks: A Vietnamese cohort study

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Nguyen Thi Hong ◽  
Nguyen Minh Duc ◽  
Le Hoang ◽  
Phan Truong Duyet ◽  
Dang Hong Thien ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pulsatility Index ◽  
Fetal Heart ◽  
Heart Function ◽  
Ductus Venosus ◽  
Exclusion Criteria ◽  
Resistivity Index ◽  
Study Results ◽  
Doppler Indices ◽  
Normal Gestation

Prenatal doppler ultrasound of the ductus venosus plays an important role in the evaluation of fetal circulation and fetal heart function. We aimed to establish the percentile of Resistivity Index (RI) and Pulsatility Index (PI) of the Ductus Venosus (DV) among normal Vietnamese fetuses with a gestation from 22 to 37 weeks in a cohort study. Normal Vietnamese fetuses with a gestation ranging from 22 to 37 weeks were examined in a cohort study. The PI and RI were recorded from the DV. We analyzed 640 participants who all fulfilled the inclusion and exclusion criteria of our study. Results: There was a significant correlation between RI, PI and gestational age as shown with the equations y = 0.077x – 0.003x2 + 3.493e - 5x3 (r=0.97) and y = 0.106x – 0.004x2 + 4.5e - 5x3 (r=0.94), respectively. A centile module was constructed for the DV RI and PI indices among normal Vietnamese fetuses with gestation from 22 to 37 weeks.

scholarly journals Reference ranges Of Uterine Artery Doppler Indices (Pulsatility index and Resistivity index) in pregnant women of Eastern part of Uttar Pradesh INDIA

2021 ◽  
Author(s):  
Anjali Rani ◽  
Madhu Jain ◽  
RC Shukla ◽  
Ishan Ishan ◽  
TB Singh ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Pulsatility Index ◽  
Uterine Artery ◽  
Reference Range ◽  
Color Doppler ◽  
Reference Ranges ◽  
Uterine Artery Doppler ◽  
Resistivity Index ◽  
Doppler Indices

Abstract ObjectivePreeclampsia and eclampsia are one of major cause of maternal mortality. Various parameters like pulsatility index (PI) and resistivity index (RI) of color Doppler are helpful in detection of preeclampsia and intrauterine growth restriction. The reference ranges of the various parameters like uterine artery PI and RI are mainly from western countries. The reference range for Indian Population is lacking. So the objective of the study is to construct reference range of uterine artery for women from eastern India.Material and MethodIn this study, total 201 pregnant patients were included. Color Doppler of normal pregnant women was done at 18 to 22 weeks and then followed up at 28 to 32 weeks gestation. The uterine artery PI and RI was measured during pregnancy. The obtained data were tabulated and 5th, 25th, 50th, 75th, 90th and 95th percentile was calculated. The reference range was constructed according to gestational age starting from 18 to 22 weeks and then from 28 to 34 weeks. Statistical analysis was performed using SPSS.ResultThe main parameter observed are pulsatility and resistivity index of left and right uterine arteries first at 18 to 22 weeks and then followed up at 28 to 34 weeks. Our data suggests that as the gestational age increases both pulsatility and resistivity index decreases. The cut off value for reference range was taken up to 95th percentile. Anything above 95th percentile is abnormal. The reference range for left uterine artery pulsatility index was found to be 1.19 to 1.16 at 18 to 22 weeks, 1.09 at 28 weeks while 0.89 at 34 weeks. Similarly, the reference range for resistivity index was found to be 0.61 at 18 to 22 weeks while it decreases to 0.54 at 28 to 34 weeks.ConclusionReference range of uterine artery doppler indices for the local population is very useful tool to early prediction of Preeclampsia and IUGRs of that population and can aid in timely treatment of mother and baby. Our data shows decrease in pulsatility and resistivity index with increase in the gestational age.

APPLYING VALUE UTERINE DOPPLER ASSOCIATED WITH PREECLAMPSIA

2016 ◽  
pp. 57-64
Author(s):  
Thi Linh Giang Truong ◽  
Vu Quoc Huy Nguyen ◽  
Quang Vinh Truong ◽  
Van Duc Vo
Keyword(s):  
Cohort Study ◽  
Key Words ◽  
Doppler Ultrasound ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Fetal Distress ◽  
Central Hospital ◽  
Study Results ◽  
Key Words Doppler

Background: Study on the correlation between the values of the Uterine Doppler with the type of preeclamsia and using uterine Doppler and predict fetal distress. Methods: Study on 116 patients with pre-eclampsia at Obs. & Gyn. Department - Hue Central Hospital were taken by an prospective cohort study. Results: There was correlation between morphology of uterine Doppler waves with the type of preeclamsia and fetal distress. Among 46 patients with server preeclamsia, the rate of abnormal of waves uterine Doppler is 78,2 %, and the rate of abnormal of waves uterine Doppler is 22% and fetal. This research also evaluate the relation between uterine Doppler with the fetal distress. The group patients with fetal distress also have the rate of abnormal uterine Doppler is 86,6% and the rate of nomal uterine dopple is 13,4 %. Conclusion: There was the correlation between the values of the Uterine Doppler with the type of preeclamsia and predict fetal distress. The value of uterine Doppler ultrasound can be predict the ricks happening for mother and fetal distress with preeclampsia. Key words: Doppler ultrosound, uterine Doppler, fetal distress, preeclampsia, IUGR.

Generalization of a genetic risk score for time to first albuminuria in children with sickle cell anaemia: SCCRIP cohort study results

2021 ◽  
Author(s):  
Sara R. Rashkin ◽  
Evadnie Rampersaud ◽  
Guolian Kang ◽  
Kenneth I. Ataga ◽  
Jane S. Hankins ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sickle Cell ◽  
Risk Score ◽  
Genetic Risk ◽  
Sickle Cell Anaemia ◽  
Genetic Risk Score ◽  
Study Results

scholarly journals Rationale, Design, and Methodology of a Prospective Cohort Study for Coping with Behavioral and Psychological Symptoms of Dementia: The RECage Project

2021 ◽  
Vol 80 (4) ◽  
pp. 1613-1627
Author(s):  
Eleni Poptsi ◽  
Magda Tsolaki ◽  
Sverre Bergh ◽  
Bruno Mario Cesana ◽  
Alfonso Ciccone ◽  
...  
Keyword(s):  
Cohort Study ◽  
Psychotropic Drug ◽  
Psychological Symptoms ◽  
Cost Of Care ◽  
Community Dwelling ◽  
Drug Consumption ◽  
Study Results ◽  
Short And Long Term ◽  
Behavioral And Psychological Symptoms

Background: Behavioral and psychological symptoms of dementia (BPSD) are quite challenging problems during the dementia course. Special Care Units for people with dementia (PwD) and BPSD (SCU-B) are residential medical structures, where BPSD patients are temporarily admitted, in case of unmanageable behavioral disturbances at home. Objective: RECage (REspectful Caring for AGitated Elderly) aspires to assess the short and long-term effectiveness of SCU-Bs toward alleviating BPSD and improving the quality of life (QoL) of PwD and their caregivers. Methods: RECage is a three-year, prospective study enrolling 500 PwD. Particularly, 250 community-dwelling PwDs presenting with severe BPSD will be recruited by five clinical centers across Europe, endowed with a SCU-B, for a short period of time; a second similar group of 250 PwD will be followed by six other no-SCU-B centers solely via outpatient visits. RECage’s endpoints include short and long-term SCU-B clinical efficacy, QoL of patients and caregivers, cost-effectiveness of the SCU-B, psychotropic drug consumption, caregivers’ attitude toward dementia, and time to nursing home placement. Results: PwD admitted in SCU-Bs are expected to have diminished rates of BPSD and better QoL and their caregivers are also expected to have better QoL and improved attitude towards dementia, compared to those followed in no-SCU-Bs. Also, the cost of care and the psychotropic drug consumption are expected to be lower. Finally, PwD followed in no-SCU-Bs are expected to have earlier admission to nursing homes. Conclusion: The cohort study results will refine the SCU-B model, issuing recommendations for implementation of SCU-Bs in the countries where they are scarce or non-existent.

Childhood phenotypic manifestations of genetic risk for anorexia nervosa in the Norwegian Mother, Father and Child Cohort Study (MoBa)

2021 ◽  
Author(s):  
Ziada Ayorech ◽  
Neil Martin Davies ◽  
Hunna Watson ◽  
Zeynep Yilmaz ◽  
Martin Tesli ◽  
...  
Keyword(s):  
Mental Health ◽  
Body Mass Index ◽  
Early Childhood ◽  
Anorexia Nervosa ◽  
Cohort Study ◽  
Genetic Risk ◽  
Aggressive Behaviour ◽  
Eating Problems ◽  
Future Studies ◽  
Study Results

Anorexia nervosa (AN) polygenic liability has been associated with mental health traits, eating problems, and body mass index (BMI) in adolescence and adulthood, but little is known about its manifestations in early childhood. We explore AN polygenic score (PGS) associations with six childhood domains: BMI, eating problems, neurodevelopment, emotional problems, disruptive/aggressive behaviour, and temperament/personality in 15,205 children from the Norwegian Mother, Father and Child Cohort Study. Results did not support associations between AN PGS and developmental phenotypes in girls. For boys, we observed an association between AN PGS and higher temperamental fussiness at 6 months, (b= 0.036 [95% CI=0.010,0.061]). Our results suggest that genetic risk for AN as indexed by the PGS has few observable manifestations in key neurodevelopmental domains in the first 8 years of life. Future studies with more powerful PGS that track children longer may aid in understanding how and when genetic risk for AN manifest developmentally.

scholarly journals Three-Dimensional Power Doppler Analysis of Cerebral Circulation in Normal and Growth-Restricted Fetuses

2009 ◽  
Vol 29 (9) ◽  
pp. 1609-1618 ◽  
Author(s):  
Jose L Bartha ◽  
Eva M Moya ◽  
Blas Hervías-Vivancos
Keyword(s):  
Doppler Ultrasound ◽  
Cerebral Circulation ◽  
Pulsatility Index ◽  
Power Doppler ◽  
Three Dimensional ◽  
Flow Index ◽  
Power Doppler Ultrasound ◽  
3D Power Doppler ◽  
Doppler Indices ◽  
Vascularization Index

The objective of the present study was to evaluate fetal cerebral circulation by using three-dimensional (3D) power Doppler ultrasound in normal and growth-restricted fetuses. A total of 100 normal grown fetuses were compared with other 25 with growth restriction (FGR). Three-dimensional power Doppler ultrasound was used to assess fetal cerebral 3D vascular indices: vascularization index, flow index (FI), and vascularization flow index (VFI). Both FI and VFI correlated positively with gestational age. On average, all the 3D vascular indices were increased in fetuses with FGR. The proportion of fetuses detected as having hemodynamic redistribution was higher when using 3D power Doppler indices than by means of the middle cerebral artery pulsatility index (52% versus 20%, P = 0.002). In conclusion, two of the three indices increased during gestation. All the fetal cerebral 3D vascular indices are increased in fetuses with FGR. In these fetuses, there were more cases suggesting hemodynamic redistribution than expected by conventional Doppler studies.

Effect of fetal heart rate on umbilical arterial Doppler indices.

1989 ◽  
Vol 8 (4) ◽  
pp. 215-218 ◽  
Author(s):  
P Yarlagadda ◽  
L Willoughby ◽  
D Maulik
Keyword(s):  
Heart Rate ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Doppler Indices

scholarly journals Exploring the Role of Microbiome in Susceptibility, Treatment Response and Outcome among Tuberculosis Patients from Pakistan; Study Protocol for a Prospective Cohort Study (Micro-STOP)

2021 ◽  
Author(s):  
Muhammad Shahzad ◽  
Zia UlHaq ◽  
Simon C Andrews
Keyword(s):  
Immune Response ◽  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Gut Microbiome ◽  
Prospective Cohort ◽  
Treatment Success ◽  
Anthropometric Measurement ◽  
Microbiome Diversity ◽  
Study Results

Introduction: Tuberculosis (TB) caused by Mycobacterium tuberculosis is a common infectious disease associated with significant morbidity and mortality, especially in low and middle-income countries. Successful treatment of the disease requires prolonged intake (6 to 8 months) of multiple antibiotics with potentially detrimental consequences on the composition and functional potential of the human microbiome. The protocol described in the current study aims to identify microbiome (oral and gut) signatures associated with TB pathogenesis, treatment response and, outcome in humans. Methods and analysis: Four hundred and fifty, newly diagnosed TB patients from three district levels (Peshawar, Mardan, Swat) TB diagnosis and treatment centers will be recruited in this non-interventional, prospective cohort study and will be followed and monitored until treatment completion. Demographic and dietary intake data, anthropometric measurement and blood, stool and salivary rinse samples will be collected at baseline, day 15, month-2 and end of the treatment. Additionally, we will recruit age and sex-matched healthy controls (n=30). Blood sampling will allow monitoring of the immune response during the treatment, while salivary rinse and fecal samples will allow monitoring of dynamic changes in oral and gut microbiome diversity. Within this prospective cohort study, a nested case-control study design will be conducted to assess perturbations in oral and gut microbiome diversity (microbial dysbiosis) and immune response and compare between the patients groups (treatment success vs failure). Ethics and dissemination The study has received ethics approval from the Ethic Board of Khyber Medical University Peshawar, and administrative approval from the Provincial TB Control Program of Khyber Pakhtunkhwa, Pakistan. The study results will be presented at national and international conferences and published in peer-reviewed journals. Trial registration number: NCT04985994; pre-results

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